Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Gravity-Driven Microfluidic Platform Enhances Immune Cell-Tissue Co-Culture

Advanced in vitro models such as organ-on-chip systems aim to replicate human physiology more accurately than conventional cell cultures. However, most existing platforms struggle to incorporate circulating cells like immune cells or circulating tumor cells.

3 Feb 2026

Brain's Aging Waste System Linked to Synapse Loss and Cognitive Decline

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why.

3 Feb 2026

Study Uncovers a Crucial Factor to Improve Treatment for Glioblastoma

A groundbreaking study from Brown University Health researchers has identified a crucial factor that may help improve treatment for glioblastoma, one of the most aggressive and common forms of adult brain cancer.

2 Feb 2026

Bacteria's Hidden Communication Network Drives Drug Resistance

Biologists have uncovered a new mode of communication inside cells that helps bacterial pathogens learn how to evade drugs.

2 Feb 2026

Human Neurons Reveal Why Some Cells Resist Tau Protein Buildup

New research by UCLA Health and UC San Francisco has uncovered why certain brain cells are more resilient than others to the buildup of a toxic protein that is a hallmark of Alzheimer's disease and related dementias, potentially leading to new targets for therapies or treatments.

31 Jan 2026

AI Decodes Evolutionary Programs Shaping the Mammalian Cerebellum

Artificial intelligence allows tracing the evolution of genetic control elements in the developing mammalian cerebellum.

31 Jan 2026

Fruit Fly Neurons Explain When Food Feels Rewarding

Why do we sometimes keep eating even when we're full and other times turn down food completely? Why do we crave salty things at certain times, and sweets at other times?

31 Jan 2026

Visualizing Real-Time DNA Transcription in a Living Mouse

DNA can be regarded as an extensive library that contains all genetic information. Cells do not utilize this information simultaneously.

30 Jan 2026

Autism-Linked Mutations Converge on Shared Early Brain Pathways

UCLA Health researchers have created a comprehensive map showing how eight different genetic mutations associated with autism spectrum disorder affect early brain development, providing new insights into the ways diverse genetic causes may lead to shared features and symptoms of the disorder.

29 Jan 2026

Cellular Garbage Collector Shields Neurons From Alzheimer’s Damage

Researchers at UC San Francisco have identified a hazardous waste collector in the brain that disposes of the toxic clumps of tau protein that can lead to dementia.

29 Jan 2026

Natural Molecular Brake Prevents Uncontrolled DNA Replication in Cells

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we would die.

29 Jan 2026

Understanding the Complex Biosynthetic Pathway of O-Mannose Glycans in the Brain

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the formation of complex glycans essential for normal brain function.

28 Jan 2026

Advanced 3D Tumor Organoids Reveal How Glioblastoma Responds to Immunotherapy

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors in a setting that closely mirrors the human brain, shedding light on how the aggressive cancer interacts with surrounding brain cells and the immune system to become more invasive and resistant to therapy.

28 Jan 2026

AI-Designed CytoTape Records Cellular Events Over Time With High Resolution

Unraveling the mysteries of how biological organisms function begins with understanding the molecular interactions within and across large cell populations.

27 Jan 2026

Large African Ancestry Genetic Study Reveals Shared Biology Of Schizophrenia

A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.

24 Jan 2026

Maternal And Fetal Cell Exchange Shapes Health Across Multiple Generations

During pregnancy, maternal and fetal cells migrate back and forth across the placenta, with fetal cells entering the mother's bloodstream and tissues.

24 Jan 2026

Protein Translation Enzyme Governs Macrophage Maturation and Tissue Homeostasis

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an enzyme involved in protein translation is essential for circulating immune cells, called monocytes, to mature into tissue-resident macrophages, a specialized population of immune cells that maintain organ health by clearing dead cells and debris.

24 Jan 2026