Liver News and Research

RSS

New Genetic Discovery Explains Why Colorectal Cancer Spreads so Quickly

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

23 Jun 2026

Decoding Hidden Metabolic Tissue Crosstalk via Advanced Proteomic Tracking

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

23 Jun 2026

New Progenitor Cell Platform Offers Scalable Source for Immunotherapy

In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of the progenitor cells that give rise to macrophages.

22 Jun 2026

Molecular Cell Study Explains Gut Microbiome Impact on Liver Genes

A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function like molecular "switches".

16 Jun 2026

Evolutionary Biology Unlocks Secret Toxins Hidden Inside Poison Dart Frogs

There is a group of colorful amphibians that are known for storing defensive alkaloids in glands on their skin.

16 Jun 2026

Single-Cell Spatial Mapping Resolves Complex Tissue Senotypes During Aging

A massive scientific initiative to decode how aging reshapes the human body reached a major milestone this month.

15 Jun 2026

New Internal Cellular Process Creates Cysteine When Primary Systems Fail

A molecular geneticist at Montana State University has discovered a cellular process once believed impossible by scientists – the creation of the amino acid cysteine within a living cell when the cell's primary systems to do so fail.

13 Jun 2026

Body Clock Protein Drives Macrophages Into Pro-Inflammatory States

Daily life is shaped by the solar day, influencing when we wake up, eat, work, and sleep. Inside the body, a similar internal timing system -present in nearly every cell- known as the circadian clock, synchronizes many biological functions such as sleep, metabolism, hormone release, and even the immune system's activity.

12 Jun 2026

Collagen Exists as Liquid-Like Droplets Inside Cells

According to a recent study from the Centre for Genomic Regulation (CRG) in Barcelona, collagen, the protein that forms skin, bones, tendons, and organs, occurs inside cells as a liquid-like droplet rather than the long, rigid rod portrayed in textbooks during the past fifty years.

12 Jun 2026

New Insights Into How Pancreatic Beta Cells Manage Protein Folding

Origami masters turn simple sheets of paper into ornate sculptures. In the origami of life, our cells must fold proteins into specific three-dimensional shapes before they can carry out their biological jobs.

12 Jun 2026

Building More Realistic Human Tissue Models With Assembloids

Assembloids combine organoids and specialized cells, creating advanced models for drug testing and regenerative medicine with improved physiological relevance.

11 Jun 2026

New Cell Therapy Modifies Natural Killer Cells Against Cancer

Scientists have made great progress in harnessing the body's own immune cells to treat so-called liquid tumors, cancers of the blood and lymphatic system.

11 Jun 2026

Webinar - Modality Agnostic Drug Discovery Strategies for Data Sparse Targets: Lessons Learned From Avammune & Cresset, Hosted by Visioneers

Are you working on data-sparse or novel targets? Join us June 11th to learn how Avammune progressed from early concepts to trial-stage candidates in this space.

From Cresset 4 Jun 2026

Study Shows How AI and Single Cell Science are Changing Modern Medicine

Recent technological advances have pushed the boundaries of cellular biology far beyond what was conceivable even decades ago

4 Jun 2026

Bispecific Antibodies Target Tumors While Sparing Healthy Tissue

A new generation of bispecific antibodies effectively targets cancer cells, minimizing toxicity and enhancing treatment precision in preclinical studies.

3 Jun 2026

Nanoparticles Boost Delivery of Lung Cancer Drugs 30-Fold

Lung cancer remains one of the world’s deadliest cancers, yet despite decades of effort to develop new drugs, many fail because they don’t stay in the body long enough to be effective or because they damage healthy organs.

1 Jun 2026

Ovarian Cancer Fluid Helps Tumors Evade Cell Death

Ascites in ovarian cancer rewires tumor metabolism, protecting cells from ferroptosis and promoting metastasis, revealing potential therapeutic targets.

27 May 2026

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

Genetic Engineering Creates an Immune System Cloak to Extend Bacterial Drug Circulation

While previous research from Johns Hopkins University is successfully completing clinical trials, University of Rhode Island College of Pharmacy Assistant Professor Kaitlin Dailey is expanding on that work to more specifically target tumors that are difficult or impossible to access, especially those associated with pancreatic cancer-one of the deadliest types.

21 May 2026