Drugs News and Research

RSS

PD-1 Guides T Cells to Become Long-Term Immune Defenders in the Skin

Weill Cornell Medicine researchers have discovered that PD-1—a molecule best known for putting the brakes on immune cells—also plays a critical role in helping T cells become long-term immune defenders in the skin.

30 Jul 2025

Stability in Proteins Is More Like Lego Than Jenga

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses.

29 Jul 2025

Gene Editing Offers New Hope to Stop Malaria Transmission

Mosquitoes kill more people each year than any other animal. In 2023, the blood-sucking insects infected a reported 263 million people with malaria, leading to nearly 600,000 deaths, 80% of which were children.

24 Jul 2025

New Insights into How Cilia Move and Power Cellular Motion

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

23 Jul 2025

Misfolded Proteins in Mitochondria Linked to Type 2 Diabetes

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding.

23 Jul 2025

OHSU Team Identifies Gene Essential for Brain's Protective Layer

Researchers at Oregon Health & Science University have discovered a gene that is critical to the brain’s ability to form myelin, a protective layer around nerves, potentially leading to new treatments for an extremely uncommon childhood disorder and more common diseases such as multiple sclerosis.

23 Jul 2025

Chemists Discover Safer Way to Create Powerful Chemical Building Blocks

Chemists have developed a novel way to generate a variety of highly useful chemical building blocks by harnessing metal carbenes, suggests new research.

21 Jul 2025

mRNA Vaccine Supercharges Immunotherapy Against Cancer

An experimental mRNA vaccine improved the tumor-fighting benefits of immunotherapy in a mouse model study, bringing researchers one step closer to their aim of generating a universal vaccination to “wake up” the immune system against cancer.

21 Jul 2025

Amino Acids Guide Cell Responses to Drugs Through a Complex Network

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like bricks that communicate with each other within a structure.

17 Jul 2025

Study Reveals Surprising Redundancy in Staph Metabolism

In the ongoing battle against antibiotic-resistant bacteria, MSU researchers have made a discovery that could reshape how we target deadly pathogens like staph infections.

17 Jul 2025

Candida Auris Uses Distinct Defense Mechanism to Survive Antifungal Treatments

A groundbreaking study from Michigan State University (MSU), recently published in Nature Communications, has revealed how the multidrug-resistant superfungus Candida auris uniquely reconstructs its cell wall to survive antifungal treatments.

16 Jul 2025

Researchers Uncover Complex Substrate Profile for Enzyme Action

Research on γ-secretase reveals its unique substrate recognition mechanism, offering potential for developing precise therapeutic agents for various diseases.

14 Jul 2025

New Cellular Signature Reveals Why Some Prostate Cancers Resist Standard Treatment

A new study from University of Michigan Rogel Cancer Center researchers identifies a cellular signature that explains why about one-third of prostate cancers respond especially poorly to treatment.

9 Jul 2025

New Software Boosts Genome Editing Accuracy for Genetic Therapies

This innovative software, CRISPRware, optimizes guide RNA design for genome editing, supporting research on genetic disorders and uncharacterized peptides.

9 Jul 2025

New Insights into Cell Membrane Energy Waves

Johns Hopkins researchers identify energy-generating waves on cancer cell membranes, revealing potential targets for slowing tumor growth and spread.

9 Jul 2025

Evidence for Neural Stem Cell-Based Therapies in Multiple Sclerosis

Research indicates that neural stem cell transplants could promote myelin repair in progressive multiple sclerosis, paving the way for innovative treatments.

8 Jul 2025

New Stem Cell Reports Perspective: Biomanufacturing in Low Earth Orbit

A new perspective article just published in Stem Cell Reports, “Biomanufacturing in low Earth orbit: A paradigm shift,” features insights from the ISS National Laboratory’s very own Program Director for In-Space Biomanufacturing Davide Marotta, Deputy Chief Scientist Donna Roberts, and Chief Scientist Michael Roberts, as well as leading researchers in regenerative medicine.

3 Jul 2025

Understanding the Bacterial Propeller Architecture Offers Hope Against Antibiotic Resistance

Scientists have studied a new target for antibiotics in the greatest detail yet – in the fight against antibiotic resistance.

2 Jul 2025

Fidelio Capital Partners with Alphalyse to Accelerate the Global Roll-Out of LC-MS Host Cell Protein Analytics

Alphalyse, a fast-growing Danish specialist contract research organization (CRO) that has developed GMP‑validated liquid‑chromatography mass‑spectrometry (LC‑MS) assays for host‑cell‑protein (HCP) impurity testing in biologic drugs, today announces that Fidelio Capital has acquired a majority stake in the company.

From Alphalyse A/S 2 Jul 2025

Fusion Genes Emerge as Key Drivers in Cancer Development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025