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Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation.

1 Oct 2026

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But until now, scientists weren't quite sure how the protein gets where it needs to go to keep genes bound up so they aren't activated.

1 Oct 2026

Singlet Oxygen Oxidizes Electron-Rich Base Pairs to Cleave Bacterial DNA

Engineers have developed a new approach for turning ordinary water into a weapon against antibiotic-resistant bacteria, according to a study publishing September 30 in the Cell Press journal Chem Catalysis.

1 Oct 2026

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within tissue.

30 Sep 2026

Decoding the Mechanisms Behind Long-Term Epigenetic Gene Regulation Shifts

The transmission of biological traits from one generation to the next is generally attributed to DNA. But could some changes be passed on without altering the DNA sequence?

30 Sep 2026

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

29 Sep 2026

Oncogene-Induced Senescence Exhibits Dual Role in Tumor Suppression and Progression

Researchers at NYU Abu Dhabi have discovered that a single cancer-causing gene can trigger different responses in cells, with some helping to prevent tumors while others may contribute to their development.

29 Sep 2026

Study Links OCA2 Gene Mutations to Non-Melanin Ocular Developmental Defects

Tiny, striped zebrafish are helping scientists trace how a gene linked to albinism influences eye development, work that may ultimately help explain some of the vision problems experienced by people with the condition and guide the search for new treatments.

29 Sep 2026

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

The adult human heart is a reliable and resilient engine fueling our everyday lives while also being responsive enough to supercharge a Usain Bolt sprint or sustain a three-week bike race in the French Alps and Pyrenees.

29 Sep 2026

New Insights Into How Toxoplasma Parasites Trigger Host Cell Invasion

Before the parasite Toxoplasma gondii can invade a cell, it has to know it has reached the right place. New research from the Whitehead Institute reveals that the parasite doesn't simply recognize a ready-made doorway into the cell. Instead, it helps create the conditions for its own entry.

28 Sep 2026

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

A review published in Genes & Diseases highlights the complex interplay between protein arginine methylation and ubiquitination, two forms of protein modification that can profoundly influence cancer development, progression and treatment response. The article brings together current understanding of how these interconnected molecular processes regulate proteins involved in cancer and identifies opportunities for future therapeutic approaches.

28 Sep 2026

AI Decodes Spatial DNA Packaging Patterns Invisible to Researchers

Aging progressively affects the functioning of our body and, among other things, deteriorates the ability of the hematopoietic system- the set of organs and tissues responsible for producing blood cells- to maintain adequate blood cell production.

28 Sep 2026

Genomic Datasets Provide Molecular Foundations for Bat Disease Tolerance

Laurel Yohe, Ph.D., assistant professor of bioinformatics at The University of North Carolina at Charlotte, is among the co-authors of a landmark study of bat genomes published this week in Nature.

28 Sep 2026

Viral Metagenomics Uncovers Distinct Replication Machinery in Plateau Wetland Soils

Wetlands are well known for filtering water, storing carbon, and supporting biodiversity. Yet much of their microbial genetic diversity remains unexplored, particularly in high-altitude ecosystems.

26 Sep 2026

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

Gut microbiota influences multiple aspects of host physiology, including metabolic and immune functions. Many metabolites produced by gut bacteria can cross the intestinal epithelium (which the bacteria may not be able to cross) and enter host tissues, providing a pathway through which microbial activity can influence host physiology.

25 Sep 2026

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.

25 Sep 2026

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Three adenosine receptor subtypes that normally send different signals were found to converge on a common pathway that activates cardiac fibroblasts, the scar-forming cells in the heart. Blocking the receptors together produced a much stronger antifibrotic effect than blocking them one at a time.

25 Sep 2026

Genes News and Research

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Singlet Oxygen Oxidizes Electron-Rich Base Pairs to Cleave Bacterial DNA

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Decoding the Mechanisms Behind Long-Term Epigenetic Gene Regulation Shifts

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

Oncogene-Induced Senescence Exhibits Dual Role in Tumor Suppression and Progression

Study Links OCA2 Gene Mutations to Non-Melanin Ocular Developmental Defects

Single-Cell Sequencing Confirms Epigenetic Remodeling Across Diverse Cardiac Cell Types

New Insights Into How Toxoplasma Parasites Trigger Host Cell Invasion

Post-Translational Modification Crosstalk Regulates Oncogenic Protein Stability and Activity

AI Decodes Spatial DNA Packaging Patterns Invisible to Researchers

Genomic Datasets Provide Molecular Foundations for Bat Disease Tolerance

Viral Metagenomics Uncovers Distinct Replication Machinery in Plateau Wetland Soils

Engineered E. coli Strains Validate Putrescine Uptake and Systemic Host Conversion

Cancer Cells Hijack Embryonic Repair Mechanisms to Seed Liver Metastases

Multi-Receptor Blocking Achieves Superior Antifibrotic Response Over Single-Receptor Inhibition

Garvan Researchers Uncover Genetic Causes of Inherited Muscle Disease

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

A Tiny Worm Helps Scientists Unravel a Genetic Clue to Kidney Disease

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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