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"Poisoned" form of a protein could set off events that encourage cancer growth

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

The University of Texas MD Anderson Cancer Center and Replay today announced the launch of Syena, a new oncology-focused product company pioneering T cell receptor (TCR) natural killer (NK) cell therapies.

15 Feb 2023

Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Notalgia paresthetica-;a nerve disorder characterized by a persistent itch in the upper back-;is a common and underdiagnosed condition worldwide.

9 Feb 2023

Gaining insights into human disease biology through CRISPR platforms

In this interview, we speak with Laralynne Przybyla about how she is utilizing CRISPR platforms to understand human disease biology in greater detail.

From Society for Laboratory Automation and Screening (SLAS) 7 Feb 2023

New insights into the lubrication mechanism of chocolate

Scientists found the physical process that takes place in the mouth when a piece of chocolate is eaten.

31 Jan 2023

Novel adoptive T cell receptor therapy shows promising results for patients with solid tumors

Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4), an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen, achieved clinically significant results for patients with multiple solid tumor types in a Phase I clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

30 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

New molecular profile of endometriosis to help improve therapeutic options

At Cedars-Sinai, a special and elaborate molecular profile of endometriosis has been engineered by investigators to help enhance therapeutic options for the millions of women suffering from the disease.

11 Jan 2023

Performing grafting and mobile CRISPR for genome editing in plants

An innovative twist to the CRISPR tool—also known as “genetic scissors”—is being utilized to edit plant genomes by researchers from the Max Planck Institute of Molecular Plant Physiology, signaling a methodology change.

4 Jan 2023

First-ever pedigree provides insights for maximizing genetic diversity in aquarium-bred corals

Corals bred in public aquaria provide novel research opportunities and a healthy stock for outplanting into the wild, essential components of a thriving future for coral reef ecosystems, which support around 25% of all life in Earth's oceans.

15 Nov 2022

Andor Launches New ZL41 Cell and Sona sCMOS Cameras

Andor Technology, an Oxford Instruments company and a world leader in scientific imaging solutions, has today announced the launch of two new scientific CMOS cameras, specifically designed for life science researchers.

From Andor Technology Ltd. 7 Nov 2022

Salivary miRNAs may be a promising biomarker for persistent post-concussive symptoms in children

Predicting clinical recovery of children with concussion is challenging. While concussion symptoms typically resolve within one to three weeks, up to one-third of children develop persistent post-concussive symptoms (PPCS), including headache, nausea, dizziness, blurred vision and sensitivity to light and/or sound.

26 Oct 2022

New consortium for scaled up meat produced from cultivated cells

Competition promotes innovation, but for a nascent industry, one strategy is for competitors to band together to tackle fundamental technical obstacles, set standards, and exchange knowledge in a way that benefits the industry as a whole.

20 Oct 2022

Building designer plant cuticles with important protective functions

Scientists are working to bioengineer a common defense mechanism that most plants develop naturally to protect against drought, insects and other environmental stresses.

11 Oct 2022

Chromosome restructuring suppresses meiotic recombination

The use of CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats) molecular scissors enables targeted editing, insertion, or suppression of genes in plants.

21 Sep 2022

The influence of mitochondria on evolution, food security, and climate change

The National Science Foundation (NSF) recently announced that it will support the work of a cooperative team of researchers, led by Elizabeth Vierling, Distinguished Professor of Biochemistry at the University of Massachusetts Amherst, who intend to spend the next four years researching the function of mitochondria in plant productivity.

13 Sep 2022

PhoreMost enters multi-project drug target discovery collaboration with Roche

PhoreMost to deploy its SITESEEKER platform to identify novel targets for Roche’s discovery programmes

From PhoreMost 6 Sep 2022

Re-defining the limits of single batch assay stabilisation

In response to increasing demand for stabilised molecular diagnostic assays, we have significantly increased our single batch lyophilised reagent bead manufacturing throughput to 300,000 reactions per freeze drying run and are now progressing towards a capacity of 100 million tests per annum.

From Biofortuna Limited 22 Aug 2022

Inventia Life Science and BioLamina partner to advance cell matrices for complex 3D cell models

As a result of this partnership, Inventia Life Science will now offer BioLamina’s extensive range of Biolaminin® products incorporated into the pre-validated library of RASTRUM™ Matrices, recapitulating the key motifs found in the native tissue of various cell types.

From Inventia Life Science 16 Aug 2022

Inventia Life Science Announces Partnership with PhenoVista Biosciences to Accelerate Preclinical Research with 3D Cell Models

Inventia Life Science, a leader in automated generation of complex 3D cell models, and PhenoVista Biosciences, a top provider of custom imaging-based phenotypic assay services, have entered into a partnership to deliver high-content cell-based assay services for drug discovery.