Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Centriolar Satellites Coordinate Crucial Internal Cellular Protein Trafficking Networks

Inside every cell, thousands of proteins must reach the right place at the right time. Helping coordinate this complex logistics network are centriolar satellites-tiny, membrane-less organelles that play important roles in protein trafficking, cell division, and the formation of cilia.

22 Aug 2026

Mapping Diverse Brain Cell Populations Unlocks Deep Hidden Molecular Secrets

Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue.

22 Aug 2026

New MOSAIC Microscope Captures Biological Processes Across Multiple Scales

Biology doesn’t happen at one scale. Molecular interactions unfold in milliseconds and nanometers, while disease-associated change such as in Alzheimer’s spreads across millimeters of brain tissue.

21 Aug 2026

Scientists Give Lab-Grown Brain Organoids a Regional Biological Compass

The human brain is often described as one of the most complex structures in biology, and much of its power comes from how it's organized.

21 Aug 2026

Multiple Specialized Immune Cells Cooperate to Suppress Opportunistic Lung Fungi

Most people carry the fungus Cryptococcus neoformans in their lungs for life and never know it, held in check by the immune system.

21 Aug 2026

Reengineering Glial Cell Signaling Pathways to Slow Down ALS Symptoms

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that, according to the CDC, currently impacts around 35,000 Americans-with 5,000 more diagnosed each year.

21 Aug 2026

Locally Activated Skull T Cells Halt Glioblastoma Growth in Mice

Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as rapid first responders against brain cancer before distant lymph nodes get the signal that abnormal cells are present.

20 Aug 2026

Study Uncovers Cellular Accumulators Tracking Brain Electronic Sleep Pressure

Why does staying awake inevitably make us sleepy? Researchers at the University of Basel, Switzerland, have identified neuronal populations in the brain of mice that become activated during prolonged wakefulness and are crucial for sleep drive.

20 Aug 2026

Innovative LATeNT Platform Controls Neural Paths to Treat Brain Disorders

DGIST (President Kunwoo Lee) announced that a research team led by Professor Ji Won Um of the Center for Synapse Diversity and Specificity, Department of Brain Sciences, in collaboration with a research team led by Professor Alice Ting at Stanford University, has developed LATeNT, a novel optical control platform that uses light to block signal transmission between neurons and subsequently restore normal signaling.

19 Aug 2026

New Potential Target for Triple-Negative Breast Cancer

The study uncovers how macrophages recruit nerves in triple-negative breast cancer, suggesting BDNF signaling as a critical factor in tumor progression.

18 Aug 2026

Modular Brain Structures Reuse Neural Networks to Simplify Complex Actions

As we move through everyday life, our brains engage in a huge variety of cognitive tasks. For example, during a grocery run, we might have to recall the items for a recipe, remember where the clerk said the flour was located, and count out money to pay.

18 Aug 2026

Breakthrough Discovery Pinpoints How Brain Immune Cells Respond to Toxic Cellular Waste

Researchers at the University of California, San Diego, and their colleagues have discovered a critical cellular mechanism that causes brain degeneration in both a rare childhood condition and the far more prevalent Alzheimer’s disease.

17 Aug 2026

High-Speed Microscope Captures Millisecond-Scale Brain Signaling Activity

Within the brain, neurons compute by generating electrical impulses. These signals travel throughout neurons, which are in turn connected in vast networks that control brain functions such as sensory perception, memory formation, and control of movement.

17 Aug 2026

New Study Links TIMP2 Loss to Microglial Immune Dysfunction

Researchers at The Icahn School of Medicine at Mount Sinai have identified a role for the youth-associated protein TIMP2 in supporting the healthy function of microglia, the brain's resident immune cells.

17 Aug 2026

New Mouse Study Challenges Traditional Theories of Long-Term Memory Storage

Memories can survive even after the brain temporarily loses more than half of its synaptic connections, according to a new mouse study, which challenges the long-held view that long-term memories depend on stable individual synapses.

14 Aug 2026

Study Reveals Why People Are At Greater Risk of Fungal Infections Than Others

A study on Candida albicans uncovers immune mechanisms that prevent systemic infections, emphasizing the role of IL-1 cytokines and neutrophil response.

13 Aug 2026

New Roadmap Fixes Cellular Waste Accumulation to Halt Brain Degeneration

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

13 Aug 2026

Neural Stem Cell Protein CCN1 Guides Microglial Distribution During Development

The development of the central nervous system (CNS) depends on the coordinated interactions between neural stem cells (NSCs) and resident immune cells to regulate neurogenesis, tissue organization, and brain maturation.

12 Aug 2026

New Study Reveals How Genetic Mutations Hijack the Parkinson's LRRK2 Switch

Researchers at Weill Cornell Medicine have uncovered how a key Parkinson's protein called LRRK2 shifts between inactive and active forms, revealing the structural changes that enable certain mutations to push the protein into an overactive state.

11 Aug 2026

McMaster Team Identifies Natural Immune Defense Against Advanced Fatty Liver Disease

Researchers at McMaster University have discovered that a naturally occurring hormone best known for suppressing appetite and promoting weight loss also helps protect the liver from inflammation through a previously unknown signaling pathway, opening new possibilities for treating advanced fatty liver disease.

11 Aug 2026