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Integrative Genomic Approaches Reveal Mechanisms of Garlic Storability

Garlic (Allium sativum L.) is one of the world's most widely consumed spices and health supplements, with China producing 80% of the international supply.

22 Sep 2025

Novel Chromosome Identification System Overcomes Longstanding Bottleneck in Alfalfa Cytogenetics

Karyotype analysis is fundamental to understanding genetic makeup, diversity, and adaptation in plants. Yet, distinguishing individual chromosomes remains challenging in species with small, uniform chromosomes and complex polyploid genomes such as alfalfa.

22 Sep 2025

Modified Cas9 Proteins Dramatically Lower Error Rates in Prime Editing

A genome-editing technique known as prime editing holds potential for treating many diseases by transforming faulty genes into functional ones.

18 Sep 2025

Carbon Starvation Drives Metabolic and Epigenetic Reprogramming in Grapevine Cells

Plants rely on sugars not only as energy sources but also as regulators of cellular activities. Carbon starvation disrupts central metabolism, impairs growth, and forces cells to recycle stored resources.

18 Sep 2025

The First Parent-Of-Origin Gene Atlas of The Mammary Gland

This study maps dynamic gene expression in mouse mammary glands, revealing insights into lactation, maternal health, and breast cancer risk through imprinting.

18 Sep 2025

Discovery of R-Loops Reveals Key Vulnerability in HIV-1 Life Cycle

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome.

17 Sep 2025

CRISPR Breakthrough Makes Cacao Plants More Resistant To Deadly Disease

This study shows CRISPR-Cas9 modifications to the TcNPR3 gene in cacao reduce Phytophthora susceptibility, supporting eco-friendly agricultural practices.

17 Sep 2025

Soil DNA Reveals Hundreds of Unknown Bacterial Genomes

Most bacteria cannot be cultured in the lab-and that's been bad news for medicine. Many of our frontline antibiotics originated from microbes, yet as antibiotic resistance spreads and drug pipelines run dry, the soil beneath our feet has a vast hidden reservoir of untapped lifesaving compounds.

16 Sep 2025

Cheesemaking Inspires New Insights into Fungal Evolution and Food Security

Many scientific discoveries are serendipitous-the result of chance. Seeing evolution in action in a cheese cave turned out to be exactly that for Benjamin Wolfe, associate professor of biology, and his colleagues.

15 Sep 2025

Researchers Decipher the Rules Behind Cellular Quality Control In Humans

A research team at the University of Cologne and the Max Delbrück Center in Berlin has deciphered in detail the rules behind an important mechanism of cellular quality control in humans.

13 Sep 2025

Engineered Base Editor Corrects ACTA2 Mutation in Rare Childhood Disease

Multisystemic smooth muscle dysfunction syndrome (MSMDS) is a rare condition associated with stroke, aortic dissection (tearing) and death in childhood.

13 Sep 2025

New Genomic Analysis Platform Launched for Tracking for Zoonotic Pathogens

Zoonotic pathogens, capable of crossing between animals and humans, pose escalating threats due to antimicrobial resistance, genetic diversification, and complex transmission patterns.

11 Sep 2025

Researchers Discover Giant DNA Elements Hidden in the Human Mouth

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection.

10 Sep 2025

Genome-Wide Study Connects Human Genetic Variation to Mycobiome Diversity and Disease

A new genome-wide study uncovers evidence of the first three-way relationships between human genetic variation, variation in the fungal component of the human microbiome - known as the mycobiome - and risk of developing chronic disease.

10 Sep 2025

New Method Discovers Genetic Switches More Quickly

Researchers led by Dubravka Vučićević at the Max Delbrück Center have developed a new method for discovering how DNA controls genes. Published in “Cell Genomics,” their technique can reveal the genetic “switches” that regulate important genes more quickly than existing methods.

10 Sep 2025

Tracing Origins of Wnt Signaling Through the Lipocone Superfamily

Researchers have described a large set of previously unrecognized enzymatic domains – named the Lipocone superfamily – and outlined their evolutionary pathway from bacterial defense molecules to key players in human development.

10 Sep 2025

spVelo: A New Method for Integrating Spatial and Temporal Data in RNA Velocity Analysis

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it will be and its function.

8 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

Discovery of De Novo Genes Sheds Light on Peach Evolution and Traits

The emergence of new genes is a central driver of evolutionary innovation. While mechanisms such as duplication and horizontal gene transfer have been widely studied, de novo gene birth represents a unique pathway where functional genes arise from noncoding DNA.

8 Sep 2025

Ancient Plant Protein Unlocks New Strategy for Engineering Disease-Resistant Crops

Researchers led by Ken Shirasu at the RIKEN Center for Sustainable Resource Science (CSRS) in Japan have identified an ancient protein that has the potential to help defend plants against tens of thousands of different bacteria and other pathogens.

5 Sep 2025