DNA Methylation News and Research

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DNA methylation is a type of chemical modification of DNA that can be inherited and subsequently removed without changing the original DNA sequence. As such, it is part of the epigenetic code and is also the most well characterized epigenetic mechanism.

Epigenetic Signatures Explain How Andean Highlanders Thrive in Low Oxygen

DNA sequencing technology makes it possible to explore the genome to learn how humans adapted to live in a wide range of environments.

4 Dec 2025

Study Uncovers How Polyploid Plants Harness Transposons for Evolutionary Innovation

Polyploidization, the combination and duplication of genomes, is a major driver of plant evolution and diversification. Yet this process causes "genome shock," leading to rapid activation of transposable elements (TEs).

2 Dec 2025

Scientists Map How Transcription Factors Interpret DNA Sequences

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells.

27 Nov 2025

Novel Mechanism for Epigenetic Patterning in Plants

Every cell within an organism shares an identical genetic blueprint. Their distinct identities stem from epigenetics—precise chemical markers that dictate gene expression.

24 Nov 2025

Discovery Reveals Greater Epigenetic Complexity in Unicellular Life

Multicellular organisms (animals, plants, human) all have the ability to methylate the cytosine © base in their DNA. This process, a type of epigenetic modification, plays an important role in conditions such as cancer and processes such as aging.

19 Nov 2025

New "Ultra-Mild" Method Corrects Cancer DNA Methylation Test Errors

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature Communications. UMBS-seq achieves both accuracy and gentleness, unlocking more reliable cancer biomarker detection.

13 Nov 2025

Biological Effects of Childhood Abuse Uncovered Through Epigenome-Wide Analysis

Child maltreatment, which includes abuse and neglect, is one of the most serious public health concerns worldwide.

16 Oct 2025

Warming Alters Histone Methylation and Iridoid Production in a Traditional Chinese Herb

For centuries, the concept of "geoherbalism" has underscored that traditional Chinese medicines grown in specific regions produce superior therapeutic effects.

10 Oct 2025

Carbon Starvation Drives Metabolic and Epigenetic Reprogramming in Grapevine Cells

Plants rely on sugars not only as energy sources but also as regulators of cellular activities. Carbon starvation disrupts central metabolism, impairs growth, and forces cells to recycle stored resources.

18 Sep 2025

Single-Cell Map Reveals Epigenomic Regulation of Human Fat Tissue

A new study has created the first single-cell map of how DNA is regulated and organized inside different cell-types of human fat tissue.

21 Aug 2025

Amino Acids as Key Mediators in the Tumor Immune Dialogue

The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor and immune cells vie for limited resources.

19 Aug 2025

New Method Enables Human Cells to Initiate Meiosis Outside the Body

More than one-sixth of adults around the world experience infertility in their lifetime. There is a high unmet need not only for increased access to affordable, high-quality fertility care for those in need but, importantly, also for new biomedical solutions that can address the root causes of infertility.

18 Aug 2025