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Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Newly Identified Cellular Mechanism Enhances Photosynthesis in Marine Phytoplankton

Take a deep breath. Now take nine more. According to new research, the amount of oxygen in one of those 10 breaths was made possible thanks to a newly identified cellular mechanism that promotes photosynthesis in marine phytoplankton.

1 Jun 2023

Researchers Develop Novel Metal-Protein Hybrid Complex With Enhanced ROS Activity

Cu(II) complexes with low molecular weight are functional superoxide-dismutase (SOD) models with superior reactive oxygen species (ROS) removal ability.

30 May 2023

Game-Changing Research Shows Astrocytes as Key Regulators of Alzheimer's Disease Progression

Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates-;a telltale sign of Alzheimer's brain pathology-;never go on to develop Alzheimer's-associated dementias?

30 May 2023

Salmonella Employs Unique Tactics to Escape Cellular Defense

Salmonella enterica, a disease-causing bacterium, employs a variety of strategies to evade the human body’s defense mechanisms, much like thieves.

29 May 2023

Study Provides a New Picture of How Bacterial Cells Repair Faulty DNA

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

17 May 2023

Increase in Certain Bacterial Species Indicates Intestinal Candida Fungi Overgrowth

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.

15 May 2023

Researchers Develop a System to Deliver Antioxidants to the Mitochondria

A new drug delivery system delivers an antioxidant directly to mitochondria in the liver, mitigating the effects of oxidative stress.

11 May 2023

Research Sheds Light on How Nature has Optimized Photosynthesis

Photosynthesis plays a crucial role in shaping and sustaining life on Earth, yet many aspects of the process remain a mystery.

4 May 2023

Biological Condensates Harbor Electrical Imbalances That Spark "Redox" Reactions

The human body relies heavily on electrical charges. Lightning-like pulses of energy fly through the brain and nerves and most biological processes depend on electrical ions traveling across the membranes of each cell in our body.

2 May 2023

UMass Amherst Researcher Receives New Innovator Grant

Lutz Grossmann is on a scientific quest to develop tasty, animal-free protein that has a minimal carbon footprint and is generated without the use of agricultural land, which is a common and more stressed source of the world’s food supply.

27 Apr 2023

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Researchers have discovered that if oxidative stress destroys protein factories known as ribosomes, repair crews may go in to assist in repairing the damage so that production may restart rapidly.

26 Apr 2023

Macrophages in the Duodenum Play an Important Role in Iron Deficiency

Approximately one to two milligrams of the trace element must be supplied daily through food and finally absorbed in the duodenum for a balanced iron metabolism.

21 Apr 2023

Using Cellular Reprogramming to Make the Heart Function Like New Again

A recent study using mice has revealed a way to turn back the clock after heart attack. The researchers behind the work used RNAs to instruct cells in an injured heart to eliminate scar tissue and recreate cardiac muscle, allowing the heart to function like new again.

20 Apr 2023

Microalgae Grown in the Lab for Producing Biofuel

A group of researchers at the State University of Campinas (UNICAMP) in Brazil have grown microalgae under controlled conditions in a laboratory in order to use their metabolites, especially lipids, with the prime purpose of producing biofuel.

20 Apr 2023

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

At St Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard, researchers have shown how prime editing could help correct the mutation that results in sickle cell disease in a possibly curative method.

18 Apr 2023

UCF Scientists Develop a Digital Topographical Map of the Cardiac Sympathetic Neural Network

A team of UCF College of Medicine researchers has created a digital topographical map of the cardiac sympathetic neural network, the region that controls the body's heart rate and its "fight-or-flight" response.

18 Apr 2023

Lab-Grown Fat Could Give a More Realistic Texture and Flavor to Cultured Meat Grown from Cells

Researchers at Tufts University have successfully bulk-produced fat tissue in the lab that has a similar texture and make-up to fat tissue naturally occurring in animals.

6 Apr 2023

DELLA Proteins: The Road to the Next Green Revolution

Despite being largely unchanged for over 450 million years, a family of “promiscuous” proteins that are present in all land plants is responsible for a wide range of plant activities.

5 Apr 2023

First atomic-level structure of 'oil-eating' enzyme paves way for bioengineered catalysts

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have produced the first atomic-level structure of an enzyme that selectively cuts carbon-hydrogen bonds-;the first and most challenging step in turning simple hydrocarbons into more useful chemicals.

31 Mar 2023