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Disrupted Circadian Rhythms Alter Gene Activity in Alzheimer’s Disease

Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.

24 Oct 2025

Hidden RNA Inside a Gene Solves Decades-Old Telomere Mystery in Roundworms

An international research team led by Hiroki Shibuya at RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has solved a genetic mystery and revealed a previously unknown way that DNA can control what cells do.

24 Oct 2025

Research Pinpoints HMGN1 as Cause of Trisomy 21-Related Heart Abnormalities

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

23 Oct 2025

Biological Bulldozer Mechanism Explains Ants’ Powerful Sense of Smell

Ants have evolved an acute sense of smell, which requires each sensory neuron to choose one scent receptor out of hundreds.

23 Oct 2025

Cracking the Code of T Cell Expansion Inside Tumors

The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key to the success of modern day cancer immunotherapies.

22 Oct 2025

Disarming Cancer’s Droplet Hubs to Halt Tumor Growth

In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of fueling progress, they supercharge disease. That's what researchers at the Texas A&M University Health Science Center (Texas A&M Health) have discovered inside the cells of a rare and aggressive kidney cancer.

21 Oct 2025

Decoding the Genetic Network Behind Soybean Shade Tolerance

In intercropping systems, soybeans grown beneath tall maize plants experience severe shading that disrupts photosynthesis, weakens stems, and limits yield.

21 Oct 2025

Synthetic Biology Unlocks New Ways to Engineer Plant–Microbe Interactions

By integrating engineering principles with plant biology, this review highlights how redesigned genetic pathways and plant-based biosensors can deepen understanding of plant responses to both harmful and beneficial microbes.

17 Oct 2025

Cancer Reawakens Embryonic Gene Editors to Fuel Tumor Growth

Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks the proteins, or "editors", that control how those genes are read.

17 Oct 2025

Molecular Brake SlKNU Regulates Flower Formation and Fruit Development in Tomato

Floral meristems (FMs) are small clusters of stem cells that orchestrate flower formation and ultimately determine the size and structure of the fruit.

17 Oct 2025

Study Uncovers Hundreds of New Viruses Living Inside the Gut Bacteria

Hundreds of new viruses living inside bacteria within our gut have been discovered in an international study led by Professor Jeremy J. Barr from Monash University's School of Biological Sciences and Associate Professor Sam Forster from Hudson Institute of Medical Research.

16 Oct 2025

Research Reveals Transcriptional Mechanism Behind Salt Tolerance in Watermelon

High soil salinity disrupts water absorption, ion balance, and photosynthesis in plants, leading to growth inhibition and yield loss.

16 Oct 2025

Longevity Gene from Centenarians Reverses Heart Damage in Rare Genetic Disorder

A new breakthrough in a rare genetic disease which causes children to age rapidly has been discovered using 'longevity genes' found in people who live exceptionally long lives - over 100 years old.

16 Oct 2025

Biological Effects of Childhood Abuse Uncovered Through Epigenome-Wide Analysis

Child maltreatment, which includes abuse and neglect, is one of the most serious public health concerns worldwide.

16 Oct 2025

New Insights into rRNA Motifs and Nervous System Genes

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life.

15 Oct 2025

Auxin Controls Grape Berry Firmness Through a Hierarchical Gene Cascade

Grape berry softening is a crucial physiological transition that affects postharvest storage, transport, and flavor.

15 Oct 2025

Pioneering Approach Restores Sperm Production and Fertility in Mouse Model

For many couples facing infertility, medicine offers a range of solutions. But for men with non-obstructive azoospermia (NOA)-a genetic condition where sperm production stalls-options remain limited.

15 Oct 2025

Discovery Reveals How Microbes Evolve Rapidly Inside the Human Gut

Everywhere you go, you carry a population of microbes in your gastrointestinal tract that outnumber the human cells making up your body.

14 Oct 2025

RfaH Identified as Key to Bacterial Survival in Hostile Environments

Researchers at Umeå University have identified a key molecular player that helps bacteria survive the hostile environment inside the body.

10 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025