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Nutrient Tug-of-War Between Tumor and Immune Cells Could Be Targeted for Cancer Therapy

Scientists at St. Jude Children's Research Hospital found immune and tumor cells compete over glutamine, a major nutrient in their local environment, with significant implications for anti-cancer activity.

6 Jul 2023

Novel Peptide may be Key to Understanding Skin Aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "A novel peptide 'T14' reflects age and photo-aging in human skin."

6 Jul 2023

Researchers Develop New Way to Genetically Suppress Malaria-Carrying Mosquitoes

Malaria remains one of the world's deadliest diseases. Each year malaria infections result in hundreds of thousands of deaths, with the majority of fatalities occurring in children under five.

6 Jul 2023

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

6 Jul 2023

Triazoles: A Threat to Wild Birds

According to new research, wild birds living in vineyards are more vulnerable to triazole fungicide contamination than other agricultural landscapes.

5 Jul 2023

Uncovering the Role of Cochlear Signal in Hearing Loss

A cochlear signal, the precise role of which has been uncertain since its discovery around 70 years ago, probably gives the brain information on whether the ear is working normally or not.

5 Jul 2023

Next Step in Sartorius Partnership Finalized: Several Subsales and Distribution Agreements as Well as R&D Project Agreements Have Been Signed

During May and June 2023 several sub-sales and distribution agreements were signed between Sartorius and BICO companies CELLINK, Advanced BioMatrix (ABM) and Dispendix.

From BICO 5 Jul 2023

Understanding How Malaria Parasite Modulates Apicoplast Gene Expression

A recent study supported by Tokyo Tech’s World Research Hub Initiative discovered that gene expression within the apicoplast, an organelle in the malaria parasite Plasmodium falciparum, is controlled by melatonin (the circadian signaling hormone) in host blood and intrinsic parasite cues via a factor called ApSigma.

5 Jul 2023

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

According to new research published in Nature Biotechnology, artificial intelligence can predict on- and off-target behavior of CRISPR tools that target RNA rather than DNA.

5 Jul 2023

Genetically Modified iPS Cell Applications for Fabry Disease

iPS cells have had a significant impact on biology and medicine, and they are expected to increase regenerative medicine. Clinical trials with various cell types derived from iPS cells have been performed since 2014 when a sheet of retinal pigment epithelial cells obtained from iPS cells was transplanted into patients with age-related macular degeneration.

4 Jul 2023

Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

The tumor suppressor protein p53 has been nicknamed the “guardian of the genome” because it safeguards the DNA from long-term damage or stress by controlling the expression of numerous genes involved in DNA repair, cell division, and cell death.

3 Jul 2023

Tiny Sea Creature Offers Insights into Healing and Aging

National Institutes of Health researchers and their collaborators revealed fresh insights into healing and aging by studying how a small marine creature regenerates a completely new body from only its mouth.

3 Jul 2023

Ancient Virus-Like Transposons Found to Mediate Horizontal Gene Transfer in Worms

Scientists have known for decades that genes can be transferred from one species to another, both in animals and plants.

30 Jun 2023

The First Programmable RNA-Guided System in Eukaryotes Uncovered

Feng Zhang of the Broad Institute at MIT and Harvard and the McGovern Institute for Brain Research at MIT headed a team of researchers who discovered the first programmable RNA-guided mechanism in eukaryotes, which include fungi, plants, and animals.

29 Jun 2023

Mechanisms of MCL-1 Inhibitor-Induced MCL-1 Protein Upregulation and Induction of Apoptosis

A new editorial paper was published in Oncotarget's Volume 14 on June 21, 2023, entitled, "Decoding the mechanism behind MCL-1 inhibitors: A pathway to understanding MCL-1 protein stability."

29 Jun 2023

Study Examines Neural Activity and Wake-Like Skin Patterning of Octopus During Their Sleep

When octopuses sleep, their quiet periods of slumber are punctuated by short bursts of frenzied activity. Their arms and eyes twitch, their breathing rate quickens, and their skin flashes with vibrant colors.

29 Jun 2023

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine and Baylor College of Medicine has created the world's largest and most comprehensive map of normal breast tissue, providing an unprecedented understanding of mammary biology that may help identify therapeutic targets for diseases such as breast cancer.

29 Jun 2023

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor prognosis in its advanced stages.

29 Jun 2023

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Johns Hopkins Medicine scientists say they have developed a nanoparticle -; an extremely tiny biodegradable container -; that has the potential to improve the delivery of messenger ribonucleic acid (mRNA)-based vaccines for infectious diseases such as COVID-19, and vaccines for treating non-infectious diseases including cancer.

29 Jun 2023

Disclosing the Key Role of Mitofusin 2 Cellular Makeup in Interconnecting Organelles Within Cells

Researchers at IRB Barcelona, the University of Barcelona (UB), VIMM, and the University of Padua unveil the key role of Mitofusin 2 cellular makeup in interconnecting organelles within cells.

29 Jun 2023

Cell News and Research

Nutrient Tug-of-War Between Tumor and Immune Cells Could Be Targeted for Cancer Therapy

Novel Peptide may be Key to Understanding Skin Aging

Researchers Develop New Way to Genetically Suppress Malaria-Carrying Mosquitoes

Glutaminase 2 Plays a Key Role in Glucose Homeostasis

Triazoles: A Threat to Wild Birds

Uncovering the Role of Cochlear Signal in Hearing Loss

Next Step in Sartorius Partnership Finalized: Several Subsales and Distribution Agreements as Well as R&D Project Agreements Have Been Signed

Understanding How Malaria Parasite Modulates Apicoplast Gene Expression

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

Genetically Modified iPS Cell Applications for Fabry Disease

Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

Tiny Sea Creature Offers Insights into Healing and Aging

Ancient Virus-Like Transposons Found to Mediate Horizontal Gene Transfer in Worms

The First Programmable RNA-Guided System in Eukaryotes Uncovered

Mechanisms of MCL-1 Inhibitor-Induced MCL-1 Protein Upregulation and Induction of Apoptosis

Study Examines Neural Activity and Wake-Like Skin Patterning of Octopus During Their Sleep

Understanding Mammary Biology That May Help Find Therapeutic Targets for Breast Cancer

Analyzing the Role of Pyroptosis in Improving the Treatment of Lung Cancer

New Nanoparticle Developed Helps Improve the Delivery of mRNA-Based Vaccines

Disclosing the Key Role of Mitofusin 2 Cellular Makeup in Interconnecting Organelles Within Cells

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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