Infectious Diseases News and Research

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New cellular pathway can protect cells from infection by Ebola virus, coronavirus

Discoveries from the Benaroya Research Institute at Virginia Mason (BRI) have identified a new cellular protection pathway that targets a common vulnerability in several different pandemic viruses, and collaborators at Case Western Reserve University, Boston University School of Medicine and MRIGlobal have shown that this pathway can protect cells from infection by Ebola virus and coronaviruses, like SARS-CoV-2.

28 Aug 2020

First lethal mouse model established for COVID-19 infection

Army scientists have developed the first lethal mouse model of SARS-CoV-2, the virus that causes COVID-19, using mice that were genetically engineered to express the human ACE2 gene--a key mechanism by which the virus enters human cells.

28 Aug 2020

Study shows how individualization with pharmacogenomics could impact COVID-19 treatments

Over the past few months, a number of drugs have been under investigation to treat COVID-19 without well-established safety or data to support these claims.

28 Aug 2020

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

Each person's gut has a unique viral 'fingerprint'

Each person's gut virus composition is as unique as a fingerprint, according to the first study to assemble a comprehensive database of viral populations in the human digestive system.

25 Aug 2020

Lasting nature of IBD linked to long-lived immune cell that causes persistent inflammation

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide.

25 Aug 2020

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Given the global urgency of the COVID-19 pandemic, Microsoft's AI for Health program has stepped in to support the development and potential deployment of Vaxine's COVAX-19™ vaccine with a philanthropic grant.

25 Aug 2020

Study: Wastewater containing coronaviruses may be a serious threat

Wastewater containing coronaviruses may be a serious threat, according to a new, global study led by researchers from the Zuckerberg Institute for Water Research at Ben-Gurion University of the Negev (BGU).

25 Aug 2020

Researchers develop multiplex genetic diagnostic device for early detection, prevention of crop diseases

A research group composed of Professor Takayuki Shibata and his colleagues at the Department of Mechanical Engineering, Toyohashi University of Technology has applied a microfluidic chip technology to develop a multiplex genetic diagnostic device for the early detection and prevention of crop diseases.

24 Aug 2020

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that that high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2, the virus that causes COVID-19.

20 Aug 2020

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020

Influenza viruses can spread through the air on dust, fibers

Influenza viruses can spread through the air on dust, fibers and other microscopic particles, according to new research from the University of California, Davis and the Icahn School of Medicine at Mt. Sinai.

From The University of California, Davis 19 Aug 2020

Novel receptor protein can be a promising treatment for COVID-19

A novel receptor protein that binds to the SARS-CoV-2 virus and prevents it from entering cells may hold promise for treating COVID-19 and other coronavirus-related diseases, according to research published online Aug. 4 in the journal SCIENCE.

18 Aug 2020

NIH-supported research delineates how genetic variations cause atopic dermatitis

New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema.

17 Aug 2020

Study reveals why immunity boost from seasonal flu vaccines is not long lasting

A study from Emory Vaccine Center provides insights into why the boost in immunity from seasonal flu vaccination lasts for months but not years, unlike some childhood vaccinations.

14 Aug 2020

Study shows MARCH8 protein protects against infection through antiviral mechanisms

A protein known as MARCH8 protects humans from infection by tagging the vesicular stomatitis virus for destruction, while simply holding the HIV hostage.

12 Aug 2020

COVID-19 Prevention Network announces two trials to evaluate monoclonal antibodies

The COVID-19 Prevention Network (CoVPN) today announced two Phase 3 trials to determine whether monoclonal antibodies (mAbs) can prevent SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2020

Adapting the equipment and expertise of agtech labs could help combat pandemics

Just as redeploying a fleet of small British fishing boats helped during the Battle of Dunkirk, marshalling the research equipment and expertise of the many agtech labs around the world could help combat pandemics, say the authors of a just-published article in Nature Biotechnology.

11 Aug 2020

Test pinpoints which people with gonorrhea can be treated with ciprofloxacin

A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it.

10 Aug 2020

Study may point to new therapeutic options for COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

7 Aug 2020

Infectious Diseases News and Research

New cellular pathway can protect cells from infection by Ebola virus, coronavirus

First lethal mouse model established for COVID-19 infection

Study shows how individualization with pharmacogenomics could impact COVID-19 treatments

Scientists identify antigen valencies that work best in vaccine designs for HIV, SARS-CoV-2

Each person's gut has a unique viral 'fingerprint'

Lasting nature of IBD linked to long-lived immune cell that causes persistent inflammation

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Study: Wastewater containing coronaviruses may be a serious threat

Researchers develop multiplex genetic diagnostic device for early detection, prevention of crop diseases

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Influenza viruses can spread through the air on dust, fibers

Novel receptor protein can be a promising treatment for COVID-19

NIH-supported research delineates how genetic variations cause atopic dermatitis

Study reveals why immunity boost from seasonal flu vaccines is not long lasting

Study shows MARCH8 protein protects against infection through antiviral mechanisms

COVID-19 Prevention Network announces two trials to evaluate monoclonal antibodies

Adapting the equipment and expertise of agtech labs could help combat pandemics

Test pinpoints which people with gonorrhea can be treated with ciprofloxacin

Study may point to new therapeutic options for COVID-19

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