Drugs News and Research

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Rapid Cell-Free Crystallization Method Reveals 3D Structures of Flexible Sugars

A quick, purification-free method was developed by researchers at Institute of Science Tokyo, to capture the detailed 3D structures of flexible sugar molecules.

31 Oct 2025

New Method Doubles Therapeutic Cell Production for Duchenne Muscular Dystrophy

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

31 Oct 2025

Breakthrough Small Molecule Offers New Hope for Diabetes Treatment

Researchers from the University at Albany and NYU Grossman School of Medicine have found a way to block a key cellular pathway known to drive chronic inflammation and impaired wound healing in people with diabetes.

31 Oct 2025

Unexpected Enzyme Strategy Behind Antibiotic Resistance

Researchers at McGill University have identified two enzymes that employ an unprecedented mechanism to provide resistance, thereby introducing a new dimension in the fight against antimicrobial resistance (AMR), which ranks among the top 10 global public health challenges.

31 Oct 2025

Unlocking the Secrets of Neural Ion Channels

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell-and the molecular gatekeepers that help control them.

30 Oct 2025

RNA Modifications Found to Guide Stem Cell Development into Retinal Cells

Cells contain a blueprint in the form of DNA that dictates what they can make.

29 Oct 2025

Discovery of Glucocorticoid Receptor Multimerization Opens Path to Safer Therapies

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

28 Oct 2025

Breakthrough Cryo-EM Study Maps Herpes Replication Protein in New Detail

An international research team has successfully identified the initial high-resolution structures of the herpes simplex virus origin-binding protein (OBP), which is an essential element in viral DNA replication that has remained structurally uncharacterized for the past forty years.

24 Oct 2025

Research Pinpoints HMGN1 as Cause of Trisomy 21-Related Heart Abnormalities

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

23 Oct 2025

Croatian Scientists Rewrite the Story of Cell Division

Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in fact plays a completely different role in chromosome movement.

22 Oct 2025

Disarming Cancer’s Droplet Hubs to Halt Tumor Growth

In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of fueling progress, they supercharge disease. That's what researchers at the Texas A&M University Health Science Center (Texas A&M Health) have discovered inside the cells of a rare and aggressive kidney cancer.

21 Oct 2025

Tiny DNA ‘Flowers’ Pave the Way for Smart Medical and Environmental Tools

Researchers at the University of North Carolina have created microscopic soft robots shaped like flowers that can change shape and behavior in response to their surroundings, just like living organisms do.

21 Oct 2025

Cancer Reawakens Embryonic Gene Editors to Fuel Tumor Growth

Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks the proteins, or "editors", that control how those genes are read.

17 Oct 2025

PapB Could Make Ozempic-Style Drugs Stronger and Last Longer

Chemistry researchers at the University of Utah have discovered an enzyme referred to as PapB, which is capable of "tying off" therapeutic peptides, drugs resembling proteins, into compact rings, a process termed macrocyclization.

17 Oct 2025

Longevity Gene from Centenarians Reverses Heart Damage in Rare Genetic Disorder

A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.

16 Oct 2025

Framework Evaluating Economic and Environmental Sustainability of Medical Drugs

The production of medical drugs is costly and may negatively impact the environment. Researchers Stefano Cucurachi and Justin Lian have created a framework designed to assist the healthcare system in evaluating the economic and environmental sustainability of medical compounds.

16 Oct 2025