therapeutics News and Research

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Salk Scientists Use CRISPR to Uncover Microproteins Linked to Obesity

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide.

8 Aug 2025

Sugarcoated RNA Helps the Body Avoid Autoimmune Reactions

To our immune system, naked RNA is a sign of a viral or bacterial invasion and must be attacked. But our own cells also have RNA.

7 Aug 2025

Gut Bacteria Breakthrough Could Help Fight Chronic Diseases

An international research team led by scientists from the University of Copenhagen has discovered a common gut bacterium that lowers body weight and blood sugar while increasing bone density.

1 Aug 2025

New Computer Program Mimics Human and Animal Cell Behavior

Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body.

28 Jul 2025

Elegen and Nutcracker Therapeutics to Pilot First Fully Cell-Free Manufacturing Process for RNA-based Personalized Cancer Therapeutics

Elegen, a global leader in next-generation DNA manufacturing, and Nutcracker Therapeutics, a global leader in next-generation RNA design and manufacturing, today announced the launch of a pilot program to demonstrate the industry's first fully synthetic, cell-free manufacturing platform for RNA-based personalized cancer therapeutics (PCTs).

From Elegen 15 Jul 2025

Vanderbilt and Parse Biosciences Join Forces to Accelerate Measles Antibody Discovery

Vanderbilt University Medical Center and Parse Biosciences, an innovator in single-cell sequencing, are collaborating on a new treatment to help unvaccinated measles victims, as the U.S. measles outbreak has now reached its highest case count in 30 years.

9 Jul 2025

New Software Boosts Genome Editing Accuracy for Genetic Therapies

This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders and uncharacterized peptides.

9 Jul 2025

New Stem Cell Reports Perspective: Biomanufacturing in Low Earth Orbit

A new perspective article just published in Stem Cell Reports, “Biomanufacturing in low Earth orbit: A paradigm shift,” features insights from the ISS National Laboratory’s very own Program Director for In-Space Biomanufacturing Davide Marotta, Deputy Chief Scientist Donna Roberts, and Chief Scientist Michael Roberts, as well as leading researchers in regenerative medicine.

3 Jul 2025

Combining AI with Robotics and Synthetic Biology to Improve Industrial Enzymes

By combining artificial intelligence with automated robotics and synthetic biology, researchers at the University of Illinois Urbana-Champaign have dramatically improved performance of two important industrial enzymes - and created a user-friendly, fast process to improve many more.

2 Jul 2025

ColdBrew Enhances Accuracy of Protein Water Mapping for Drug Design

Every protein in the body is encased in a water shell that directs protein structure, provides vital stability and steers function.

30 Jun 2025

New Study Maps How Pesticides Alter Human Gut Bacteria

While emerging evidence suggests pesticides can be toxic to the mix of microorganisms in the digestive system, a new study is the first to map changes to specific gut bacteria based on interactions between human microbes and insect-killing chemicals observed in the lab and an animal model.

30 Jun 2025

Tracing the Genetic Mosaic of India Through Ancient Ancestry and Modern Genomes

India's population is genetically one of the most diverse in the world, yet it remains underrepresented in global datasets.

27 Jun 2025

RNases Play Pivotal Role in Shaping the Molecular Foundation of Mendelian Disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Fusion Genes Emerge as Key Drivers in Cancer Development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025

UT Southwestern Researchers Develop Multi-Organ Gene Editing Strategy

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

23 Jun 2025