The Xevo G3 QTof empowers users to obtain maximum information about the analytes, from in-depth characterization to precise quantitation, ensuring complete confidence in the findings.
As the newest addition to the Xevo product line, this system expands the ease of use and range of characterization for both complex biotherapeutics and challenging small molecules. Enhanced ion optics design delivers consistent robustness and performance, integrating core technology for comprehensive quantitation. Supported by a growing suite of informatics tools, the Xevo G3 QTof provides a complete solution for laboratory needs.
The characterization of analytes just evolved – introducing the new generation of Xevo. Image Credit: Waters Corporation
Get a step change in chromatographic performance when the Xevo G3 QTof pairs with the ACQUITY Premier System. Image Credit: Waters Corporation
Overview
Ultimate Performance: Achieve comprehensive analyte coverage with enhanced transmission of low-mass, labile compounds, while maintaining exceptional performance in established biopharmaceutical workflows and meeting the evolving demands for characterizing novel therapeutic modalities.
Connected Productivity: Streamline the workflows across development, manufacturing, and monitoring/quality control (QC) by integrating the waters_connect ecosystem with the Xevo G3 QTof and the BioAccord System featuring ACQUITY Premier.
Extended Flexibility: A wider dynamic range both within and between spectra enhances the quantitative analysis, enabling comprehensive quantitative and qualitative analysis that is ideal for screening and targeted applications.
Unquestioned Confidence: Updated ion optics ensure consistent data quality and reproducibility, maintaining high performance and productivity over extended periods.
Recommended Use: Analyze and quantify various molecules using a single, powerful analytical instrument.
Ultimate Performance for a Range of Analytes
Xevo G3 QTof provides a significant increase in sensitivity for challenging labile compounds. Image Credit: Waters Corporation
Expect more versatility from the analytical systems to expand the lab's potential. The Xevo G3 QTof integrates innovative technologies that enhance the characterization of complex biologics (including a calibration range up to m/z 16,000 and specialized informatics) while also improving the analysis of challenging small molecules (with updated ion optics and a detection system designed to maximize transmission and dynamic range). Featuring the StepWave XS, the Xevo G3 QTof efficiently transmits low-mass, labile compounds, allowing you to achieve greater compound coverage and analytical accuracy.
Connected Productivity for Harmonized Workflows
waters_connect supports deployment of compliance-ready LC-MS workflows throughout development and into production and QC lab environments. Image Credit: Waters Corporation
Consistent workflows throughout development, manufacturing, and quality control are crucial to maximizing lab efficiency. The Xevo G3 QTof excels at characterizing biomolecules and processes, making it perfect for initial investigations before moving to specific attribute monitoring assays on either the Xevo G3 QTof or the BioAccord System with ACQUITY Premier.
The waters_connect ecosystem provides smooth, compliance-ready workflows for understanding and tracking biotherapeutic variations. By connecting systems and users through waters_connect, users gain security-controlled access, complete data traceability, and the operational efficiency and scalability of a networked deployment.
Delivering Qualitative and Quantitative Performance
Demonstrating 5 orders of linear dynamic range in Tof-MRM mode. Image Credit: Waters Corporation
Optimize the lab's productivity with the Xevo G3 QTof, a versatile, multi-functional instrument that provides high-quality quantitative and qualitative data. This evolved system is specifically designed to meet these demands, featuring core technology enhancements that deliver a linear dynamic range of up to five orders of magnitude for targeted analysis.
For untargeted and screening experiments, the Xevo G3 QTof excels at detecting and quantifying components of interest even in the most complex matrices, offering up to a fourfold increase in in-spectrum dynamic range.
Unquestioned Confidence with Consistent Robustness and Reproducibility
Minimize contamination and increase uptime with optimized ion optics. Image Credit: Waters Corporation
Instrument stability and uptime are essential in fast-paced, high-throughput labs. The refined design of the Xevo G3 QTof is engineered for consistent robustness and reproducibility, ensuring sustained performance and productivity over extended periods. Featuring an updated ion optics design and optimized ion beam conditioning, the Xevo G3 QTof is a dependable analytical workhorse that consistently delivers high-quality data.