Genome News and Research

RSS

Breakthrough Study Identifies Unique Breast Cancer Genes in South African Women

Genetic factors contribute to some 30% of breast cancer cases in SA, necessitating investment in genomic research in African contexts.

16 May 2025

Scientists Develop EvoCAST for Efficient and Accurate Gene Insertion

Ask scientists what gene editing tool is most needed to advance gene therapy, and they'd probably describe a system that's now close to realization in the labs of Samuel Sternberg at Columbia University Vagelos College of Physicians and Surgeons and David Liu at the Broad Institute of MIT and Harvard.

16 May 2025

Real Time RNA Tracking in Plants Using Fluorescent Biosensors

RNA acts as a messenger inside cells, carrying instructions from DNA that are translated into proteins that are essential for how cells function.

15 May 2025

Variance Analysis Enhances Genetic Risk Prediction for Blood Cell Traits

A Nature Communications study shows that incorporating variance polygenic scores (vPGS) and variance QTLs (vQTLs) improves genetic risk prediction for blood-related diseases, offering new insight into phenotype variability and lifestyle factors like alcohol intake.

15 May 2025

Novel Role for Disordered Protein in Coordinating Key Stages of Gene Expression

Research reveals TAF2's disordered region links transcription and RNA editing, highlighting its role in gene expression regulation and nuclear organization.

15 May 2025

Viral circRNAs Sponge Up Host miRNAs to Weaken Immune Response

In a significant breakthrough, researchers from Florida Atlantic University’s Charles E. Schmidt College of Medicine have uncovered a previously unknown mechanism that allows the human immunodeficiency type 1 virus (HIV-1) to evade the body’s natural defenses, thereby facilitating its survival and replication.

14 May 2025

DiffInvex Reveals Genetic Escape Routes Used by Tumors Against Treatment

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer.

14 May 2025

Danforth Technology Company Backs Startup Transforming Crop Genetics

The Danforth Technology Company (DTC) today announced the launch of Spearhead Bio, a startup pioneering a breakthrough platform to enhance the efficiency of crop genome engineering by harnessing the plant's own natural DNA.

14 May 2025

Unraveling How E. histolytica Kills Cells and Evades the Immune System

Understanding how E. histolytica attacks human cells and evades immunity is crucial for developing effective treatments and vaccines against this parasite.

13 May 2025

Unraveling the Genetic Basis of Biosurfactant Production in an Oil-Degrading Bacterium

The marine bacterium Alcanivorax borkumensis consumes oil and proliferates rapidly following oil spills, thereby enhancing the removal of pollution in many instances.

12 May 2025

Grapevine Cells Show Epigenetic Shifts in Response to Sugar Starvation

Plants face constant challenges from fluctuating nutrient availability, which disrupts their growth and survival.

10 May 2025

Scientists Unlock Microbial Stress Responses with Advanced Gene Silencing

Scientists at Oak Ridge National Laboratory and the University of Colorado Boulder used a gene-silencing tool and a large library of molecular guides to understand how photosynthetic bacteria adapt to light and temperature changes.

10 May 2025

AI Designs Synthetic DNA to Control Gene Expression in Mammalian Cells

A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

10 May 2025

Grapevine Cells Reveal Epigenetic Response to Sugar Starvation

Plants face constant challenges from fluctuating nutrient availability, which disrupts their growth and survival.

6 May 2025

Role of LADs and Epigenetic Pathways in Nuclear Architecture During Early Mouse Embryo Development

A new study in Cell reveals that lamina-associated domains (LADs) in early mouse embryos are shaped by dynamic epigenetic pathways, highlighting how histone modifications and chromatin structure guide nuclear architecture during development.

6 May 2025

Evolutionary Rescue in Microbes Leads to the Collapse of Mutualism

Microorganisms –defined as very small living beings, invisible to the naked eye, comprising bacteria, fungi, viruses or others– naturally compete and cooperate in nature for survival.

5 May 2025

New Gene Editing Tool Alters Mitochondrial Mutation Levels in Stem Cells

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.

5 May 2025

Dr. Jeremy Poschmann’s data-driven approach to immune profiling and translational science

Dr. Jeremy Poschmann discusses data-driven approaches in genomics, revealing how immune profiling can predict disease risk and improve patient outcomes.

1 May 2025

Genetic Diversity in Wild Rice Offers Clues for Crop Improvement

A new study, seen in Nature Genetics and led by researchers at King Abdullah University of Science and Technology (KAUST; Saudi Arabia) and Wageningen University & Research (the Netherlands), provides new insights on rice evolution, showing how the DNA of this valuable crop has changed across species.

29 Apr 2025

New Pangenome Analysis Uncovers Genetic Key to Larger Peanut Yields

Researchers from Australia and China have identified crucial structural variations that determine seed size and weight in peanuts, paving the way for the development of higher-yielding crop varieties.

29 Apr 2025