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Animal Testing to Be Phased Out Faster as UK Unveils Roadmap for Alternative Methods

Animal testing in science is set to be phased out faster under a new plan to deliver on the government’s manifesto commitment, unveiled by Science Minister Lord Vallance today (Tuesday 11 November).

13 Nov 2025

Brain Immune Cells Found to Act as Accelerators and Brakes for Anxiety

Anxiety disorders are some of the most common mental health conditions in America, affecting about one in five people nationwide.

12 Nov 2025

AlphaSync Brings Continuous Updates to Global Protein Structure Predictions

The shape, or structure, of proteins determines how they work, making it essential for researchers to have access to high-quality structural models.

12 Nov 2025

Rare Stress-Sensitive Neurons Hold the Key to Healthy Brain Blood Flow

While the exact causes of neurodegenerative brain diseases like Alzheimer's and dementia are still largely unknown, researchers have been able to identify a key characteristic in affected brains: reduced blood flow.

12 Nov 2025

CellWhisperer Enables Natural Language Exploration of Single-Cell Biology

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

12 Nov 2025

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

New Tool Merges Ex-Vivo and In-Vivo Brain Data for White Matter Research

BraDiPho is an innovative tool for the study of white matter connections in the human brain. A realistic map developed by a group of researchers from the University of Trento, the Provincial Healthcare Service of Trento, Fondazione Bruno Kessler and the Universities of Bordeaux and Sherbrooke.

7 Nov 2025

Scientists Reveal Nonenzymatic Role of NUDT5 in Purine Pathway Regulation

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.

7 Nov 2025

Transforming Stomach Cells into Insulin Factories for Diabetes Treatment

Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide.

7 Nov 2025

Atomic Structure of Kinesin-2 Reveals the Molecular Logic of Cargo Recognition

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells.

7 Nov 2025

Decoding DNA’s Spatial Organization With Precision Tools

DNA is more than simply a lengthy string of genetic code; it is a complex three-dimensional structure folded inside each cell. That means that the equipment used to examine DNA must be as sophisticated, capable of reading not just the code itself but also its spatial arrangement.

7 Nov 2025

Oxidative Stress May Hold Clues to the Origins of Repetitive Behaviors

Abnormal repetitive behaviors in mice are strongly linked to multiple biomarkers of oxidative stress, which occurs when antioxidants cannot counteract the effects of harmful molecules in the body, according to a study published November 5, 2025, in the open-access journal PLOS One by Kendall Coden and Dr. Joseph Garner of Stanford University, U.S.

6 Nov 2025

Two Genetic Mapping Approaches Reveal Distinct Sides of Disease Biology

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows.

6 Nov 2025

Ferroptosis Suppression Identified as a Key Driver of Lung Cancer Growth

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

6 Nov 2025

3D Ultrasound That Sees Entire Organ Blood Flow in Real Time

This study presents a multi-lens ultrasound system that offers tenfold higher resolution for whole-organ imaging, improving microvascular network visualization.

6 Nov 2025

Hidden Role of Biliverdin Reductase A in Fighting Oxidative Damage

According to a new study from Johns Hopkins Medicine, the enzyme biliverdin reductase A (BVRA) protects neurons directly from oxidative stress, regardless of whether it produces the yellow pigment bilirubin.

5 Nov 2025

RNA Molecules Alter Genome Structure to Silence Critical Neuronal Genes During Stress

What if the brain's response to stress could be read not in fleeting neurotransmitter bursts, but in the quieting of genes deep inside chromatin? Researchers at the University of Alabama at Birmingham have now shown that stress hormones may silence crucial neuronal genes through an unexpected class of RNA molecules that operate not by encoding proteins, but by reshaping the genome's architecture.

5 Nov 2025

Scientists Uncover How "P Bodies" Guide Stem Cells to Their Destinies

How do stem cells know what to become? Nearly three decades after scientists isolated the first human embryonic stem cells, researchers are still working hard to understand precisely how a single, undifferentiated cell can become any one of the roughly 200 cell types that make up the human body.

4 Nov 2025

Enzyme BVRA Found to Shield Neurons from Oxidative Stress

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.

4 Nov 2025

Weill Cornell Scientists Develop Safe and Precise Tool to Control Gene Activity

Investigators at Weill Cornell Medicine have developed a versatile and non-toxic technology for controlling the activity of any gene in a cell. Such "gene-switch" tools allow scientists to "turn on" or "turn off" a target gene to study how it works, model diseases and design new therapies.

4 Nov 2025