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Scientists Identify Molecular Mechanism Behind Persistent Obesity and Weight Relapse

Two enduring biological mysteries have remained unsolved for decades: why almost everyone who loses weight gains it back, no matter how they lost it, and why obesity passes from mother to child at rates that diet and environment cannot explain. Now, scientists from Harrington Discovery Institute at University Hospitals and Case Western Reserve University have identified why.

11 Sep 2026

SMART Researchers Discover First PLP-Dependent Enzyme That Influences Bacterial Protein Production

Researchers from the Singapore-MIT Alliance for Research & Technology’s (SMART) Antimicrobial Resistance (AMR) interdisciplinary research group, alongside collaborators from Massachusetts Institute of Technology (MIT), Nanyang Technological University (NTU Singapore), and institutions in the United States, Poland, and France, have discovered aminovaleramididine synthetase (AvaS), the first identified pyridoxal phosphate (PLP)-dependent enzyme responsible for producing a chemical modification linked to how bacteria respond to metabolic stress.

10 Sep 2026

IU Biologists Find a Hidden Weak Spot in How Bacteria Build the Tails They Use to Move

New research from Indiana University has uncovered a previously unknown vulnerability in how bacteria build the whip-like tails they use to move.

10 Sep 2026

Synchronized Gene Regulatory Pathways Defend C. diff Against Host and Microbiota Threats

The pathogen Clostridioides difficile (C. diff) - a leading cause of hospital-acquired infections - must contend with a variety of threats inside the harsh environment of the gut to survive and grow.

10 Sep 2026

Advanced RNA Sequencing Separates Rare Regenerative Cells From Mature Tissue

Researchers at Weill Cornell Medicine and Hospital for Special Surgery have discovered the unspecialized stem cells that give rise to the body's tendons and ligaments, the tissues connecting muscles and bones.

8 Sep 2026

Research Identifies Microorganisms That Convert Precursors Into Testosterone

Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease often try to reduce testosterone production or block its effects.

7 Sep 2026

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

For decades, natural killer (NK) cells have been classified into two main groups based on surface markers: one specialized for cytokine production and the other for direct killing.

7 Sep 2026

New Understanding of Brain Circuitry Genes Opens Door for Targeted OCD Therapies

A Rutgers-led international team co-authored a study, which was published in Nature Neuroscience, revealing 36 genes significantly increasing the risk for obsessive-compulsive disorder (OCD) and chronic tic disorders. This research offers the most comprehensive biological insight into the development of these conditions and potential future treatments.

4 Sep 2026

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail.

2 Sep 2026

Research Evaluates How Protein Production Speeds Impact PROTAC Success

The way cancer-causing proteins accumulate in tumors may influence how effectively a promising new generation of medicines can remove them, a study suggests.

2 Sep 2026

Cell Study Unveils Method to Spot Tiny Molecular Protein Fluctuations

Imagine a brain teaser where the challenge is to spot the difference between two nearly identical sandcastles. The only difference? The removal of three grains of sand.

2 Sep 2026

Scientists Find Cancer Gene Forcing Zombie Cells to Cause Aging

In a tale of identities as divergent as "The Prince and the Pauper," a well-known cancer-causing gene also influences cells in a zombie-like state meant to prevent cancer.

31 Aug 2026

Next-Generation RNA Therapeutic Approach Offers Hope for Treating Diverse Genetic Diseases

Researchers at the University of Toronto have developed a next-generation RNA therapeutic approach with the potential to treat a wide range of genetic diseases that share certain disease-causing mutations.

28 Aug 2026

New Model Accelerates Design of Protein Degrader Drugs

A team of Weill Cornell Medicine investigators has developed a computer model that will help scientists more efficiently develop protein-destroying therapies, a newer type of treatment that is particularly promising for cancer.

27 Aug 2026

Scientists Reconstruct Prehistoric Mammalian Peptides to Combat Global Antibiotic-Resistance

University of Oregon biologists have resurrected prehistoric proteins up to 160 million years old that carry natural antimicrobial properties.

26 Aug 2026

Fruit Fly Olfactory Processing Inspires Energy Efficient Scent Classification Algorithms

In the animal kingdom, energy conservation is essential for survival. That's why our brains have evolved to be extremely energy and resource efficient at storing and processing information.

25 Aug 2026

Advanced Peptides Overcome Human Biological Barriers in New Cancer Medicine

Influencers across TikTok and the internet have been touting peptides as a beauty and health cure-all, with some claiming they can de-age you or significantly transform your appearance.

25 Aug 2026

New Open-Access Protein Atlas Aims to Streamline Future Drug Development

For a new drug to work in the human body, it must make its way to the exact cell type where it's needed and then, in many cases, get inside the cells.

24 Aug 2026

New Computational Tool Estimates Cell Age by Analyzing Gene Activity Patterns

Scientists at Karolinska Institutet and Stockholm University have created an innovative tool that determines cellular biological age through gene activity analysis.

24 Aug 2026

Mice Studies Prove Engineered Molecules Eradicate Tumors Within Eleven Days

A two-headed molecule designed by Stanford Medicine researchers hijacks one of the most common protein drivers of B-cell lymphoma, flipping it from its role as a promoter of cell growth into an arbiter of cell death.

22 Aug 2026

Drugs News and Research

Scientists Identify Molecular Mechanism Behind Persistent Obesity and Weight Relapse

SMART Researchers Discover First PLP-Dependent Enzyme That Influences Bacterial Protein Production

IU Biologists Find a Hidden Weak Spot in How Bacteria Build the Tails They Use to Move

Synchronized Gene Regulatory Pathways Defend C. diff Against Host and Microbiota Threats

Advanced RNA Sequencing Separates Rare Regenerative Cells From Mature Tissue

Research Identifies Microorganisms That Convert Precursors Into Testosterone

Research Maps Complex Molecular Rules Governing Specialized Tumor Immunity

New Understanding of Brain Circuitry Genes Opens Door for Targeted OCD Therapies

Targeting EFHD1 Protein Prevents Severe Obesity-Related Metabolic Liver Damage

Research Evaluates How Protein Production Speeds Impact PROTAC Success

Cell Study Unveils Method to Spot Tiny Molecular Protein Fluctuations

Scientists Find Cancer Gene Forcing Zombie Cells to Cause Aging

Next-Generation RNA Therapeutic Approach Offers Hope for Treating Diverse Genetic Diseases

New Model Accelerates Design of Protein Degrader Drugs

Scientists Reconstruct Prehistoric Mammalian Peptides to Combat Global Antibiotic-Resistance

Fruit Fly Olfactory Processing Inspires Energy Efficient Scent Classification Algorithms

Advanced Peptides Overcome Human Biological Barriers in New Cancer Medicine

New Open-Access Protein Atlas Aims to Streamline Future Drug Development

New Computational Tool Estimates Cell Age by Analyzing Gene Activity Patterns

Mice Studies Prove Engineered Molecules Eradicate Tumors Within Eleven Days

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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