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New Pipeline Sharpens Single-Cell Profiling of CAR Immune Therapies

CERTOMICS is a Nextflow-based computational pipeline designed to identify and profile CAR-engineered immune cells using single-cell multiomics data. By integrating gene expression, immune receptor profiling, protein markers, CAR-aware references, and CAR-specific quality control, it supports more standardized analysis of adoptive cellular immunotherapies.

29 Apr 2026

Magnetic Microrobots That Could Transform Cancer Treatment

Cancer treatments and other delicate medical procedures might one day be performed using tiny microrobots that are precisely directed within the body, according to a new magnetic tool created by scientists.

29 Apr 2026

Proxygen Expands Platform Beyond Degradation to Build Next-Generation Induced Proximity Therapeutics

Proxygen, a biotechnology company pioneering the discovery of molecular glue degraders and next-generation proximity-based therapeutics, today publicly announced the expansion of its platform beyond targeted protein degradation to access a broader range of induced proximity therapeutics, while advancing two lead molecular glue degrader programs toward clinical development.

From Proxygen 29 Apr 2026

Drug Development: Development of Dextran Nanoparticles for Stabilizing Delicate Proteins

Nanoscale Research Letters, an open access journal published under Springer Open, presented a study entitled "Development of Dextran Nanoparticles for Stabilizing Delicate Proteins." In this study, a Brookhaven NanoBrook 90Plus Particle Size Analyzer was used to help develop a novel approach to stabilize and encapsulate proteins into dextran nanoparticles.

From Brookhaven Instruments 29 Apr 2026

Obesity Leaves Persistent Epigenetic Marks on Immune Cells

People who live with obesity are 'tagging' a memory of being overweight on a key part of the immune system - leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10 year-long study published in EMBO Reports.

28 Apr 2026

Key Protein Switch Activates Leptospira Virulence and Disease Spread

During infection, pathogens must adapt quickly to the conditions to thrive inside the body. A research team at the University of Basel, Switzerland, has uncovered how a key protein switches on the machinery that enables Leptospira pathogens to survive and cause disease.

28 Apr 2026

Influenza D Virus Shows Potential to Infect Human Cells

The influenza D virus that researchers say has been flying under the radar since its detection in animals in 2011 can vigorously make copies of itself in human cells and lung tissue samples, a new study shows.

27 Apr 2026

Generative AI Model Accelerates Drug Discovery With New Antibiotic Candidate

Researchers at McMaster University have developed a new generative artificial intelligence (AI) model capable of drastically speeding up drug discovery - and, in early tests, it has already designed a brand-new antibiotic.

24 Apr 2026

Fragment-Based Drug Design Accelerates Efficient Discovery of New Medicines

Modern medicine has played a significant role in improving the length and quality of our lives. While many treatments may seem like miracles, they are the result of a lengthy, rigorous research process.

24 Apr 2026

Uncovering a Second Pathway for On-Demand Glycogen Regulation

Researchers at WEHI have uncovered a never-before-seen mechanism that human bodies utilize to control sugar. These discoveries redefine basic biological principles and pave the way for new scientific discoveries.

24 Apr 2026

Painkillers reduce electric shock escape behaviour in lobsters

Analgesic treatments in Norway lobsters show promise in reducing shock responses, emphasizing the need for humane practices in crustacean research and industry.

23 Apr 2026

New VIS-Fbs Technology Offers Sharper Images of Living Cellular Processes

Fluorescent proteins have revolutionized science, enabling researchers to tag and visualize individual molecules in living cells, tissues, and animals.

23 Apr 2026

New Molecular Imaging Technology Illuminates Proteins Inside Living Cells

Fluorescent probes have transformed modern biology by allowing researchers to tag and visualize individual molecules in living cells, tissues, and animals.

22 Apr 2026

New MIND Tool Enables Precise Control of Complex Microbiomes

University of California San Diego researchers have developed a new tool for understanding and modifying any microbiome, including the human microbiome.

22 Apr 2026

Brain Immune Cells Play Key Role in Glioblastoma Tumor Infiltration

Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond the main tumor.

22 Apr 2026

Molecular Keyhole Discovery Unlocks New Target for Pain Therapies

Researchers at VIB, VUB, and KU Leuven have identified a tiny binding site, a molecular 'keyhole', in the TRPM3 ion channel, a crucial sensor in pain signaling.

22 Apr 2026

Scientists Map Human Genes That Control HIV Infection Dynamics

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body.

21 Apr 2026

Study Reveals How Neurons Sense Bacterial Signals in Nematodes

Neural interaction with bacteria, e.g. in the gut microbiome, has important effects on brains of animals from worms to people.

21 Apr 2026

Protein Shape Changes Come Into Focus With LiP-MS and 3D Proteomics

This review explains how LiP-MS detects protein structural changes across whole proteomes, adding functional insight that standard abundance-based proteomics often misses. It also surveys method variants and shows how LiP-MS supports drug-target discovery, disease biomarker research, and the broader framework of “3D proteomics.”

20 Apr 2026

How Mitochondrial Damage Accelerates Stem Cell Aging

Hematopoietic stem cells (HSCs), the cells that produce all blood cell types, start to lose their efficacy as one ages, which eventually reduces the ability to maintain healthy blood and a robust immune system.

17 Apr 2026