OCT News and Research

RSS

Researchers Capture Real-Time Molecular Movie of Penicillin Enzymatic Ring Closure

Researchers from the University of Oxford and international collaborators have revealed previously unseen rapid chemical stages in the formation of β-lactam antibiotics like penicillin, offering insights that can support future antibiotic development.

10 Oct 2026

Study Creates Global Single-Cell Map of Human Immune System Aging

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health.

10 Oct 2026

Microbe Retains Self-Replication Machinery While Discarding Almost All Metabolic Pathways

Scientists have discovered a previously unknown microorganism, which has the smallest genome ever found, that is possibly able to replicate and express its own genetic information.

10 Oct 2026

Granular Genetic Risk Prediction Enables Early Detection of Hearing Loss

The team, composed of investigators from clinical audiology, ear surgery and general otolaryngology, was led by co-first author Andie DeFreese, AuD, a clinical audiologist and PhD candidate in the Department of Hearing and Speech Sciences at Vanderbilt Health.

9 Oct 2026

Transposable Element Methylation Instability Impairs Overall Genomic Regulation in Large Breeds

Why do large dogs tend to live shorter lives than their smaller counterparts? According to a new study of nearly 900 dogs, the answer may be written into their epigenome. The findings reveal that larger and male dogs undergo accelerated molecular aging, with pronounced DNA methylation (DNAm) on the X chromosome and at transposable elements (TEs).

9 Oct 2026

Retrotransposon Reactivation Suggests Reverse Transcriptase Inhibitors Lower Cancer Risk

A tumor suppressor gene known as p53 is mutated in more than half of all cancers, but how it acts to prevent cancer formation is largely unknown.

9 Oct 2026

Ten Shared Gene Clusters Map Common Immune Response Pathways Across Diseases

Researchers have identified patterns of gene activity associated with severe COVID-19 in children that are shared with other serious respiratory infections.

9 Oct 2026

Studies Redefine Lactation Biology Through Computational Multi-Omics and Mammary Metabolic Modeling

A study led by researchers at NYU Grossman School of Medicine identified shared molecular patterns in human milk that link maternal nutrition, mammary gland biology, and infant growth.

9 Oct 2026

Prime Editing Generates Genomic Ticker Tapes Tracing Millions of Developing Cells

Growing inside each of us is a cellular family tree.

9 Oct 2026

Genetic Analysis of Spotted Bats Traces Evolution Across Time

Understanding changes in North American bat populations is critical to measuring risk of extinction from emerging threats such as habitat loss, climate change, white nose syndrome and other disturbances.

8 Oct 2026

Ancient Gut Microbes Traveled Globally With Prehistoric Human Ancestors

As waves of humans left Africa tens of thousands of years ago, eventually populating the entire planet, they were joined on their world-conquering ride by the trillions of microorganisms that compose the gut microbiome.

8 Oct 2026

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease.

8 Oct 2026

Aldabra Giant Tortoise Genome Provides Evolutionary Blueprint for Cellular Resilience

Researchers studying a giant tortoise named Jonathan say it's not just good genes, but lack of genetic wear and tear that have kept him going for nearly two centuries.

8 Oct 2026

Mitochondrial Genome Dynamics Influence Intrinsic Tumor Aggressiveness

Mitochondria are small organelles within cells that play a central role in vital cellular processes, especially energy production.

8 Oct 2026

Ancient DNA Reveals Extinct Bovine Species in Southern Siberia

DNA analyses of ancient remains have revealed a previously unknown extinct bovine species that inhabited southern Siberia during and even before the last Ice Age.

6 Oct 2026

Undigested Cellular Waste Secretes Toxic Signals That Zombify Surrounding Tissue

As we grow older, our bodies accumulate "zombie cells"-living cells that have stopped dividing or functioning normally-but linger in our tissues, contributing to chronic inflammation and age-related diseases.

6 Oct 2026

Targeting Host Cellular Repair Mechanisms Enhances Tissue Resistance to Infection

Epithelial cells form the body's frontline barriers, helping keep microbes, toxins, and other harmful substances out. Yet these protective cells are constantly exposed to threats, including microbial infections.

6 Oct 2026

Research Consortium Maps Mitochondrial Diversity Across the Complex Tree of Life

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life.

5 Oct 2026

Researchers Discover Key Protein Mechanism Enabling Fungal Drug Resistance

The battle lines have finally shifted in the war against a deadly fungal disease.

5 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

OCT News and Research

Researchers Capture Real-Time Molecular Movie of Penicillin Enzymatic Ring Closure

Study Creates Global Single-Cell Map of Human Immune System Aging

Microbe Retains Self-Replication Machinery While Discarding Almost All Metabolic Pathways

Granular Genetic Risk Prediction Enables Early Detection of Hearing Loss

Transposable Element Methylation Instability Impairs Overall Genomic Regulation in Large Breeds

Retrotransposon Reactivation Suggests Reverse Transcriptase Inhibitors Lower Cancer Risk

Ten Shared Gene Clusters Map Common Immune Response Pathways Across Diseases

Studies Redefine Lactation Biology Through Computational Multi-Omics and Mammary Metabolic Modeling

Prime Editing Generates Genomic Ticker Tapes Tracing Millions of Developing Cells

Genetic Analysis of Spotted Bats Traces Evolution Across Time

Ancient Gut Microbes Traveled Globally With Prehistoric Human Ancestors

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Aldabra Giant Tortoise Genome Provides Evolutionary Blueprint for Cellular Resilience

Mitochondrial Genome Dynamics Influence Intrinsic Tumor Aggressiveness

Ancient DNA Reveals Extinct Bovine Species in Southern Siberia

Undigested Cellular Waste Secretes Toxic Signals That Zombify Surrounding Tissue

Targeting Host Cellular Repair Mechanisms Enhances Tissue Resistance to Infection

Research Consortium Maps Mitochondrial Diversity Across the Complex Tree of Life

Researchers Discover Key Protein Mechanism Enabling Fungal Drug Resistance

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

RecentIndustryFocuses

Editorial Focus eBook - Biopharmaceuticals (2nd edition)

Improving Cell Culture Efficiency with Image-Guided Automation

Improving Scalability in Organoid Research

Cosmetic Formulation and Manufacturing

Latest in Genomics