Antibodies and Immunology News and Research

Latest Antibodies and Immunology News and Research

Microglia Replacement Therapy Offers Hope for Genetic Disorders Affecting the Brain

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

7 Aug 2025

Parkinson’s Gene Mutation Blocks Vital Neuroprotective Signals

GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a shared pathogenic pathway.

7 Aug 2025

CD276 Antibody Strategy Offers Hope For Immune-Resistant Lung Tumors

The study highlights 8H8_SDIE's role in activating NK cells against NSCLC, offering a new strategy for patients resistant to conventional immunotherapies.

6 Aug 2025

UCLA Researchers Reprogram Stem Cells to Produce Continuous Cancer-Fighting T Cells

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents.

5 Aug 2025

AI-Powered Protein Design Opens Doors to New T-Cell Based Immunotherapies

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.

4 Aug 2025

Bacterial Battle Strategies Involve Durable Amyloid Armor

Amyloids are perhaps best known as a key driver of Alzheimer's disease.

30 Jul 2025

PD-1 Guides T Cells to Become Long-Term Immune Defenders in the Skin

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.

30 Jul 2025

Proteins as a Natural Weapon Against Predatory Bacteria

Amyloids are perhaps best recognized as a major cause of Alzheimer’s disease.

30 Jul 2025

Blocking TG2 Could Help Immune Cells Attack Ovarian Tumors

The study reveals TG2's role in ovarian cancer metastasis, suggesting that its inhibition could re-educate the immune system for better anti-tumor efficacy.

30 Jul 2025

AI-Designed Proteins Offer New Hope for Personalized Cancer Immunotherapy

Precision cancer treatment on a larger scale is moving closer after researchers have developed an AI platform that can tailor protein components and arm the patient's immune cells to fight cancer.

29 Jul 2025

Multi-Omics Approaches Reveal New Insights into Colorectal Cancer Liver Metastasis

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

29 Jul 2025

Injectable Hydrogels Use Milk-Derived Vesicles to Promote Tissue Regeneration

Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.

29 Jul 2025

AI-Driven Precision for Next-Gen Cancer Immunotherapy

Consider how immune cells may be tailored to combat any type of cancer. T cell receptor (TCR) therapy has the potential to become the standard cancer treatment.

29 Jul 2025

New Computer Program Mimics Human and Animal Cell Behavior

Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body.

28 Jul 2025

Gene Editing Offers New Hope to Stop Malaria Transmission

Mosquitoes kill more people each year than any other animal. In 2023, the blood-sucking insects infected a reported 263 million people with malaria, leading to nearly 600,000 deaths, 80% of which were children.

24 Jul 2025

New Method Enables Precise Fatty Acid Delivery Without Albumin

Fatty acids (FAs) are essential to cell membrane formation, energy storage, and lipid metabolism. Yet, delivering them for research remains a challenge due to their insolubility in water and the reliance on albumin to facilitate transport.

23 Jul 2025

Improved Agrobacterium Strains Enhance Plant Genetic Engineering Efficiency

These mutations improve biocontainment, transformation stability, and overall performance in genetic engineering of plants.

22 Jul 2025

Immune Cells Use Central Actin Structures to Squeeze Through Tight Spaces

Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable three-dimensional tissues that make up our bodies.

22 Jul 2025

Researchers Combine AI and CRISPR to Rejuvenate Ovarian Function

Ovarian aging, characterized by diminishing egg reserves and quality, affects millions of women worldwide, often leading to infertility.

21 Jul 2025

mRNA Vaccine Supercharges Immunotherapy Against Cancer

An experimental mRNA vaccine improved the tumor-fighting benefits of immunotherapy in a mouse model study, bringing researchers one step closer to their aim of generating a universal vaccination to “wake up” the immune system against cancer.

21 Jul 2025