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UT Southwestern Researchers Develop Multi-Organ Gene Editing Strategy

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

23 Jun 2025

Fungal Spores in the Air May Predict Flu and COVID-19 Surges

Monitoring fungal spores in the outdoor air can predict surges in flu and COVID-19 infections, especially during the fall, according to a new study.

23 Jun 2025

New Technique Enhances Three Dimensional Immunolabeling in Thick Tissues

Three dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues.

20 Jun 2025

Do Genetic Variants That Affect DNA Methylation Influence Colorectal Cancer Risk or Outcomes?

The study identifies genetic variants influencing colorectal cancer risk through DNA methylation, suggesting new avenues for targeted screening and prevention.

20 Jun 2025

New Study Reveals Varied CAR T-Cell Therapy Benefits in Large B-Cell Lymphoma

A study identifies three patient subgroups in large B-cell lymphoma, revealing distinct responses to CD19 CAR T cell therapy and enhancing precision medicine.

20 Jun 2025

UQ Tech Bringing Regenerative Medicines Closer Than Ever

Tiny gel droplets enhanced with University of Queensland technology could open new pathways to repairing and replacing damaged organs.

20 Jun 2025

New STAMP Technique Combines Microscopy with Single-Cell RNA Analysis

Single-cell RNA sequencing provides scientists with important information about gene expression in health and disease.

18 Jun 2025

New Inherited Disorder Impairs DNA Repair and Raises Cancer Risk

A new hereditary condition has been discovered that affects patients' ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage caused by chemotherapy treatments.

18 Jun 2025

Researchers Develop Promising Vaccine for Vaginal Yeast Infections

The UGA vaccine offers a potential breakthrough in combating vaginal yeast infections, aiming to reduce reliance on antifungal drugs amid growing resistance.

18 Jun 2025

Bio-Rad Extends Anti-Idiotypic Antibody and SpyCatcher Reagent Ranges for Bioanalysis and Antibody Drug Development

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, today extended its range of recombinant monoclonal anti-idiotypic antibodies with the introduction of antibodies specific to pertuzumab (Perjeta), guselkumab (Tremfya), canakinumab (Ilaris), belimumab (Benlysta), and the bispecific drug emicizumab (Hemlibra).

18 Jun 2025

Study Finds Shared Brain Signature Across Autism Variants

New research from the University of Minnesota Medical School suggests that different genetic forms of autism may lead to similar patterns in brain activity and behavior. The findings were recently published in Nature Neuroscience.

16 Jun 2025

TUM Scientists Develop Breakthrough Method to Monitor CAR-T Cells

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets.

16 Jun 2025

Integrating Imaging and Molecular Profiling to Transform Treatment of Intrahepatic Cholangiocarcinoma

ICCA accounts for 10–15% of primary liver cancers and is notorious for late-stage diagnosis and resistance to chemotherapy and radiotherapy.

13 Jun 2025

Unlocking Drug Discovery with SOAR's Innovative Resource

Northwestern's SOAR database enhances drug discovery by mapping gene activity, aiding researchers in identifying treatment targets and understanding diseases.

13 Jun 2025

New Technique Revolutionizing Single-Cell Analysis with Lower Costs and Greater Scale

A new single-cell RNA analysis method, STAMP, significantly reduces costs and biases, allowing for comprehensive profiling of diverse cell populations.

13 Jun 2025

New Frontier in Understanding Brain Development and Rare Diseases

A groundbreaking study identifies unknown genetic disorders affecting brain development, offering new insights into neurodevelopmental conditions and diagnoses.

11 Jun 2025

Proteomic Signature in Blood Predicts Dementia and Diabetes Risk

A blood-based proteomic signature predicts healthspan, linking protein levels to disease risk and mortality, paving the way for targeted aging interventions.

10 Jun 2025

Spatial Transcriptomics Reshapes Musculoskeletal Research and Therapy

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

10 Jun 2025

Zebrafish Model Offers Hope for Treating Ultra-Rare Muscle Disease

Can a small fish help identify possible treatments for an ultra-rare inherited disease found in an Alabama boy? The genetic disease is XMEA, which progressively weakens the muscles and can affect the liver and heart.

6 Jun 2025

New Aging Clock Links Intrinsic Capacity to Immune Health and Longevity

A team of international researchers has developed a new biological age "clock" that estimates how well someone is aging, not just how "old" they or their various organs might be.

5 Jun 2025