Epigenetics News and Research

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Epigenetics is the study of chemical reactions that influence gene expression, through activation or deactivation of genes at specific times and locations.

RNA Modifications Found to Guide Stem Cell Development into Retinal Cells

Cells contain a blueprint in the form of DNA that dictates what they can make.

29 Oct 2025

Developing GoT-Multi to Track Cancer Evolution and Treatment Resistance

A novel tool created by researchers at Weill Cornell Medicine and the University of Adelaide has improved the capacity to monitor multiple gene mutations while concurrently recording gene activity in individual cancer cells.

13 Oct 2025

Warming Alters Histone Methylation and Iridoid Production in a Traditional Chinese Herb

For centuries, the concept of "geoherbalism" has underscored that traditional Chinese medicines grown in specific regions produce superior therapeutic effects.

10 Oct 2025

Takara Bio USA, Inc. Announces a Series of Updates to Its Spatial Biology Product Portfolio, Extending Its Innovation With a New Class of Spatial Technology

Takara Bio USA, Inc. ("Takara Bio USA"), a wholly owned subsidiary of Takara Bio Inc. ("Takara Bio"), today announced a series of updates to its spatial biology product portfolio, extending its innovation with a new class of spatial technology.

From Takara Bio USA, Inc. 9 Oct 2025

EZH2 Inhibition Restores Order in Cancer Cell Division and Reduces Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from spreading.

6 Oct 2025

Gut Microbes Influence Human Genes and Health

The trillions of microbes that live in the human gut may play a bigger role in health than previously thought, according to a new research by the University of Hawaiʻi at Mānoa.

24 Sep 2025

Blocking SUMO2 Protein may be a Winning Strategy Against Synovial Sarcoma

In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay.

8 Sep 2025

New RNA Sequencing Technology Uncovers Molecular Drivers of Cellular Differentiation

Researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have documented their use of a new RNA sequencing technology to uncover molecular drivers of cellular differentiation that could lead to better regenerative therapies.

8 Aug 2025

Precision Control of Gene Switches Offers Hope for Tackling Inflammatory Diseases

Genes, fragments of DNA located on our chromosomes, control much of what happens in cells. Each cell activates only the genes it needs, silencing the rest through molecular "switches" present on each gene.

18 Jul 2025

New Metabolic Map Reveals How Blood Stem Cells Age and Become Diseased

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zürich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous.

16 Jul 2025

Reinvigorating T Cells Offers Hope for More Effective Cancer Immunotherapy

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

8 Jul 2025

RNases Play Pivotal Role in Shaping the Molecular Foundation of Mendelian Disorders

A new review brings to light the pivotal role of ribonucleases (RNases) in shaping the molecular foundation of Mendelian disorders.

26 Jun 2025

Fusion Genes Emerge as Key Drivers in Cancer Development

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with altered functions, often driving tumor progression.

25 Jun 2025

Combating Tumor Resistance and Exhaustion in Lymphoma

The study reviews CAR-T cell advancements in lymphoma treatment, addressing T cell exhaustion and tumor immune evasion with next-generation CAR modifications.

24 Jun 2025

RNA Editing and Transcriptional Switching Shape Fungal Antiviral Response

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely unknown, especially in the case of fungus-virus pathogen systems.

24 May 2025

How RNA-Binding Proteins and Circular RNAs Shape Tumor Biology

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

13 May 2025

Precision Mitochondrial DNA Editing Emerges as a Breakthrough in Neurological Care

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

13 May 2025

Grapevine Cells Show Epigenetic Shifts in Response to Sugar Starvation

Plants face constant challenges from fluctuating nutrient availability, which disrupts their growth and survival.

10 May 2025

Grapevine Cells Reveal Epigenetic Response to Sugar Starvation

Plants face constant challenges from fluctuating nutrient availability, which disrupts their growth and survival.

6 May 2025

Transitioning Pancreatic Cells Retain Cancer Linked Epigenetic Marks

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

25 Apr 2025