Dementia News and Research

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Dementia is not a specific disease. It is a descriptive term for a collection of symptoms that can be caused by a number of disorders that affect the brain. People with dementia have significantly impaired intellectual functioning that interferes with normal activities and relationships. They also lose their ability to solve problems and maintain emotional control, and they may experience personality changes and behavioral problems, such as agitation, delusions, and hallucinations.

Study Identifies Single Hydrophobic Hotspot Driving Tau Protein Misfolding Propagation

Diseases such as Alzheimer's and frontotemporal dementia are considered neurodegenerative tauopathies, in which tau proteins in the brain misfold and lead to cognitive decline. Until now, it has been unclear how misfolded tau recruits other seemingly healthy tau and causes it to misfold and clump.

13 Oct 2026

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease.

8 Oct 2026

Knocking Out Specific Receptor Genes Prevents Dopaminergic Neuronal Cell Death

The protein alpha-synuclein is abundant in healthy brains and plays an important role in enabling communication between nerve cells.

6 Oct 2026

Gut Bacterial Gene tnaA Converts Dietary Tryptophan Into Toxic Indole

Researchers at LMU have discovered how a metabolite produced by gut bacteria can influence brain damage after stroke.

5 Oct 2026

Experts Extend Lives of Animals By Activating ‘Energy Saver’ Mode

The study, published today in Aging Cell, found strong evidence that triggering a protein governing energy level may help organisms live longer, in some cases by over 25%.

1 Oct 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

25 Sep 2026

Scientists Grow Human Brain Organoids in Cortex-Depleted Mice

Stanford Medicine scientists have chalked up a major advance in growing human brain cells outside of the human brain - and outside of laboratory glassware.

17 Sep 2026

Reading for Pleasure Has Benefits at All Ages – From Improving Health and Wellbeing to Staving off Dementia – Say Scientists

Reading for pleasure – from tucking into a Jane Austen classic to devouring a Heartstopper graphic novel – is linked to better mental health, greater empathy and a lower risk of dementia, say researchers.

15 Sep 2026

Scientists Build a Genetic Score for Alzheimer’s Disease that Works Across Ancestries

Researchers developed a multi-ancestry genetic risk score for Alzheimer's, correlating genetic factors with cognitive performance and brain health markers.

7 Sep 2026

Researchers Struggle Tracking Human Dementia Progress Using Traditional Laboratory Mice

Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the human and animal genomes have raised concerns that some disease mechanisms may not be fully explained by conventional animal models.

31 Aug 2026

Primate-Specific DNA Change Reveals a New Link to Dementia-Related Neurodegeneration

29 Aug 2026

New Study Identifies FAM120A as Critical Protein in Tumor Establishment

Researchers investigating the role of progranulin in cancer progression have previously identified the signaling receptor EphA2 as critical in tumor establishment and potential target to enhance the effectiveness of chemotherapy.

26 Aug 2026

Breakthrough Discovery Pinpoints How Brain Immune Cells Respond to Toxic Cellular Waste

Researchers at the University of California, San Diego, and their colleagues have discovered a critical cellular mechanism that causes brain degeneration in both a rare childhood condition and the far more prevalent Alzheimer’s disease.

17 Aug 2026

New Roadmap Fixes Cellular Waste Accumulation to Halt Brain Degeneration

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

13 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Dementia News and Research

Study Identifies Single Hydrophobic Hotspot Driving Tau Protein Misfolding Propagation

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Knocking Out Specific Receptor Genes Prevents Dopaminergic Neuronal Cell Death

Gut Bacterial Gene tnaA Converts Dietary Tryptophan Into Toxic Indole

Experts Extend Lives of Animals By Activating ‘Energy Saver’ Mode

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

3D Stem-Cell miBrains Model Complex Neurovascular Pathology in Human Tissue

Scientists Grow Human Brain Organoids in Cortex-Depleted Mice

Reading for Pleasure Has Benefits at All Ages – From Improving Health and Wellbeing to Staving off Dementia – Say Scientists

Scientists Build a Genetic Score for Alzheimer’s Disease that Works Across Ancestries

Researchers Struggle Tracking Human Dementia Progress Using Traditional Laboratory Mice

Primate-Specific DNA Change Reveals a New Link to Dementia-Related Neurodegeneration

New Study Identifies FAM120A as Critical Protein in Tumor Establishment

Breakthrough Discovery Pinpoints How Brain Immune Cells Respond to Toxic Cellular Waste

New Roadmap Fixes Cellular Waste Accumulation to Halt Brain Degeneration

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

Scientists Discover Altered 3D Genome Structure in Alzheimer’s Brains

Researchers Discover Surprising Protective Microglia Roles in Dementia

Arc Protein Identified as Driving Tau Spread in Alzheimer's Disease

Research Shows How Alpha Synuclein Interacts With Traditional Alzheimer's Proteins

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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