Immunotherapy News and Research

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Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

Study: Biomarker can predict response to immunotherapies in breast cancer patients

A biomarker that has proven to be a predictor for response to immunotherapies in melanoma patients also has clinical relevance for breast cancer patients, according to a new study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

28 Jul 2021

New advancement could improve immune system’s ability to search, destroy tumor

A new study has found a promising treatment that could enhance the ability of the human immune system to seek and destroy cancer cells inside the body.

28 Jul 2021

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

20 Jul 2021

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

20 Jul 2021

Scientists are paving the way for cancer treatments with fewer side effects

In recent years, immunotherapy has revolutionized the field of cancer treatment. However, inflammatory reactions in healthy tissues frequently trigger side effects that can be serious and lead to the permanent discontinuation of treatment.

5 Jul 2021

New method can improve the efficacy of promising treatment for recurrent glioblastoma

A promising treatment for melanoma and other types of cancers is neoadjuvant immune checkpoint blockade (ICB).

1 Jul 2021

Researchers show how Covid-19 causes long-lasting changes in the blood cells

Using real-time deformability cytometry, researchers at the Max-Planck-Zentrum für Physik und Medizin in Erlangen were able to show for the first time: Covid-19 significantly changes the size and stiffness of red and white blood cells - sometimes over months.

30 Jun 2021

Mayo Clinic researchers examine potential new CAR-T cell treatment for multiple myeloma

Researchers at Mayo Clinic Cancer Center are studying a potential new chimeric antigen receptor-T cell therapy (CAR-T cell therapy) treatment for multiple myeloma.

28 Jun 2021

Genetically engineering NK cells can target and kill glioblastoma stem cells

Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.

18 Jun 2021

Natural killer cells target breast cancer using the body’s immune system

In a recent study, researchers investigated how natural killer cells target breast cancer using the body's own immune system.

18 Jun 2021

Commonly used antidepressant drugs can also help the immune system to attack cancer

A class of drug called monoamine oxidase inhibitors is commonly prescribed to treat depression; the medications work by boosting levels of serotonin, the brain's "happiness hormone."

10 Jun 2021

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

Computer scientist Lydia Kavraki of Rice University's Brown School of Engineering has won a prestigious National Institutes of Health U01 grant to develop a new approach to model and analyze protein-ligand interactions in cancer research.

8 Jun 2021

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Treatment with an immunotherapy drug following kidney cancer surgery, prolonged disease-free survival rates in patients at high risk for recurrence, according to an interim report of a phase 3 clinical trial of adjuvant immunotherapy in this patient population.

4 Jun 2021

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Patients with high-risk melanoma who had a course of pembrolizumab after their surgery had a longer time before their disease recurred than patients who got either ipilimumab or high-dose interferon after surgery. These findings of a large SWOG Cancer Research Network clinical trial, S1404, will be presented at the ASCO annual meeting June 6, 2021.

4 Jun 2021

Newly identified protein helps tumors evade the immune system

Researchers at the Francis Crick Institute have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to a poorer chance of survival. The protein could become a target for future cancer treatments.

3 Jun 2021

NCI grants over $4.2 million to launch the Cancer Epitope Database and Analysis Resource

Researchers are about to welcome a new one-stop shop for crucial information on how the immune system targets cancers.

3 Jun 2021

Researchers discover what fuels the immune system’s “natural killers”

Natural killer (NK) cells, while having a name straight out of a Tarantino film, are allies of humans when it comes to combating cancer and infections.

3 Jun 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

Studies highlight different aspects of link between obesity and cancer

Multi-factorial metabolic and inflammatory abnormalities in obesity, independently or in combination, seems to be the critical biological link of obesity, cancer and racial/gender health disparities. However, the specific cross-talk between these factors remain elusive.

24 May 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021

Immunotherapy News and Research

Study: Biomarker can predict response to immunotherapies in breast cancer patients

New advancement could improve immune system’s ability to search, destroy tumor

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Scientists are paving the way for cancer treatments with fewer side effects

New method can improve the efficacy of promising treatment for recurrent glioblastoma

Researchers show how Covid-19 causes long-lasting changes in the blood cells

Mayo Clinic researchers examine potential new CAR-T cell treatment for multiple myeloma

Genetically engineering NK cells can target and kill glioblastoma stem cells

Natural killer cells target breast cancer using the body’s immune system

Commonly used antidepressant drugs can also help the immune system to attack cancer

NIH grant awarded to model and analyze protein-ligand interactions in cancer research

Immunotherapy following kidney cancer surgery prolonged disease-free survival rates

Immune therapy after surgery reduces recurrence risk in patients with high-risk melanoma

Newly identified protein helps tumors evade the immune system

NCI grants over $4.2 million to launch the Cancer Epitope Database and Analysis Resource

Researchers discover what fuels the immune system’s “natural killers”

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Studies highlight different aspects of link between obesity and cancer

Increased expression of DUSP16 molecule leads to cancer chemoresistance

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