pH News and Research

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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

New technique to hunt down mutations that cause cancer drug resistance

Using a virus to purposely mutate genes that produce cancer-driving proteins could shed light on the resistance that inevitably develops to cancer drugs that target them, a new study led by UT Southwestern scientists suggests.

11 Aug 2021

Muscle protein tied to physical fitness in youth and age-associated diseases

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

9 Aug 2021

Study shows promising results for treating muscular dystrophies with umbilical cord-derived MSCs

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord.

28 Jul 2021

Already characterized active substances exhibit unexpected effects

Every innovative drug starts with the search for an active substance targeting key players in disease-related processes.

23 Jul 2021

DRI study receives $1.5M grant to investigate the formation of harmful compounds by e-cigarettes

Scientists with the Desert Research Institute Organic Analytical Laboratory in Reno, Nev., led by Andrey Khlystov, Ph.D., have been awarded a $1.5M grant from the National Institutes of Health (NIH) to study the formation of dangerous compounds by electronic cigarettes (e-cigarettes).

21 Jul 2021

Persister bacteria manipulate intracellular pH for surviving antibiotic treatment

Decreasing bacterial acidity could help reduce antimicrobial resistance by eliminating bacteria that can survive being treated with antibiotics.

From University of Exeter 21 Jul 2021

Gene therapy may be safe and effective in treating AADC deficiency

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

19 Jul 2021

Brainless slime mold uses its body to sense mechanical cues in the environment

If you didn't have a brain, could you still figure out where you were and navigate your surroundings? Thanks to new research on slime molds, the answer may be "yes."

15 Jul 2021

Study evaluates the conflicts between alternative energy strategies and biodiversity conservation

Climate change mitigation efforts have led to shifts from fossil-fuel dependence to large-scale renewable energy.

14 Jul 2021

New method yields 10 times more accessible details of gene activity in individual cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

7 Jul 2021

New approach uses engineered yeast cells to study proteins that regulate gene expression

Researchers have developed a more efficient platform for studying proteins that play a key role in regulating gene expression. The approach uses engineered yeast cells to produce enzyme and histone proteins, conduct biochemical assays internally, and then display the results.

2 Jul 2021

Determining class A drug use from a single fingerprint

AZoLifeSciences speaks to Dr. Catia Costa about her latest research that showed how class A drug use can be determined from a single fingerprint.

From University of Surrey 29 Jun 2021

Genetic treatment may provide a new approach to addressing obsessive-compulsive disorder (OCD)

For the first time, scientists have linked distinct patterns of genetic mutations with OCD in humans using genome-wide analysis.

29 Jun 2021

A new method to efficiently produce biofuels from discarded plant matter

More corn is grown in the United States than any other crop, but we only use a small part of the plant for food and fuel production; once people have harvested the kernels, the inedible leaves, stalks and cobs are left over.

From Massachusetts Institute of Technology (MIT) 28 Jun 2021

Researchers identify key cells involved in childhood brain cancer

A new study coordinated by the University of Trento could have identified the cell of origin of medulloblastoma—a malignant tumor in children that affects the central nervous system. In this study, scientists have used organoids to replicate the tumor tissue, for the first time.

25 Jun 2021

New airway model boosts COVID-19 research

A research team has successfully built a model of lung cells that can be used to simulate how COVID-19 infects the airways.

22 Jun 2021

Genetically engineering NK cells can target and kill glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

18 Jun 2021

Study shows how ocean warming and acidification could affect lifecycle of crustaceans

Albeit very small, with a carapace width of only 3 cm, the Atlantic mangrove fiddler crab Leptuca thayeri can be a great help to scientists seeking to understand more about the effects of global climate change.

15 Jun 2021

New “phase separation” protects against premature aging, neurological disorders

According to a new study, a mechanism through which an RNA, called NORAD, drives the Pumilio protein to create liquid droplets in cells—similar to oil in water—appears to closely control the activity of this protein.

11 Jun 2021

Study reveals new insights into role of polyphenols in the soil microbiome

Fruits, vegetables, red wine and chocolate are all rich in polyphenols, natural plant compounds that double as cancer-fighting antioxidants. We can access these foods' health benefits because the microbes in our guts happily feast on them, breaking them down into smaller chemical components.

10 Jun 2021