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Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

UMSOM study suggests a genetic basis behind instantaneous human compatibility

Have you ever met someone you instantly liked, or at other times, someone who you knew immediately that you did not want to be friends with, although you did not know why?

2 Sep 2021

New drug delivery strategy could make it easier for patients to take their medications

In recent years, scientists have developed monoclonal antibodies -; proteins that mimic the body's own immune defenses -; that can combat a variety of diseases, including some cancers and autoimmune disorders such as Crohn's disease.

31 Aug 2021

Massive study identifies 579 genomic locations linked to self-regulating behaviors

Researchers have identified 579 locations in the human genome associated with a predisposition to self-regulation-related behaviors, including addiction and child behavioral problems. With data from 1.5 million people of European descent, the effort is considered to be one of the largest genome-wide association studies to date.

27 Aug 2021

Study reveals how two separate DNA changes may predict aggressive childhood leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination.

From The University of Utah 20 Aug 2021

New CRISPR-based technique for rapid screening of hundreds of genes in a single experiment

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

From The University of Utah 20 Aug 2021

Graphene covered with bactericidal molecules inhibits harmful biofilm formation

Bacterial infections associated with medical implants place a major burden on healthcare and cause great suffering to patients across the world.

11 Aug 2021

Study analyzes individuals’ stance on secondary genomic findings

Recent research disclosed that around half of the people who refused to receive secondary genomic findings switched opinions after their healthcare provider presented them with further information.

From National Human Genome Research Institute (NHGRI) 2 Aug 2021

Study analyzes the role of heart cell protein as a potential therapeutic for heart failure

Recent research identified that a protein involved in regulating calcium signaling within heart cells can play a vital role in the prevention of chronic heart failure.

From The University of Utah 29 Jul 2021

ACMG and Elsevier announce new partnership to publish 'Genetics in Medicine'

The American College of Medical Genetics and Genomics, the only nationally recognized US medical professional organization solely dedicated to improving health through the practice of medical genetics and genomics, and Elsevier, a global leader in research publishing and information analytics, are delighted to announce a new partnership to publish ACMG's official journal, Genetics in Medicine.

27 Jul 2021

Persister bacteria manipulate intracellular pH for surviving antibiotic treatment

Decreasing bacterial acidity could help reduce antimicrobial resistance by eliminating bacteria that can survive being treated with antibiotics.

From University of Exeter 21 Jul 2021

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

20 Jul 2021

Updated Families SHARE workbook helps people use family history to assess disease risk

The Families SHARE workbook was developed by researchers at the NHGRI, which is part of the National Institutes of Health (NIH).

12 Jul 2021

New research focuses on possible treatment options for childhood brain cancer

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.

11 Jun 2021

Scientists discover two drugs that provide effective SARS-CoV-2 suppression

COVID-19 continues to claim lives across the world and is infecting millions more. Although several vaccines have recently become available, making significant strides towards preventing COVID-19, what about the treatment of those who already have the infection?

From Tokyo University of Science 4 Jun 2021

Roots for obesity start in the first year of life, shows study

Researchers at Columbia University Mailman School of Public Health and Universidade Federal de Ciências da Saúde de Porto Alegre, Brazil found that when health workers were trained to promote infant healthy feeding practices to pregnant women their children consumed less fats and carbohydrates at 3 years of age and had lower measures of body fat at the age of 6.

2 Jun 2021

Scientists develop new method that enables single-cell RNA sequencing in large number of cells

RNA sequencing is a powerful technology for studying cells and diseases. In particular, single-cell RNA sequencing helps uncover the heterogeneity and diversity of our body.

2 Jun 2021

Successful class of therapeutics attack and shut down unique and harmful genes

A potential class of therapeutics that uses synthetic nucleic acids to attack and shut down harmful genes while preventing viral spread is gathering momentum.

18 May 2021

Combination of Omega-3S in supplements may blunt the cardiovascular benefits of EPA

Doctors often recommend Omega-3s to help patients lower their cholesterol and improve heart health. Those Omega-3s can come from fatty fish like salmon and mackerel, or supplements that often contain a combination of the acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

17 May 2021

New CAD technology may open up new frontiers in genome research

A new Computer Aided Design (CAD) platform for whole genome design is being launched by two pioneers in the world of biotech: Genome Project-write (GP-write) and Twist Bioscience.

13 May 2021