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Scientists reveal the origins and provide a detailed ID card of pancreatic endocrine stem cells

The pancreas is a key metabolic regulator. When pancreatic beta cells cease producing enough insulin, blood sugar levels rise dangerously — a phenomenon known as hyperglycemia — thus triggering diabetes.

20 Apr 2022

A new rule book for the design of therapeutic cells with improved specificity and safety

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

18 Apr 2022

Researchers explore a new procedure to disrupt gene regulation

What role does DNA packing play in regulating gene activity? Fanka Rang and Kim de Luca, researchers from Jop Kind’s (group leader at the Hubrecht Institute and Oncode Investigator) group, created a way to monitor both gene activity and DNA packaging at the same time to address this topic.

5 Apr 2022

Lifebit; Making Biomedical Data Accessible

In this interview, we speak to Dr. Maria Chatzou Dunford, CEO of Lifebit, about their technology and how it helps scientists to make better use of their data.

From Lifebit 1 Apr 2022

Novel protein Atossa regulates cell invasion

Researchers from the Institute of Science and Technology Austria have found a novel protein that stimulates energy generation inside immune cells, allowing them to penetrate more effectively.

24 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

Intestinal cell changes are driven by the BMP signaling pathway, study finds

Intestinal cells can change specializations during their lives. The BMP signaling pathway – an important communication mechanism between cells – appears to be the driver of these changes.

2 Mar 2022

Looking at protein activity gives a complete picture of leukemia's weaknesses

Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows.

28 Feb 2022

New technique uses microscopic magnetic particles to remotely activate brain cells

Scientists at UCL have developed a new technique that uses microscopic magnetic particles to remotely activate brain cells; researchers say the discovery in rats could potentially lead to the development of a new class of non-invasive therapies for neurological disorders.

From University College London 24 Feb 2022

Dotmatics releases Platform 22.1

Latest Platform delivers new capabilities to streamline lab workflows and support customers’ data-informed decision making.

From Dotmatics 23 Feb 2022

New and unconventional nuclear function for oncogenic microRNA discovered

microRNAs (miRNA), non-coding RNA molecules, are widely known for regulating mRNA stability and translation. miR-10b has been increasingly implicated in the pathogenesis of gliomas, cancers of the brain.

16 Feb 2022

Cryobioprinting; A New Bioprinting Technique

In this interview, we speak to Dr. Y. Shrike Zhang about his latest bioprinting technique that allows tissues to be preserved for later use.

From Harvard Medical School 4 Feb 2022

Human rRNA genes differed based on a person’s geographic ancestry

Genome research that explored gene variants that are considered a crucial building block for protein-synthesizing microscopic structures took an unexpected turn.

4 Feb 2022

Using AI solutions to predict cell fates

Data is not only the answer to numerous questions in the business world; the same applies to biomedical research. In order to develop new therapies or prevention strategies for diseases, scientists need more and better data, faster and faster.

3 Feb 2022

Researchers aim to tackle neurodegenerative diseases of the eye and brain

Could a new paradigm in digital health treat blinding disorders and possibly also be a conduit for treating other parts of the brain? A multi-disciplinary team of world-renowned researchers at USC are exploring this exciting possibility.

31 Jan 2022

RNA sequencing picks up more genetic changes in pediatric cancer patients than traditional tests

Analysis of the entire tumor RNA picks up more clinically relevant genetic changes in children with cancer than traditional diagnostic methods, new research has shown.

28 Jan 2022

An Interview with The Million Veteran Program (MVP)

In this interview, we speak to Dr. Sumitra Muralidhar, the Program Director for VA’s Million Veteran Program (MVP) about the program and its aims for veterans.

28 Jan 2022

Leukemia-on-a-chip; The Future of Preventing Therapy Resistance?

We speak to Dr. Chao Ma, one of the speakers at SLAS 2022, about his groundbreaking 'leukemia-on-a-chip' technology and its future within therapy resistance.

From Society for Laboratory Automation and Screening (SLAS) 27 Jan 2022

Study findings greatly expand the ability to engineer long-range genome edits

Researchers discovered the potential of CRISPR, a tool used by bacteria to defend themselves against viral intruders, nearly a decade ago.

24 Jan 2022

Researchers develop a three-dimensional, fully dynamic kinetic model of a living minimal cell

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

21 Jan 2022