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New Lipid Nanoparticles Deliver mRNA for Lung Tissue Regeneration

New research from the Perelman School of Medicine at the University of Pennsylvania suggests that a combination of messenger RNA (mRNA) and a novel lipid nanoparticle (LNP) could potentially be used to repair lung damage.

24 Feb 2025

New 3D Lung Model Offers Personalized Aerosol Therapeutic Insights

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.

21 Feb 2025

New Discoveries Challenge Textbook Knowledge of Mitochondrial Respiration

In an article published in the journal Trends in Biochemical Sciences, Alicia Kowaltowski, full professor at the University of São Paulo's Institute of Chemistry (IQ-USP) in Brazil, advocates the "rewriting" of textbooks on the location of the electron transport chain in mitochondria and the role of sodium in mitochondrial respiration.

20 Feb 2025

Mitochondrial Transfer Uncovered as Key Player in Cancer Immune Evasion

The immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.

12 Feb 2025

New Study Explains Why Flu Virus Forms Filaments

Influenza A virus particles strategically modify their shape becoming either spheres or larger filaments to enhance their ability to infect cells based on environmental conditions, according to a new study conducted by scientists at the National Institutes of Health (NIH).

11 Feb 2025

Coffee's Bitter Taste Linked to Genetics and Roasting Process

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

30 Jan 2025

New Microfluidic Device can Detect SARS-Cov-2 with Revolutionary Sensitivity

VirusHB-Chip offers groundbreaking sensitivity in detecting SARS-CoV-2 in plasma, saliva, and stool, transforming COVID-19 diagnostics and treatment strategies.

30 Jan 2025

New Consensus Paper Advances Nomenclature for Mitochondria Transfer and Transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

28 Jan 2025

New Insights into the Structure and Function of a Key Viral Protein

Researchers at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a crucial part of the Nipah virus, a deadly bat-borne infection that has been responsible for human outbreaks every year since its discovery in 1999.

21 Jan 2025

Is it possible to predict a pathogen’s next move? Novel tool for detecting pathogen fitness says yes!

Phylowave reveals evolutionary dynamics in pathogens, identifying fitness-linked lineages and mutations, essential for effective public health interventions.

13 Jan 2025

Multi-Site Effort to Understand Viral Influences on Human Health

For more than ten years, researchers have been investigating the microbiome, the ecosystem of microorganisms that inhabit the body, and its impact on health and disease.

10 Jan 2025

Deadly Mould Strains Highly Likely to Acquire Resistance to New Drugs

Scientists have identified strains of one of the world’s most dangerous fungal pathogens, already resistant to our most effective antifungal drugs, which are also 5-times more likely to acquire resistance to desperately needed new treatments in development.

From The University of Manchester 16 Dec 2024

Lice as Models for Studying Mitochondrial Disorders

A set of genes that in humans would suggest a late-stage degenerative disease like Parkinson’s or Alzheimer’s disease are present in lice throughout their lives.

10 Dec 2024

ENOD93 Linked to Mitochondrial Function and Nitrogen Efficiency in Plants

The protein ENOD93 regulates mitochondrial respiration and energy production in Arabidopsis, highlighting its role in nitrogen metabolism and plant development.

6 Dec 2024

LysoTRAP Strategy Offers Hope for Clearing Viral Infections Across Variants

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences have recently developed a novel lysosomal strategy for clearing viruses and their variants.

28 Nov 2024

Study Links MICOS10 Gene Defect to Mitochondrial DNA Depletion Syndrome

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA).

27 Nov 2024

Novel Genetic Variant Associated with Severe Mitochondrial Dysfunction

The rare hereditary condition known as mitochondrial DNA depletion syndrome (MTDPS) is typified by a significant reduction in mitochondrial DNA (mtDNA).

26 Nov 2024

SARS-CoV-2 Outwits Immune System, Prolonging Infection

SARS-CoV-2 inhibits the function of the complement system, a crucial element of early antiviral immunity, by hijacking three crucial host proteins, according to research from the Medical Universities of Vienna and Innsbruck.

11 Nov 2024

A New Understanding of Viral Infection

Scientists studying animal viruses with the potential to infect humans have discovered a critical protein that could facilitate the spread of a family of organisms known as arteriviruses.

1 Nov 2024

The Dangers of Zoonotic Diseases

According to a recent study published in Nature, mice and ferrets infected in a high-containment laboratory setting died from a highly pathogenic avian influenza (HPAI) H5N1 virus that was isolated from the eye of a farm worker who contracted the virus from contact with dairy cows.

29 Oct 2024