Cardiometabolic News and Research

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New Polygenic Risk Scores Transform Disease Prediction for Han Chinese Populations

Researchers at Academia Sinica have developed the first population-specific polygenic risk score (PRS) models for people of Han Chinese ancestry, achieving unprecedented accuracy in predicting risks for common diseases such as diabetes, heart disease, autoimmune disorders.

22 Nov 2025

Genetic Variants Reveal Unexpected Link Between Obesity Risk and Cholesterol Levels

Individuals with a genetic profile that puts them at risk of obesity may not necessarily be at risk of having high cholesterol, UTHealth Houston researchers discovered.

31 Oct 2025

Single-Cell Map Reveals Epigenomic Regulation of Human Fat Tissue

A new study has created the first single-cell map of how DNA is regulated and organized inside different cell-types of human fat tissue.

21 Aug 2025

New Computational Tool Enhances Gene Discovery in Heart and Metabolic Diseases

Genetic changes can signal evidence of disease, but pinpointing which genes and what's changed can be difficult.

16 Jul 2025

Meta-Analysis Identifies Genome-Level Associations of FOXP4 Gene With Long COVID

New genome-wide meta-analysis shows FOXP4 gene variants elevate the risk of long COVID (PASC), linking genetic predisposition to persistent symptoms and lung dysfunction. Findings support tailored treatment approaches.

30 May 2025

Variance Analysis Enhances Genetic Risk Prediction for Blood Cell Traits

A Nature Communications study shows that incorporating variance polygenic scores (vPGS) and variance QTLs (vQTLs) improves genetic risk prediction for blood-related diseases, offering new insight into phenotype variability and lifestyle factors like alcohol intake.

15 May 2025

Study Shows the Impact of Exposome on Serum Metabolites in Children

The combined effect of environmental exposures and unhealthy lifestyle habits can affect children's cardiometabolic health in a way that exceeds their separate effects.

24 Jul 2024

Exploring Gut Microbiome Modulation for Disease Prevention

Carriers of gut Blastocystis, a single-celled organism that has been classified as either a parasite or harmless organism but is frequently found in the digestive system, were associated with markers of good cardiovascular health and decreased body fat in an analysis of over 50,000 people from around the world.

9 Jul 2024

Researchers Develop New Way to Simulate Personalized, Microbiome-Mediated Diet Responses

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer risk, and more.

25 Jun 2024

Maintaining Regular Sleep Patterns May Improve Gut Health

New research has found irregular sleep patterns are associated with harmful bacteria in your gut.

3 Aug 2023

New signals of natural selection in humans identified

A team of global experts has discovered new signals of natural selection in humans.

2 Mar 2023

Non-nutritive sweeteners do not increase blood glucose and other endocrine responses, study shows

New research conducted by a team of scientists at the University of Toronto has shown that non-nutritive sweeteners (NNS) do not increase blood glucose and other endocrine responses.

22 Feb 2023

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

17 Jan 2022

Changes in the activity of gene networks may explain arteriosclerosis risk

Up to 60 percent of the risk associated with coronary arteriosclerosis may be explained by changes in the activity of hundreds of genes working together in networks across several organs in the body.

13 Jan 2022

Commonly used drugs have powerful effects on the gut microbiome, research shows

We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute the highest cause of mortality worldwide.

9 Dec 2021

Cardiometabolic News and Research

New Polygenic Risk Scores Transform Disease Prediction for Han Chinese Populations

Genetic Variants Reveal Unexpected Link Between Obesity Risk and Cholesterol Levels

Single-Cell Map Reveals Epigenomic Regulation of Human Fat Tissue

New Computational Tool Enhances Gene Discovery in Heart and Metabolic Diseases

Meta-Analysis Identifies Genome-Level Associations of FOXP4 Gene With Long COVID

Variance Analysis Enhances Genetic Risk Prediction for Blood Cell Traits

Study Shows the Impact of Exposome on Serum Metabolites in Children

Exploring Gut Microbiome Modulation for Disease Prevention

Researchers Develop New Way to Simulate Personalized, Microbiome-Mediated Diet Responses

Maintaining Regular Sleep Patterns May Improve Gut Health

New signals of natural selection in humans identified

Non-nutritive sweeteners do not increase blood glucose and other endocrine responses, study shows

Risk linked to coronary arteriosclerosis may be explained by changes in gene networks

Changes in the activity of gene networks may explain arteriosclerosis risk

Commonly used drugs have powerful effects on the gut microbiome, research shows

Long-term exposure to particulate matter associated with hypertension

Seasoning foods with herbs and spices may help improve heart health

New genetic technique shows the relationship between thyroid function and lipid profile

Research addresses state preemption of local sugar-sweetened beverage taxes

Daytime napping is partly regulated by a person's genes

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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