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T cells are Sensitive to Genetic Disturbances Within Mitochondrial Power Plants

All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production.

7 Jul 2023

'Purecap' Technique Produces Highly Active mRNA Vaccines with Lower Immunostimulatory Activity

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

6 Jul 2023

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

The amount of data generated by scientists today is massive, thanks to the falling costs of sequencing technology and the increasing amount of available computing power.

22 Jun 2023

Neurotransmitter Receptor Patterns Define Key Organizational Principles in the Brain

Receptor patterns define key organizational principles in the brain, scientists have discovered.

20 Jun 2023

Reengineering the Cellular Synthetic Machinery to Produce Never-Before-Seen Polymers

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals -; from fuels to fabrics and drugs -; beyond the normal repertoire of microbes.

14 Jun 2023

Natural Peptide From Fruit Flies may Pave Way for New Antibiotics

Scientists at the University of Illinois Chicago have found that a peptide from fruit flies could lead to new antibiotics.

7 Jun 2023

Molecular Method Reveals Whether or Not Bacteria Respond to Antibiotics Within Minutes

Researchers at Karolinska Institutet have developed a molecular method able to detect whether or not bacteria respond to antibiotics within minutes.

23 May 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Researchers Examine the Role of TOR in LR Formation and its Interplay with Auxin Signaling

Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. An international team of plant biologists has demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to research team leader Prof. Dr Alexis Maizel of the Centre for Organismal Studies at Heidelberg University.

23 May 2023

Long-Ignored Antibiotic may Provide Much-Needed Protection Against Multi-Drug Resistant Bacteria

An old antibiotic may provide much-needed protection against multi-drug resistant bacterial infections, according to a new study publishing May 16th in the open access journal PLOS Biology by James Kirby of Harvard Medical School, US, and colleagues.

17 May 2023

Manipulating Brain Cells via Light Irradiation

An international research team, comprising scientists from DZNE, University Hospital Bonn, the Netherlands, and the US has been awarded a US$ 1.3 million grant by the "Human Frontier Science Program" to investigate brain immune cells and manipulate them via light irradiation.

8 May 2023

A Study on Gene Silencing Through a Recent Trial

Dr Catherine Mummery, a consultant neurologist at UCL Queen Square Institute of Neurology & the National Hospital for Neurology and Neurosurgery, has led a trial. The trial signifies for the first time that a “gene silencing” method has been taken in Alzheimer’s and dementia disease.

From University College London 27 Apr 2023

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Ribonucleic acids (RNAs) are single-stranded molecules that are found in all living organisms’ cells. As “transcripts” of human genes, mRNAs, for instance, play a role in the translation of genetic information by bearing the instructions for the production of a protein in their own sequence.

26 Apr 2023

Evolutionary Encounter of Two Protein Components Could Occur Entirely by Chance

Proteins are the key players for virtually all molecular processes within the cell. To fulfil their diverse functions, they have to interact with other proteins.

7 Apr 2023

SARS-CoV-2 infection hijacks and damages parts of infected cells' vital RNA machinery

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

30 Mar 2023

High-quality genome of a deep-sea eel illuminates the molecular mechanisms of deep-sea adaptation

Recently, the research team led by Dr. Shunping He from the Institute of Deep Sea Science and Engineering, Chinese Academy of Sciences, published their research findings in the online version of SCIENCE CHINA Life Sciences.

28 Mar 2023

Study identifies 238 amyloid toxicity protective or activator genes

An international study led by the Molecular Physiology Laboratory at the UPF Department of Medicine and Life Sciences (MELIS) identifies new genes that modulate the toxicity of the protein β-amyloid, responsible for causing Alzheimer's disease.

22 Mar 2023

The protein synthesis mechanism in the Giardia parasite

Cryo-electron microscopy was employed by Uppsala University researchers to reveal information on the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhea. The new findings could help in the development of specific medicines to combat Giardia and other protozoan parasites.

20 Mar 2023

Neoadjuvant dual immunotherapy and chemotherapy improve outcomes in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

20 Mar 2023

Translation News and Research

T cells are Sensitive to Genetic Disturbances Within Mitochondrial Power Plants

'Purecap' Technique Produces Highly Active mRNA Vaccines with Lower Immunostimulatory Activity

New Automated Machine Learning Tool to Design and Interpret Biological Sequences

Neurotransmitter Receptor Patterns Define Key Organizational Principles in the Brain

Reengineering the Cellular Synthetic Machinery to Produce Never-Before-Seen Polymers

Natural Peptide From Fruit Flies may Pave Way for New Antibiotics

Molecular Method Reveals Whether or Not Bacteria Respond to Antibiotics Within Minutes

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

Researchers Examine the Role of TOR in LR Formation and its Interplay with Auxin Signaling

Long-Ignored Antibiotic may Provide Much-Needed Protection Against Multi-Drug Resistant Bacteria

Manipulating Brain Cells via Light Irradiation

A Study on Gene Silencing Through a Recent Trial

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Previously Unknown Protein Reveals RNA Repair Mechanism in Humans

Evolutionary Encounter of Two Protein Components Could Occur Entirely by Chance

SARS-CoV-2 infection hijacks and damages parts of infected cells' vital RNA machinery

High-quality genome of a deep-sea eel illuminates the molecular mechanisms of deep-sea adaptation

Study identifies 238 amyloid toxicity protective or activator genes

The protein synthesis mechanism in the Giardia parasite

Neoadjuvant dual immunotherapy and chemotherapy improve outcomes in patients with resectable NSCLC

Analytical Chemistry - Industry Focus eBook eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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