Immunotherapy News and Research

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Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

Combination treatment improves outcomes in advanced kidney cancer patients

An immunotherapy agent combined with a tyrosine kinase inhibitor drug significantly improved progression-free survival and reduced the risk of death compared to a single agent treatment in advanced kidney cancer patients, according to first results of a phase 3 clinical trial. The pivotal study could lead to a new treatment option for patients with metastatic kidney cancer.

24 Sep 2020

New Dual CAR T cell immunotherapy can help fight against HIV infection

A recent study published in the journal Nature Medicine, led by researchers James Riley, PhD, a professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, and Todd Allen, PhD, a professor of Medicine at Harvard Medical School and Group Leader at the Ragon Institute of MGH, MIT and Harvard, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection

24 Sep 2020

Study helps explain how Treg cells prevent autoimmunity, dampen immune responses

In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

22 Sep 2020

Elderly patients face higher risk of severity and death from COVID-19

SARS-CoV-2 can infect people of any age. However, elderly people face a greater risk of severity and death when compared to younger patients.

22 Sep 2020

New methods to increase anti-cancer activity of T cells

Scientists have gained a deeper insight into the complexity of the surrounding in which T cells flourish.

18 Sep 2020

Mathematical model can determine the impact of immune system on tumor evolution

Researchers at Queen Mary University of London, The Institute of Cancer Research, London, and the Moffitt Cancer Centre have created a mathematical model that can determine the impact of the immune system on tumor evolution.

17 Sep 2020

In-depth study of kidney tumors reveals novel markers of response to immunotherapy

Treatments for kidney cancer have improved considerably over the past few decades. In 1988, when Memorial Sloan Kettering oncologist Robert Motzer started researching the disease, the average survival was less than one year.

9 Sep 2020

Researchers discover the developmental process of strong immune T-cells

There are memory cells that remember previously encountered pathogens and help to react quickly and strongly when exposed to them again.

4 Sep 2020

Researchers discover the developmental process of novel immune T cells

Memory cells essentially recall formerly encountered pathogens and help respond strongly and rapidly when they are exposed to this foreign matter again.

3 Sep 2020

New study shows how tumor cells evade the immune system

If cancer is a series of puzzles, a new study pieces together how several of those puzzles connect to form a bigger picture.

3 Sep 2020

Natural killer cells could be a powerful weapon for fighting lung cancer

Immune cells called 'natural killer' (NK) cells could be a powerful weapon for fighting lung cancer, according to Australian researchers.

2 Sep 2020

Researchers identify an effective treatment for severe cases of COVID-19 infection

Scientists are trying to figure out how SARS-CoV-2 leads to a range of symptoms that appear to persist long after the active viral infection.

From Osaka University 1 Sep 2020

New 3D hydrogels show promise in cancer immunotherapy

A group of researchers have developed new hydrogels that make it possible to culture T lymphocytes or T cells found in the immune system.

1 Sep 2020

Researchers identify mechanisms that impair the immune system in response to viral infections

Scientists have discovered mechanisms that cause functional deterioration of the immune system in reaction to viral infections, including COVID-19 or HIV.

26 Aug 2020

STING protein activates a pathway that kills tumor-fighting immune cells

The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule. Now, UT Southwestern scientists have revealed that STING also activates a separate pathway, one that directly kills tumor-fighting immune cells.

25 Aug 2020

Researchers add a component to make cancer vaccine more effective

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

25 Aug 2020

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors

21 Aug 2020

A metabolic enzyme could be potential target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

21 Aug 2020

Newly developed transplantable human cells can help cure type 1 diabetes

Researchers have made a significant advancement in the quest for a safe, effective treatment for type 1 diabetes.

20 Aug 2020

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020