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Meta-Analysis Identifies Genome-Level Associations of FOXP4 Gene With Long COVID

New genome-wide meta-analysis shows FOXP4 gene variants elevate the risk of long COVID (PASC), linking genetic predisposition to persistent symptoms and lung dysfunction. Findings support tailored treatment approaches.

30 May 2025

Gut Microbiome Offers Clues to Detecting and Treating Gastrointestinal Diseases

Scientists have discovered a range of 'biomarkers' that could help to improve detection and treatment of gastrointestinal diseases (GIDs) such as gastric cancer (GC), colorectal cancer (CRC), and inflammatory bowel disease (IBD).

29 May 2025

New Research Reveals Yeast-Based Production of Human DNase1 Protein

Research on yeast-based production of human DNase1 offers a cost-effective alternative to mammalian cells, enhancing treatment options for cystic fibrosis.

29 May 2025

Protein Mapping Uncovers 'Molecular Fingerprint' for Insulin Sensitivity

Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

28 May 2025

Study Reveals How APOE Isoforms Impact Brain Microglia

A study reveals how APOE isoforms influence microglial activity in Alzheimer's, highlighting the need for targeted interventions based on genetic risk factors.

28 May 2025

Mutation Profiling Reveals Therapeutic Targets in Lung Squamous Cell Carcinoma

Lung Squamous cell carcinoma (LSCC) represents the second most common non-small cell lung cancer. Although studies identified adenocarcinoma-like driver mutations in LSCC using next-generation sequencing (NGS), the disease is challenging to treat due to the limited number of detectable mutations for targeted drug therapy.

27 May 2025

Study Shows How Age-Related Metabolic Decline Impairs the Efficacy of CAR-T Cell Therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

26 May 2025

Broad Spectrum Pathogen Detection Achieved Through Metagenomic Sequencing

A recent study on the application of Metagenomic next-generation sequencing (mNGS) found that mNGS can achieve early detection of pathogens and accelerate the development of targeted anti-infection treatment plans, thereby improving treatment outcomes and patient prognosis.

24 May 2025

New Stem Cell Islet Model Mimics Pancreatic Function More Accurately

Researchers led by Maike Sander, Scientific Director of the Max Delbrück Center, have developed a vascularized organoid model of hormone secreting cells in the pancreas.

24 May 2025

Machine Learning Reveals Molecular Profile Differences in Colorectal Cancer Patients

Scientists aiming to advance cancer diagnostics have developed a machine learning tool that is able to identify metabolism-related molecular profile differences between patients with colorectal cancer and healthy people.

24 May 2025

Scientists Engineer Proteins That Morph Like Nature’s Own

The ability to engineer shapeshifting proteins opens new avenues for medicine, agriculture, and beyond.

24 May 2025

New Genomic Score Predicts Risk of Progression in Multiple Myeloma

A new risk assessment score developed by researchers at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard reveals how multiple myeloma, a form of blood cancer, begins and progresses from precancerous to malignant states by tracing DNA mutations.

24 May 2025

New Bacterial Consortium can Inhibit Bacterial Pathogens in Aquaculture

A new study by Danish researchers has demonstrated that it is possible to develop a consortium of bacteria that can inhibit bacterial pathogens in aquaculture.

22 May 2025

Study Reveals Epigenetic Clues Behind Autism Development

Autism spectrum disorder (ASD) is a condition affecting the brain's development and often affects the ability of a person to perceive sensory information and social cues and socialize with others.

22 May 2025

Ultra-Rapid Genetic Test Revolutionizes Brain Tumor Diagnosis

Scientists and medics have developed an ultra-rapid method of genetically diagnosing brain tumors that will cut the time it takes to classify them from 6-8 weeks, to as little as two hours – which could improve care for thousands of patients each year in the UK.

21 May 2025