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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Breakthrough Platform Could Accelerate Therapeutic Development for Mitochondrial Disorders

Some of your most important life partners are the mitochondria that power all your cells. You and these little cellular powerhouses are in a 1.5-billion-year-old evolutionary relationship-but mitochondria brought some baggage.

7 Apr 2026

Researchers Discover Prenatal Genetic Origins of Childhood Absence Epilepsy

Researchers at Baylor College of Medicine have uncovered a previously unrecognized mechanism by which inherited calcium channel mutations disrupt early brain development and predispose children to epilepsy and related cognitive challenges.

6 Apr 2026

Neural Circuit Controls Aggression Intensity in Stressed Mice

For many animals, aggression is essential for territorial defense. However, excessive aggression increases the risk of serious injury.

3 Apr 2026

Defining Tumor Microbiota for Improved Cancer Diagnosis and Treatment

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

3 Apr 2026

A Single-Celled Organism Uses Geometry To Sense Its World

Stentor coeruleus, a single-celled organism approximately one millimeter long, has a unique ability, according to a startling discovery made in the lab.

3 Apr 2026

A Python-Inspired Molecule Suppresses Appetite After Eating

The study identifies pTOS as a key metabolite in appetite suppression, highlighting a gut–liver–brain pathway with implications for obesity therapy.

2 Apr 2026

Excessive RNA Editing May Explain Neurological Differences in Down Syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome. The study was a collaboration among scientists from the Icahn School of Medicine at Mount Sinai, the Lieber Institute for Brain Development, the Medical University of Sofia in Bulgaria, and the University of Arizona.

2 Apr 2026

Mirror Protein Design Blocks Amyloid Beta in Alzheimer’s Disease

Understanding how proteins interact with their own mirror images enabled a Kobe University research team to design a small mirror protein that disables a causal factor of Alzheimer's disease, amyloid-beta.

1 Apr 2026

Zebrafish Use Integrated Visual Signals to Move Up and Down in the Ocean

Using zebrafish, researchers from Osaka Metropolitan University (OMU) have identified the tegmentum region in the fish midbrain as the area where light input from both the fish's eyes and the pineal organ-the 'third eye'-is integrated.

31 Mar 2026

Study Reveals How Distributed Networks Support Complex Behavior

Understanding how the brain works requires more than studying single regions in isolation. The cerebral cortex depends on long-distance connections that link specialized areas into coordinated networks. But scientists have had limited tools for selectively turning these specific connections "on" or "off" in animal models that most closely resemble the human brain.

31 Mar 2026

Novel Immunotherapy Disrupts the Protective Tumor Microenvironment Ecosystem

Chimeric antigen receptor T-cell therapy - CAR T for short - has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two main reasons: tumor cells often don't share one consistent surface target, and many solid tumors are protected by a dense network of scar tissue and immune-suppressive cells that blocks T cells.

31 Mar 2026

Identifying the Cellular Origin of MS-Related Neuroinflammation

Signals from the gut have been linked to autoimmune inflammation, but fundamental cellular processes remain poorly understood.

30 Mar 2026

New Neural Organoid System Enables Scalable Brain Network Studies

Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields.

30 Mar 2026

Fusion Protein Rewires Brain Development to Trigger Pediatric Cancer

A team of researchers at Baylor College of Medicine, St. Jude Children's Research Hospital, Texas Children's Hospital and collaborating institutions reveal in the journal Nature a novel mechanism that drives the development of pediatric supratentorial ependymoma (EPN), the third most common pediatric brain tumor.

28 Mar 2026

Researchers Identify the Nuclear Root of Cellular Aging

Some aging indications in human cells arise in the cell nucleus, where the packaged form of DNA changes with age.

27 Mar 2026

The Future of Vision Restoration With ReVision Implant

ReVision Implant is pioneering neuroprosthetic technology to restore vision in blind patients using advanced cortical implants and flexible electrode arrays.

26 Mar 2026

SLIT3 Protein Drives Brown Fat Activation Through Dual Signaling

Researchers have determined how a key protein activates brown fat by expanding blood vessels and nerves in the heat-generating tissue.

26 Mar 2026

Reversing Memory Loss in Aging Mice by Targeting Gut Bacteria

The study uncovers how gut bacteria like Parabacteroides goldsteinii contribute to memory decline, offering insights for potential cognitive interventions.

26 Mar 2026

New PanNDA Atlas Maps Protein Networks in Neurodegenerative Diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

24 Mar 2026