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Stanford Researchers Find a Molecule That Rivals Ozempic in Weight Loss

BRP emerges as a promising peptide for weight loss, activating appetite control pathways without triggering nausea, paving the way for safer obesity therapies.

17 Mar 2025

Mitochondria Found to Control DNA Repair Protein and Delay Inflammaging

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

14 Mar 2025

Study Reveals How DNA Reorganization Helps Cells Survive UV Damage

Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer.

13 Mar 2025

Molecular Intelligence Simplifies Cryo-EM Data Analysis with AI

Scientists from Purdue University’s College of Science and the Rosen Center for Advanced Computing have established Molecular Intelligence, a software company dedicated to assisting researchers in determining the 3D structures of biomolecules captured through cryogenic-electron microscopy (cryo-EM).

13 Mar 2025

New Cannabinoid Drug Brings Hope For Treating Chronic Pain Without Addiction

VIP36, a new CB1 agonist, targets a cryptic pocket to provide analgesia for chronic pain while minimizing side effects and avoiding opioid-related risks.

13 Mar 2025

Researchers Create 'Colocatome' to Study Tumor Cell Interactions

Even cells experience peer pressure. Scientists have long studied the ins and outs of cancer cells to learn more about the disease, but they're increasingly finding that noncancerous cells near the cancer cells exert a powerful influence over a tumor's trajectory.

13 Mar 2025

Cryo-EM Reveals 3D Structure of Nipah Virus RNA Polymerase

The replication of the Nipah virus's genetic material in infected cells has been demonstrated for the first time by researchers from the Max Planck Institute (MPI) for Multidisciplinary Sciences and the University Medical Center Göttingen (UMG). In humans, the virus can cause fatal encephalitis.

11 Mar 2025

Investigating Ubiquitination's Role in Cancer Stem Cell Regulation

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

10 Mar 2025

Tumour-on-Chip Model Supports Preclinical Drug Development on Pancreatic Cancer

The biotech company Dynamic42, a specialist in organ-on-chip technology, has made a significant advance in pancreatic cancer drug research in collaboration with the research team of Prof. Dr. Nicole Teusch at the Institute of Pharmaceutical Biology and Biotechnology at Heinrich Heine University Düsseldorf.

7 Mar 2025

Discovery of Ball-and-Chain Mechanism Sheds Light on Ion Channel Regulation

A new study has unveiled a precise picture of how an ion channel found in most mammalian cells regulates its own function with a "ball-and-chain" channel-plugging mechanism, according to investigators at Weill Cornell Medicine.

5 Mar 2025

Synthetic Microbiome Treatment Prevents C. difficile Infection in Mice

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

4 Mar 2025

New CRISPR Method Enhances Surveillance of Antibiotic Resistance in Wastewater

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections in humans and animals.

4 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

Gut Microbes Transform Excreted Glucose into Crucial Fatty Acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

New Cancer-on-Chip Tech Could Replace Animal Testing—Faster, Cheaper, More Accurate!

A new modified silicone rubber for cancer-on-chip applications improves cell adhesion and drug testing, paving the way for personalized cancer treatments.

28 Feb 2025

Age-Invariant Genes May Hold the Key to Understanding Aging and Longevity

A new research paper was published in Aging (Aging-US) on January 27, 2025, in Volume 17, Issue 1, titled "Age-invariant genes: multi-tissue identification and characterization of murine reference genes."

27 Feb 2025

Innovative Screening Method Targets Specific Tissues for Drug Delivery

A method developed by a research group at Tampere University seeks specific molecules that can target desired tissues through the bloodstream and penetrate tissues by passing through cells.

27 Feb 2025

New Lipid Nanoparticles Deliver mRNA for Lung Tissue Regeneration

New research from the Perelman School of Medicine at the University of Pennsylvania suggests that a combination of messenger RNA (mRNA) and a novel lipid nanoparticle (LNP) could potentially be used to repair lung damage.

24 Feb 2025

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

22 Feb 2025