Antibodies News and Research

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New Insights Into Antibody Glycans may Advance Tuberculosis Prevention

Certain antibodies inhibit Mycobacterium tuberculosis, the cause of tuberculosis (TB), the infectious disease that claims the most lives worldwide, a study led by UT Southwestern Medical Center researchers found.

23 Feb 2026

New Antibodies Prevent EBV Infection in Humanized Mouse Models

Fred Hutch Cancer Center scientists reached a crucial milestone in blocking Epstein Barr virus (EBV), a pathogen estimated to infect 95% of the global population that is linked to multiple types of cancer, neurodegenerative diseases and other chronic health conditions.

18 Feb 2026

Artificial Intelligence Enables Stable Intrabody Design in Cells

A new artificial intelligence-driven pipeline developed in a collaborative research combines protein structure prediction, sequence design, and live-cell screening together to enable rapid conversion of antibody sequences into functional intracellular antibodies (intrabodies) that are stable within living cells.

16 Feb 2026

Machine Learning Model Accelerates Manufacturing Timeline of Monoclonal Antibodies

As instigators of immunity, monoclonal antibodies are marvels of modern medicine, lab-made proteins that can treat cancers, autoimmune diseases, and many other conditions.

10 Feb 2026

DNA Origami Vaccine Scaffolds Sharpen Immune Targeting Against HIV

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus.

6 Feb 2026

Sugar Molecules Point to a New Weapon Against Drug-Resistant Bacteria

Australian researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognize a sugar found only on bacterial cells – an advance that could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections.

4 Feb 2026

Gravity-Driven Microfluidic Platform Enhances Immune Cell-Tissue Co-Culture

Advanced in vitro models such as organ-on-chip systems aim to replicate human physiology more accurately than conventional cell cultures. However, most existing platforms struggle to incorporate circulating cells like immune cells or circulating tumor cells.

3 Feb 2026

Lower IgG Hinge Controls Antibody Assembly and Immune Function

The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control hub, according to a study by researchers at Science Tokyo.

31 Jan 2026

AI-Designed CytoTape Records Cellular Events Over Time With High Resolution

Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and across large cell populations.

27 Jan 2026

Prospera™ Featured in Landmark Interventional Study Advancing Lung Transplant Care

Natera, Inc., a global leader in cell-free DNA and precision medicine, today announced the publication of a new prospective clinical trial in Transplantation Direct. The study, which was conducted by The Ohio State University Wexner Medical Center (OSU-WMC), was initiated to explore whether donor-derived cell-free DNA (dd-cfDNA) surveillance, and specifically Prospera-guided monitoring, could reduce the number of invasive biopsies for patients following lung transplantation.

From Natera 27 Jan 2026

Rigid Protein Molecular Rulers Enable Precise Control of Antibody Conformation

By extending a naturally rigid bacterial protein by 50% while preserving geometry and stability, the study introduces protein-based "molecular rulers" that could probe antibody shape, limit unwanted motion, and support safer, more effective antibody drug design.

21 Jan 2026

Unveiling How a Respiratory Bacterium Obtains Lipids and Targets Fatty Tissues

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

16 Jan 2026

A Week of 40-Hz Sound Triggers Long-Lasting Amyloid Changes in Monkeys

Forty-hertz auditory stimulation in aged monkeys doubles CSF amyloid-β levels, offering insights into non-invasive strategies for Alzheimer's disease treatment.

15 Jan 2026

Rare EBV-Driven B Cell Event May Spark Multiple Sclerosis Onset

Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

14 Jan 2026

Unusual Antibody Tactics Hinder Pathogen Attachment to Cells

Pathogens can create sticky situations. When microbes invade the body to cause an infection, often one of their first lines of attack is to cling tenaciously to the surfaces of targeted human cells.

8 Jan 2026

Genetic Differences Can Undermine Antibody-Based Therapies

The genome differs from person to person in thousands of positions. In some cases, this means that proteins have a different building block in certain regions, rendering some antibody-based therapies ineffective, report researchers from the University of Basel, Switzerland.

18 Dec 2025

Light-Based Technique Reveals How Extracellular Vesicles Interact With Cells

The tiny bubbles that carry signals between cells throughout the body were discovered decades ago, but precisely what they contain and how their cargo affects recipient cells is still largely a mystery.

12 Dec 2025

Visualizing How Cancer Seed Cells Evade Brain Immunity

Metastasis occurs when cancer cells break away from the original tumor and travel through the bloodstream to form new tumors in other parts of the body. It is the leading cause of cancer-related death. Brain metastasis is particularly severe and affects 10-30% of patients with advanced lung, breast, and melanoma cancers.

12 Dec 2025

PLAMseq Revolutionizes Simultaneous Analysis of Genome Proteins and Their Locations

A team from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) has developed an innovative technique called PLAMseq (proximity-labelled affinity-purified mass spectrometry plus sequencing) that, for the first time, allows simultaneous analysis of chromatin-associated proteins and their location in the genome in a single experiment.

5 Dec 2025

Engineered Gut Bacteria With MiRNA Nanoparticles To Reverse IBD

Biomimetic nanoparticles delivering microRNA to gut bacteria enhance protective metabolites, repair intestinal barriers, and alleviate colitis symptoms.

3 Dec 2025