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Researchers establish and characterize a stable iPSC line for modeling human disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

RNA-G quadruplexes in living cells: A real-time study

Amyotrophic lateral sclerosis (ALS), sometimes referred to as Stephen Hawking’s disease and Lou Gehrig’s disease is a neurological condition that causes the body’s muscles to gradually lose control.

2 Feb 2023

Easy-to-use method quantifies exosomal miRNAs

Most cancer diagnostic procedures, like endoscopies, biopsies, and mammograms, are stressful and invasive. Although blood samples may be a less unpleasant option, only a few forms of the disease can as of now be diagnosed this way.

2 Feb 2023

Study uncovers a link between the genetic instructions for production and perception of sex pheromones

It's almost Valentine's Day, and love is in the air. Or in the waxy coating on your skin, if you are a vinegar fly. That's where flies encounter pheromones that play an important role in regulating sexual attraction.

1 Feb 2023

Exploring how plants can adapt to accelerating aridity due to climate change

At a time when climate change is making many areas of the planet hotter and drier, it's sobering to think that deserts are relatively new biomes that have grown considerably over the past 30 million years.

1 Feb 2023

Nearly two million-euro ERC Consolidator Grant supports research on fruit fly's locomotion

When we try walking in a straight line with our eyes closed, after a few steps forward we inevitably deviate from our intended path.

1 Feb 2023

Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

A genetic mutation in the SPTSSA gene is identified as the cause of Hereditary Spastic Paraplegia, a rare disease that causes progressive weakness, stiffness and spasticity in the lower extremities, according to a study, "SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia," published in Brain on on Jan. 30.

1 Feb 2023

UNC research describes another layer to the challenge of HIV latency

When people living with HIV take antiviral therapy (ART), their viral loads are driven so low that a standard blood test cannot detect the virus.

1 Feb 2023

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Research findings published in Frontiers in Immunology show that cancer immunotherapy does not interfere with COVID-19 immunity in previously vaccinated patients.

1 Feb 2023

Cochlear organoids provide a platform to understand sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

Analyzing how disease-causing fungi become resistant to antifungal drugs

An investigation has been performed by scientists as to how disease-causing fungi become resistant to antifungal drugs to help avoid possibly detrimental impacts of the growing resistance harmful microbes are developing to drugs.

31 Jan 2023

Tweezers illustrate how chemotherapy affects DNA

A recent study from Cornell University offers a new perspective on how the chemotherapy agent etoposide delays and kills vital enzymes that support the growth of cancer cells.

31 Jan 2023

Novel, more accurate computational tool for long-read RNA sequencing developed

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

31 Jan 2023

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

31 Jan 2023

Researchers discover new type of pathogenic fungus that infects potatoes

RUDN University biologists have discovered a new type of pathogenic fungus that infects potatoes and leads to massive crop loss.

31 Jan 2023

Proteins’ movement and the spread of antibiotic resistance

Umeå University researchers have figured out how a particular type of protein travels during DNA replication. The discovery could affect the current understanding of how bacteria propagate antibiotic resistance genes.

30 Jan 2023

Cryo-EM helps visualize the detailed structure of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

30 Jan 2023

Newly discovered genetic mutation may be a root cause of severe cases of childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

30 Jan 2023

Collaboration across European countries accelerates the characterization of an emergent plant virus

In the 21st century, "collaboration" has become a popular buzzword, but effectively working together across disciplines and countries is easier said than done.

27 Jan 2023

Deep-learning model for zinc finger design allows reprogramming of human transcription factors

Researchers at the University of Toronto and New York University have developed a novel technology that can engineer proteins to target any stretch of DNA in the human genome, opening a door toward gene therapies for a broader range of health conditions.

27 Jan 2023

Genetic News and Research

Researchers establish and characterize a stable iPSC line for modeling human disease

RNA-G quadruplexes in living cells: A real-time study

Easy-to-use method quantifies exosomal miRNAs

Study uncovers a link between the genetic instructions for production and perception of sex pheromones

Exploring how plants can adapt to accelerating aridity due to climate change

Nearly two million-euro ERC Consolidator Grant supports research on fruit fly's locomotion

Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

UNC research describes another layer to the challenge of HIV latency

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Cochlear organoids provide a platform to understand sensorineural hearing loss

Analyzing how disease-causing fungi become resistant to antifungal drugs

Tweezers illustrate how chemotherapy affects DNA

Novel, more accurate computational tool for long-read RNA sequencing developed

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

Researchers discover new type of pathogenic fungus that infects potatoes

Proteins’ movement and the spread of antibiotic resistance

Cryo-EM helps visualize the detailed structure of viral genome replication machinery

Newly discovered genetic mutation may be a root cause of severe cases of childhood glaucoma

Collaboration across European countries accelerates the characterization of an emergent plant virus

Deep-learning model for zinc finger design allows reprogramming of human transcription factors

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