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Study reveals how a fly’s brain contributes to sensing the cold and limiting reproduction

Scientists have uncovered a set of neurons in fruit flies that shut down in cold temperatures and slow reproduction, a system conserved in many insects, including mosquitoes, which could provide a target for pest control.

18 Feb 2022

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

New research co-led by a University of Ottawa Faculty of Medicine professor is shedding light on some of the mysterious dynamics that define the interplay between nerves and muscle.

17 Feb 2022

Novel immune deactivation pathway offers a promising therapeutic approach for cancers

Our immune systems have the potential to find and destroy cancer cells. But cancer cells can be clever and develop tricks to evade the immune system.

17 Feb 2022

CRISPR/Cas9-mediated gene editing is now feasible in ticks

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field.

17 Feb 2022

Study highlights how IL-2 regulates developmental bifurcation

The immune system is a complicated network of cells and proteins that performs a straightforward function—protecting the body against infection.

15 Feb 2022

Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Antibody-drug conjugates, an intricate that covalently links a potent cytotoxin to an antibody, have piqued the interest of researchers as a new bio-therapeutic methodology.

14 Feb 2022

Hemoglobin plays role as a chemosensory signal for mother mice to protect offspring

Biochemists in Japan were surprised to discover that the molecule hemoglobin in the blood works not only as an oxygen carrier, but when the blood is spilled as a result of aggression, accident or predator attack, the molecule also acts as a chemosensory signal -; a chemical stimulus picked up by the senses, namely smell in this case -; for lactating mother mice, prompting digging or rearing behavior in them to check the surrounding environment and keep their offspring safe.

11 Feb 2022

Three proteins as potential new therapeutic targets in movement disorders

Three members of a family of proteins have been identified that are important to helping us fine tune the activity of brain chemicals which enable us to walk or stand at will, scientists report.

11 Feb 2022

Tropical sea anemone stings could hold key to new pain-relieving drugs

QUT PhD researcher Lauren Ashwood has studied sea anemones' venom makeup extensively, in particular, Telmatactis stephensoni a reef-based sea anemone that can grow from 8 to 10 cm.

8 Feb 2022

Largest genome study identifies new genetic risk factors for migraine

An international consortium of leading migraine scientists identified more than 120 regions of the genome that are connected to risk of migraine.

4 Feb 2022

Research highlights how carnosic acid found in rosemary inhibits SARS-CoV-2 infection

Scripps Research scientists have discovered evidence that a chemical present in rosemary might be a two-pronged weapon against SARS-CoV-2.

4 Feb 2022

Researchers build rapid-acting antidepressant compounds that are non-hallucinogenic

The World Health Organization estimates that nearly 280 million people worldwide suffer from depression.

2 Feb 2022

Study shows how shuttle proteins safeguard the nuclear pores

The nucleus is guarded by a highly secure door, the so-called nuclear pore, that controls the transport of substances from the cytoplasm to the cell nucleus and back.

1 Feb 2022

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

A University of South Florida Health (USF Health) preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

1 Feb 2022

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.

From Society for Laboratory Automation and Screening (SLAS) 27 Jan 2022

COVID-19 vaccines prompt the body to make long-lasting T cells against different variants

Scientists at La Jolla Institute for Immunology (LJI) have found that four COVID-19 vaccines (Pfizer-BioNTech, Moderna, J&J/Janssen, and Novavax) prompt the body to make effective, long-lasting T cells against SARS-CoV-2.

25 Jan 2022

Immune cells in arteries can sniff out their surroundings and cause inflammation

An artery is not like a nose. Or is it? Scientists at La Jolla Institute for Immunology (LJI) have discovered that immune cells in arteries can "sniff" out their surroundings and cause inflammation.

17 Jan 2022

Researchers identify new potential drug target that may block SARS-CoV-2 infection

In the quest for new treatments for COVID-19, a team led by researchers at UC San Francisco has identified a new potential drug target that may block infection by SARS-CoV-2. The protein, called BRD2, regulates the ACE2 receptor, which the novel coronavirus relies on to gain entry to its host's cells.

17 Jan 2022

Moffitt researchers unravel the role of B cells in endometrial cancer

Endometrial cancer is the most common cancer of the female reproductive system. Patients who have active immune responses against cancer cells tend to have better outcomes, but much of what is known focuses on only one type of immune cell called T cells.

13 Jan 2022

Latest tools for COVID-19 Omicron variant research

AMSBIO has announced new additions to its portfolio of tools for COVID-19 research - two monoclonal antibodies that recognize the Spike RBD (B.1.1.529, Omicron Variant) protein and neutralizes its interaction with ACE2.

From AMS Biotechnology 11 Jan 2022

Receptor News and Research

Study reveals how a fly’s brain contributes to sensing the cold and limiting reproduction

Cryo-electron microscopy reveals structures of a muscle-type nicotinic acetylcholine receptor

Novel immune deactivation pathway offers a promising therapeutic approach for cancers

CRISPR/Cas9-mediated gene editing is now feasible in ticks

Study highlights how IL-2 regulates developmental bifurcation

Researchers develop a simple and effective strategy to synthesize site-specific antibody–drug conjugates

Hemoglobin plays role as a chemosensory signal for mother mice to protect offspring

Three proteins as potential new therapeutic targets in movement disorders

Tropical sea anemone stings could hold key to new pain-relieving drugs

Largest genome study identifies new genetic risk factors for migraine

Research highlights how carnosic acid found in rosemary inhibits SARS-CoV-2 infection

Researchers build rapid-acting antidepressant compounds that are non-hallucinogenic

Study shows how shuttle proteins safeguard the nuclear pores

Study offers insight into how activated protein C may protect aging patients from reperfusion injury

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

COVID-19 vaccines prompt the body to make long-lasting T cells against different variants

Immune cells in arteries can sniff out their surroundings and cause inflammation

Researchers identify new potential drug target that may block SARS-CoV-2 infection

Moffitt researchers unravel the role of B cells in endometrial cancer

Latest tools for COVID-19 Omicron variant research

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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