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New Genetic Discoveries Offer Hope for Osteoarthritis Treatments

Researchers have uncovered multiple new genes and genetic pathways that could lead to repurposing hundreds of existing drugs for osteoarthritis, the most common form of arthritis.

29 Apr 2025

Johns Hopkins Team Identifies Distinct Subtypes of Senescent Skin Cells

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation and promoting diseases while also helping the immune system to heal wounds.

29 Apr 2025

New Drug Combo Shows Promise Against Aggressive Leukemia in Landmark Study

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell differentiation and reducing tumor growth.

28 Apr 2025

Dangerous Synthetic Opioids and Animal Sedatives Not Approved for Human Use Have Been Found in Australia's Wastewater

University of South Australia scientists have developed a highly sensitive method to detect illegal opioids and a veterinary sedative in Australia’s wastewater system, providing a vital early warning tool to public health authorities.

28 Apr 2025

Study Reveals Shared Genetic Basis for Autism Spectrum Disorder and DM1

Researchers from the University of Las Vegas Nevada (UNLV) and The Hospital for Sick Children (SickKids) have discovered a genetic connection between autism spectrum disorder (ASD) and myotonic dystrophy type 1 (DM1), a rare genetic disorder.

23 Apr 2025

Guinea Pigs as a Robust Model for Human Embryo Research

The initial days of human embryo development, referred to as pre-implantation, are crucial.

11 Apr 2025

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

Lab-Grown Lung Cancer Cells to Unlock Targeted Treatments

Scientists at the Cancer Research Manchester Institute have created a new model of Lung Squamous Cell Carcinoma (LUSC), a common type of lung cancer, to study the development, activity, and vulnerabilities of the disease.

9 Apr 2025

Novel Acoustic Technology Accelerates Biomedical Research

Engineers from a University of Bristol spin-out company have developed a new technology that manipulates cells without physical contact, allowing essential tasks—typically performed with bulky lab equipment—to be completed using a compact benchtop device.

7 Apr 2025

New Technology Moves Cells Without Physical Contact

Engineers at a University of Bristol spin-out company have created a new technology that can move cells without touching them, enabling critical tasks that currently require large pieces of lab equipment to be carried out on a benchtop device.

4 Apr 2025

DNA Aptamers Offer Precision Attack Against Leukemia Stem Cells

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

4 Apr 2025

New Brain Organoid Model Reveals How Microglia Respond to Viral Infections

Organoids have revolutionized science and medicine, providing platforms for disease modeling, drug testing, and understanding developmental processes.

4 Apr 2025

Enhanced Oral Vaccination with Competitive Gut Bacteria

Researchers are combining vaccination with targeted colonization of the intestine by innocuous microorganisms to combat bacterial infections. This strategy might signal a sea change in the antibiotic crisis.

4 Apr 2025

Meet Lariocidin: A Game-Changing Antibiotic That Outsmarts Resistance

The study reveals lariocidin, a potent ribosome-targeting antibiotic, with unique mechanisms that could combat drug-resistant bacterial infections effectively.

4 Apr 2025

Bacterium Uses Chemical Radar to Detect and Kill Amoebae

Predator-prey relationships are found in virtually all ecosystems. Even microorganisms in their world, which is invisible to the naked eye, engage in these interactions when fighting for the survival of their species.

3 Apr 2025

New Scientific Article in Nature Linking the Potential Use of NeuroRestore ACD856 for the Treament of Obesity

AlzeCure Pharma AB (publ) (FN STO: ALZCUR), a pharmaceutical company that develops candidate drugs for diseases affecting the nervous system, focusing on Alzheimer's disease and pain, announced today that an article has been published in Nature suggesting the use of NeuroRestore ACD856 in the treatment of obesity.

2 Apr 2025

Novel Protein Analysis Technique Offers Fresh Insights into Immune System Disorders

A study conducted by researchers at Oregon Health & Science University has revealed a novel mechanism by which proteins can be modified within cells. This finding may have significant implications for the understanding of immune system functionality.

1 Apr 2025

Intermittent Fasting Alters Serotonin Levels to Boost Male Mice's Libido

Long-term fasting in 24-hour cycles increases the sex drive of male mice by lowering the concentration of the neurotransmitter serotonin in the brain.

29 Mar 2025

Scientists Capture How Glutamate Opens Neuron Signaling Channels

In an effort to understand how brain cells exchange chemical messages, scientists say they have successfully used a highly specialized microscope to capture more precise details of how one of the most common signaling molecules, glutamate, opens a channel and allows a flood of charged particles to enter.

29 Mar 2025

Researchers Unearth Powerful New Antibiotic from Soil

Researchers at McMaster have made a significant discovery that may be the answer to combating antimicrobial resistance, nearly thirty years after the last time a novel class of antibiotics was brought to market.

28 Mar 2025