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Metastatic Lung Cancer Cells Cozy Up to Neurons and Form Synapses

Small cell lung cancer cells that metastasize to the brain cozy up to neurons and form working electrical connections, called synapses, according to an upcoming study led by Stanford Medicine researchers.

11 Sep 2025

Specialized Protein Structures Essential for Correct Sperm Function

There are many potential causes of infertility, and it can be challenging to pin down just what the problem is when a couple is having trouble getting pregnant.

11 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

Stress Reshapes Brain Cells and Alters Activity in Mice

Canadian researchers show that stress modifies the morphology of brain cells in mice, directly influencing the rodents' level of physical activity.

5 Sep 2025

First Complete Map of Plant Stress Response System Unveiled

Researchers have created the world's first complete map of a crucial cellular system that helps plants respond to stress.

4 Sep 2025

Tackling KRAS Mutations Unlocks New Hope for Pancreatic Cancer Patients

Accounting for nearly 90% of all pancreatic cancers, pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of just 13%. Late-stage diagnosis, limited surgical options, and toxic chemotherapy regimens contribute to its poor outcomes.

2 Sep 2025

Fruit Fly Study Highlights Benefits of Heterogeneity Among Cells

All living beings, big or small, are formed through the hard work of many different cells. To keep the body ready for any challenge, cells need to be dynamic.

29 Aug 2025

New "DNA Organizer" Found to Be Essential for Sperm Stem Cell Development

A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells that give rise to sperm.

27 Aug 2025

New Computational Tool Enhances Cancer Tissue Analysis for Personalized Treatment

Scientists at the Icahn School of Medicine at Mount Sinai have developed a powerful new computational tool that could transform how cancer tissues are analyzed and help pave the way for more personalized treatments.

27 Aug 2025

Cryo-Optical Microscopy Captures Instantaneous Snapshots of Cellular Waves

Optical microscopy is a key technique for understanding dynamic biological processes in cells, but observing these high-speed cellular dynamics accurately, at high spatial resolution, has long been a formidable task.

25 Aug 2025

Organ Development Shaped Equally by Mechanics and Biochemistry

A new study looks at the physical forces that help shape developing organs. Scientists in the past believed that the fast-acting biochemistry of genes and proteins is responsible for directing this choreography.

22 Aug 2025

Comprehensive Guide Sets New Standards for Plant Fluorescence Imaging

A team of expert scientists led by Kirk Czymmek, PhD, director of the Advanced Bioimaging Laboratory at the Donald Danforth Plant Science Center and Heather E. McFarlane, assistant professor at the University of Toronto and collaborators from the Danforth Center, University of Leeds (UK), University of Massachusetts (Amherst), University of California - Davis, University of Naples Federico II, University of Minnesota and Université de Montréal, have authored a comprehensive guide to elevate the quality, transparency, and reproducibility of fluorescence microscopy in plant research. The guide was recently published in the journal Plant Cell, "Best Practices in Plant Fluorescence Imaging and Reporting: A Primer"

22 Aug 2025