therapeutics News and Research

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Novel Bio-Conjugation Method Achieves High Efficiency and Stability for Protein Modification

A group of researchers from the Pohang University of Science and Technology Department of Materials Science and Engineering, under the direction of Professor Seung Soo Oh and Dr. Hyesung Jo, have created a novel method that allows for the accurate modification of particular proteins in intricate biological settings.

27 Mar 2025

Zika and Dengue Virus Use Different Strategies to Infect Dendritic Cells

Zika virus and dengue virus are very close relatives. Both are mosquito-borne flaviviruses, and both specialize in infecting a host's dendritic cells.

26 Mar 2025

How Drug-Resistant Bacteria Use Antimicrobial Tools to Outcompete Others

A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominate strain.

24 Mar 2025

AGD Initiative Drives Progress in Drug Discovery with Sequencing of 250,000 Whole Genomes

Nashville Biosciences LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, and global DNA sequencing giant Illumina Inc. today announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative.

22 Mar 2025

Researchers Identify Promising Drug Candidates for Previously “undruggable” Cancer Target

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously “undruggable” cancer protein target, permanently blocking it.

21 Mar 2025

New Insights into RNA Editing Mechanisms for Autoimmune and Cancer Therapies

A research team led by Yang Gao from Rice University has made significant strides in understanding the molecular mechanisms of ADAR1, a protein that modulates ribonucleic acid (RNA) induced immune responses.

18 Mar 2025

Mitochondria Found to Control DNA Repair Protein and Delay Inflammaging

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way.

14 Mar 2025

Pig Retinal Organoids Offer Promising Model for Stem Cell-Based Vision Therapies

Inside the human eye, the retina is made up of several types of cells, including the light-sensing photoreceptors that initiate the cascade of events that lead to vision.

14 Mar 2025

Researchers Develop New Method for Assembling DNA Nanostructures

University at Albany researchers at the RNA Institute are pioneering new methods for designing and assembling DNA nanostructures, enhancing their potential for real-world applications in medicine, materials science and data storage.

13 Mar 2025

Circular RNA's Transformative Role in Tumor Biology and Treatment

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

10 Mar 2025

Investigating Ubiquitination's Role in Cancer Stem Cell Regulation

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

10 Mar 2025

$30 Million Grant Supports AI-Powered Antibody Therapy Development

An ambitious project led by Vanderbilt University Medical Center investigators aims to use artificial intelligence technologies to generate antibody therapies against any antigen target of interest.

10 Mar 2025

Dual Antibodies Found to Combat All SARS-CoV-2 Variants

A Stanford-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants. More research is needed, but the approach could help in the development of treatments to keep pace with evolving viruses.

6 Mar 2025

Minoryx Announces Dosing of the First Patient with Leriglitazone in the Phase 2a Study in Rett Syndrome (TREE Study)

Minoryx Therapeutics, a late-stage biotech company focused on the development of therapies for orphan central nervous system (CNS) disorders, today announces that the first patient in the TREE study has been dosed with leriglitazone.

6 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

Gut Microbes Transform Excreted Glucose into Crucial Fatty Acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

Study Unveils Phage-Bacteria Dynamics in the Early Life Gut Microbiome

A world of microbes resides within the gut of every human being. This vast microbial community, the microbiome, which includes bacteria and viruses, has repeatedly demonstrated its ability to actively contribute to both health and disease.

26 Feb 2025

Novel Catalysis Yields Elusive Fluorinated Oxetanes for Drug Discovery

Researchers at the National University of Singapore have developed a groundbreaking catalytic process that transforms epoxides into fluorinated oxetanes.

24 Feb 2025

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

22 Feb 2025

New 3D Lung Model Offers Personalized Aerosol Therapeutic Insights

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.

21 Feb 2025

therapeutics News and Research

Novel Bio-Conjugation Method Achieves High Efficiency and Stability for Protein Modification

Zika and Dengue Virus Use Different Strategies to Infect Dendritic Cells

How Drug-Resistant Bacteria Use Antimicrobial Tools to Outcompete Others

AGD Initiative Drives Progress in Drug Discovery with Sequencing of 250,000 Whole Genomes

Researchers Identify Promising Drug Candidates for Previously “undruggable” Cancer Target

New Insights into RNA Editing Mechanisms for Autoimmune and Cancer Therapies

Mitochondria Found to Control DNA Repair Protein and Delay Inflammaging

Pig Retinal Organoids Offer Promising Model for Stem Cell-Based Vision Therapies

Researchers Develop New Method for Assembling DNA Nanostructures

Circular RNA's Transformative Role in Tumor Biology and Treatment

Investigating Ubiquitination's Role in Cancer Stem Cell Regulation

$30 Million Grant Supports AI-Powered Antibody Therapy Development

Dual Antibodies Found to Combat All SARS-CoV-2 Variants

Minoryx Announces Dosing of the First Patient with Leriglitazone in the Phase 2a Study in Rett Syndrome (TREE Study)

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

Gut Microbes Transform Excreted Glucose into Crucial Fatty Acids

Study Unveils Phage-Bacteria Dynamics in the Early Life Gut Microbiome

Novel Catalysis Yields Elusive Fluorinated Oxetanes for Drug Discovery

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

New 3D Lung Model Offers Personalized Aerosol Therapeutic Insights

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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