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Bird flu withstands human fever

Avian influenza viruses pose a specific risk to people, as they can multiply at temperatures exceeding a normal fever, which is a defense mechanism used by the body to halt viruses, according to new research conducted by Cambridge and Glasgow universities.

28 Nov 2025

UBQLN2 Liquid Droplets Found to Catalyze Early α-Synuclein Aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease. α-synuclein (α-syn), a misfolded protein, aggregates and forms fibrils, which leads to the formation of LBs.

27 Nov 2025

Scientists Uncover Inner Workings of Biomolecular Condensates Linked to ALS

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

27 Nov 2025

Kinase Inhibitors Found to Trigger Widespread Target Protein Degradation

Protein kinases are the molecular switches of the cell. They control growth, division, communication, and survival by attaching phosphate groups to other proteins.

27 Nov 2025

Biotin Competition in the Nasal Cavity

Research reveals biotin competition in the nasal cavity affects Staphylococcus aureus growth, highlighting potential strategies to combat antibiotic resistance.

26 Nov 2025

Senescent Blood Vessel Cells Drive the Development of Metabolic Disorders

Investigators from the Center for Advanced Gerotherapeutics at Cedars-Sinai found that aged blood vessel cells play a key role in the development of metabolic disorders, including diabetes.

24 Nov 2025

Discovery Offers a Potential Way to Boost Tissue Resident Memory T Cell Numbers

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

24 Nov 2025

Cancer Cells Survive Treatment and Regrow by Hijacking Cell Death Enzyme

The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it.

22 Nov 2025

Innovative Sensor Enables Live Observation of DNA Repair in Living Cells

Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University.

22 Nov 2025

Novel Active Substance Drives Cancer Cells Toward Self Destruction

A new active substance attacks a key protein in tumor cells, leading to complete degradation. In cell experiments, this caused cancer cells to lose their protection and die.

20 Nov 2025

Chaperone-Shielding Mechanism Regulates Protein Glycosylation

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when sugar molecules (glycans) are attached to the maturing protein.

20 Nov 2025

Ultrasound-Controlled Mechanochemical Systems Offer Precision Drug Activation

Conventional drug delivery often relies on passive diffusion or chemical triggers, which may lead to systemic exposure, toxicity, and decreased therapeutic performance.

20 Nov 2025

Innovative Human Cell Model Shows How Melanoma Thrives in the Brain

Using human cells and cutting-edge technology, the team created a three-dimensional (3D) model that accurately simulates the brain invaded by aggressive cancer.

19 Nov 2025

Discovery Reveals Greater Epigenetic Complexity in Unicellular Life

Multicellular organisms (animals, plants, human) all have the ability to methylate the cytosine © base in their DNA. This process, a type of epigenetic modification, plays an important role in conditions such as cancer and processes such as aging.

19 Nov 2025

Researchers Discover Molecular Switch That Helps Breast Cancer Cells Survive Stress

Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust their gene expression to protect themselves.

18 Nov 2025

CRISPR Gene Editing Reverses Chemotherapy Resistance in Lung Cancer

In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in lung cancer. The approach restores drug sensitivity and slows tumor growth.

18 Nov 2025

Blocking a Hidden Tumor Pathway Revives the Immune System

A new study has discovered a molecular signal that tumors exploit to exhaust the T cells meant to destroy them-and how silencing that signal could revive the body's immunity.

18 Nov 2025

Cellarity's AI Model Predicts Drug Induced Liver Injury

Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data.

14 Nov 2025

New Tool Studies Kinase Activity During DNA Damage

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases – enzymes that control nearly all cellular processes – turn on and off inside living cells.

14 Nov 2025

Animal Testing to Be Phased Out Faster as UK Unveils Roadmap for Alternative Methods

Animal testing in science is set to be phased out faster under a new plan to deliver on the government’s manifesto commitment, unveiled by Science Minister Lord Vallance today (Tuesday 11 November).

13 Nov 2025