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New Approach Could Power the Development of Advanced Cell Therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

2 May 2023

How Bacteria Take Action to Break Out of Dormancy

Solving a riddle that has confounded biologists since bacterial spores -; inert, sleeping bacteria -; were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.

2 May 2023

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Recent research from Temple University’s Lewis Katz School of Medicine and the University of Nebraska Medical Center demonstrates that gene-editing therapy aimed at two targets - HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that aids the virus getting into cells—can effectively eliminate HIV infection.

2 May 2023

Novel 3D Structure can Serve as Blueprint to Engineer New BoNT/E Variants

A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).

28 Apr 2023

Receptor News and Research

New Approach Could Power the Development of Advanced Cell Therapies

How Bacteria Take Action to Break Out of Dormancy

The Pivotal Role of Combinatorial CRISPR Gene Editing in the Elimination of HIV-1 Infection

Novel 3D Structure can Serve as Blueprint to Engineer New BoNT/E Variants

High-Throughput Assay to Analyze the Effects of CAR-T Cells Using Image Cytometry

Some Promising Human Antibodies can Fight New Variants of SARS-CoV-2

Neuronal Activity Necessary and Sufficient to Drive Astrocyte Development

New, Improved Dual Version of Living Yeast Biosensor to Detect All Peptide Variants

Abnormal Immune Activity in Astrocytes Causes Dementia-Related Cognitive Deficits

UH Researcher Designs New Model Expressing the Most Common Disease Mutation in USH2A

A Protein Domain Could Lead to New Treatments for COVID-19

Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

Promoting Gut Health in Mice with Broccoli Consumption

UDCA Use Associated with Reduced Odds of COVID-19

Potential Treatment Pathway for IBD Emerges from Microbe-Gut Signaling Study

SARS-CoV-2 Spike Protein Induces Memory Loss After COVID-19

Study Represents a Paradigm Shift in Renal Physiology/Mammalian Salt Handling

Tighter Core of SARS-CoV-2 Spike Protein in New Variants Likely Improved the Virus's Ability to Infect Host Cells

Harnessing a natural bacterial system to deliver proteins in mice and human cells

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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