therapeutics News and Research

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mEnrich-seq: A High-Specificity Bacterial Enrichment Technique for Microbiome Research

In a landmark study recently published in the journal Nature Methods, researchers at the Icahn School of Medicine at Mount Sinai have unveiled mEnrich-seq-;an innovative method designed to substantially enhance the specificity and efficiency of research into microbiomes, the complex communities of microorganisms that inhabit the human body.

5 Jan 2024

Research Reveals Unforeseen Functions for Autophagy Genes in Neuronal Health and Aging

Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. In the January 4th issue of Nature Aging, it was noted that scientists from the Buck Institute, Sanford Burnham Prebys and Rutgers University have uncovered possible novel functions

5 Jan 2024

Improved Mapping of Small-Molecule Binding Sites in Cells

Researchers at Scripps Research created a novel, high-resolution method for identifying putative treatment targets on proteins in living cells.

3 Jan 2024

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.

26 Dec 2023

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

26 Dec 2023

Innovative Machine Learning Tool Predicts Functional Consequences of Genetic Variants

In a recent research, scientists from the Icahn School of Medicine at Mount Sinai unveiled LoGoFunc, an innovative computational tool designed to forecast both pathogenic gain- and loss-of-function variants throughout the genome.

15 Dec 2023

Scientists Crack the Code for Artificial DNA

The genetic code is composed of just four letters representing the four nucleotides, which are the fundamental building blocks of DNA.

14 Dec 2023

Molecular Blueprint for Understanding Brain Function

For the very first time, a global team of researchers has successfully crafted a comprehensive cell atlas for an entire mammalian brain.

14 Dec 2023

Free AI Drug Discovery Course Surpasses 2,500 Users

An online course on Disease Modeling and Target Discovery launched 7 months ago by clinical stage generative artificial intelligence (AI)-driven biotechnology company Insilico Medicine has surpassed 2,500 users.

12 Dec 2023

Researchers Redesign the Future of mRNA Therapeutics

Scientists have unearthed that errors in the interpretation of therapeutic mRNA by the cell’s decoding apparatus can incite an inadvertent immune reaction within the body.

7 Dec 2023

Evonetix Announces Agreement for Revolutionary Gene Synthesis Platform With Analog Devices

EVONETIX LTD (‘Evonetix’), the company developing semiconductor scale technology to improve access to gene synthesis, today announces the signing of a joint development agreement and commercial supply agreement with Analog Devices, Inc. (ADI), a global semiconductor leader.

6 Dec 2023

Camena Bioscience Appoints Dr. Nicola Thompson as Chair of the Board

Camena Bioscience, a synthetic biology company providing genes to the pharmaceutical and biotechnology industries, today announced it has appointed Dr Nicola Thompson as Chair of its Board of Directors.

From Camena Bioscience 6 Dec 2023

No Container, No Problem—Studying Self-Contained Spheres of Liquid Protein in Space Could Help Improve Medicine on Earth

How could studying liquid drops of protein solution in space help solve an Achilles’ heel in medicine production on Earth? Find out in the latest issue of Upward, the official magazine of the International Space Station (ISS) National Laboratory.

5 Dec 2023

Discovery Park Ventures Expands Fund to £3m to Invest in More Innovative Science and Technology Start-Ups

Discovery Park Ventures (DPV) announces the expansion of its early-stage life science fund from £1m to £3m, in order to capitalise on exciting investment opportunities and support its existing portfolio.

5 Dec 2023

Researchers Redesign Future mRNA Therapeutics to Prevent Potentially Harmful Immune Responses

Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body.

5 Dec 2023

New Method Allows Scientists to Observe Multiple Signals in Living Cells

Living cells are bombarded with many kinds of incoming molecular signal that influence their behavior.

29 Nov 2023

FLSHclust Unveils 188 Novel CRISPR-Associated Gene Modules

Employing a groundbreaking algorithm named FLSHclust (“flash clust”), scientists have unearthed 188 uncommon and previously undiscovered CRISPR-associated gene modules, among billions of protein sequences. This includes the identification of a novel type VII CRISPR-Cas system.

24 Nov 2023

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

therapeutics News and Research

mEnrich-seq: A High-Specificity Bacterial Enrichment Technique for Microbiome Research

Research Reveals Unforeseen Functions for Autophagy Genes in Neuronal Health and Aging

Improved Mapping of Small-Molecule Binding Sites in Cells

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Innovative Machine Learning Tool Predicts Functional Consequences of Genetic Variants

Scientists Crack the Code for Artificial DNA

Molecular Blueprint for Understanding Brain Function

Free AI Drug Discovery Course Surpasses 2,500 Users

Researchers Redesign the Future of mRNA Therapeutics

Evonetix Announces Agreement for Revolutionary Gene Synthesis Platform With Analog Devices

Camena Bioscience Appoints Dr. Nicola Thompson as Chair of the Board

No Container, No Problem—Studying Self-Contained Spheres of Liquid Protein in Space Could Help Improve Medicine on Earth

Discovery Park Ventures Expands Fund to £3m to Invest in More Innovative Science and Technology Start-Ups

Researchers Redesign Future mRNA Therapeutics to Prevent Potentially Harmful Immune Responses

New Method Allows Scientists to Observe Multiple Signals in Living Cells

FLSHclust Unveils 188 Novel CRISPR-Associated Gene Modules

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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