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Scientists Build a Genetic Map to Predict Bacterial Resistance Mechanisms

The bacteria Acinetobacter baumannii (A. baumannii) is a haunting presence in many hospitals in the United States, where more than one in 100 patients are treated for A. baumannii infections.

10 Nov 2025

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

Researchers Find "Hidden" Mutations by Tracing Protein Isoforms

Approximately 25 million individuals in the United States are affected by a rare genetic disorder, and a significant number of them face challenges not only due to the absence of effective treatments but also because of insufficient information regarding their condition.

10 Nov 2025

TRV-Mediated Gene Editing System Transforms Tomato Functional Genomics

CRISPR-Cas9 has revolutionized plant genome editing, yet its application in tomato remains limited due to the plant's recalcitrance to transformation and regeneration.

7 Nov 2025

Decoding DNA’s Spatial Organization With Precision Tools

DNA is more than simply a lengthy string of genetic code; it is a complex three-dimensional structure folded inside each cell. That means that the equipment used to examine DNA must be as sophisticated, capable of reading not just the code itself but also its spatial arrangement.

7 Nov 2025

Two Genetic Mapping Approaches Reveal Distinct Sides of Disease Biology

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows.

6 Nov 2025

Breakthrough Genomic Technique Expands View of Ocean Microbial Life

A new method vastly improves on the existing approach for single-cell genetic sequencing, enabling scientists to read the genomes of individual cells and viral particles in the environment more quickly, efficiently, and cost-effectively.

6 Nov 2025

Iowa State Researchers Highlight the Power of Genomic Selection in Modern Agriculture

Developing high-yielding, nutritious and climate-resilient crops is vital to safeguard the future of global food production.

5 Nov 2025

RNA Molecules Alter Genome Structure to Silence Critical Neuronal Genes During Stress

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

5 Nov 2025

New Genomic Method Unlocks Diagnoses for Rare Conditions

A new genomic method has enabled multiple people with rare conditions to receive diagnoses that were previously unattainable by identifying complex structural genetic changes that are often missed by standard tests.

4 Nov 2025

Cross-Ancestry Genomic Study Identifies Thirteen Genes Linked to Obesity

Obesity is a global epidemic affecting millions of people every day and is associated with comorbidities ranging from heart disease and Type 2 diabetes to osteoarthritis and social stigma.

31 Oct 2025

Genetic Variants Reveal Unexpected Link Between Obesity Risk and Cholesterol Levels

Individuals with a genetic profile that puts them at risk of obesity may not necessarily be at risk of having high cholesterol, UTHealth Houston researchers discovered.

31 Oct 2025

Discovery of a 3D Genomic Loop Boosts Yield and Sustainability in Rice Cultivation

A team of Chinese scientists has uncovered a hidden 3D structure in rice DNA that allows the crop to grow more grain while using less nitrogen fertilizer.

31 Oct 2025

Precision Genome Editing of D3 Gene Enhances Rice Architecture and Stress Resilience

By precisely editing the D3 gene, which regulates both plant height and tillering, researchers developed compact, high-tillering rice plants that maintain grain yield while showing enhanced resistance to bacterial blight.

30 Oct 2025

Researchers Discover Novel Clubroot Resistance Gene Crr5 in Chinese Cabbage

Clubroot disease, caused by Plasmodiophora brassicae, is a devastating soil-borne pathogen that severely threatens global production of cruciferous crops.

28 Oct 2025

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Drought stress disrupts plant growth, metabolism, and reproduction, with devastating effects on crop productivity worldwide.

27 Oct 2025

Study Reveals How TR4 Fungus Silences Banana Defense Genes

Bananas rank among the world's most valuable staple crops, yet their production faces severe losses from Fusarium wilt caused by Fusarium oxysporum f. sp. cubense (Foc) tropical race 4 (TR4).

24 Oct 2025

RNA-Based Molecular Switch Enhances Disease Resistance in Pears

In recent years, scientists have uncovered the remarkable regulatory power of long non-coding RNAs (lncRNAs) - RNA molecules once dismissed as "genetic dark matter."

24 Oct 2025

Disrupted Circadian Rhythms Alter Gene Activity in Alzheimer’s Disease

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

24 Oct 2025

Hidden RNA Inside a Gene Solves Decades-Old Telomere Mystery in Roundworms

An international research team led by Hiroki Shibuya at RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has solved a genetic mystery and revealed a previously unknown way that DNA can control what cells do.

24 Oct 2025