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Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

Cysteine is one of the main building blocks that cells use to make proteins. But this amino acid is a double-edged sword–too much cysteine is toxic to the cell.

24 Sep 2026

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues have discovered that a type of rogue DNA found in aggressive cancers has a hidden structural weakness - and that blocking a single repair protein can cause it to fall apart, suggesting a new therapeutic opportunity.

24 Sep 2026

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

The Human Genome Project was launched in 1990, preceded by decades of breakthroughs in genetics. It eventually gave us a sequence of the human genome.

24 Sep 2026

Mitochondrial RNA May Explain How Tumors Become Resistant to Immunotherapy

Research highlights mitochondrial RNA's influence on interferon signaling, linking chronic exposure to tumor growth and offering new avenues for immunotherapy.

22 Sep 2026

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Cysteine is one of the main building blocks that cells use to make proteins.

22 Sep 2026

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

A team of researchers led by Professor Haruhisa Inoue (Center for iPS Cell Research and Application, Kyoto University) and Professor Yuishin Izumi (Tokushima University) demonstrated that adenine base editing can correct a disease-causing genetic mutation and alleviate neurodegeneration in hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P), providing proof of concept for a precision gene therapy for inherited motor neuron diseases.

21 Sep 2026

Study Links Maternal Infections to Fetal Brain Development

Research shows maternal infections affect fetal brain development, with immune responses linked to autism spectrum disorder and other neurodevelopmental issues.

18 Sep 2026

Integrated DNA Technologies and Aldevron Launch New Cas9 mRNA Solutions to Accelerate Path From Gene Editing Research to Development

Danaher companies Integrated DNA Technologies (IDT), a global leader in genomics, and Aldevron, a premier manufacturing partner for DNA, RNA, and protein, today announced the launch of research grade S.p. Cas9 mRNA in wild type and SpyFi™ high-fidelity formats.

From Integrated DNA Technologies 18 Sep 2026

Single-Cell Multiomics Model Decodes Enhancer Networks in Rare Cell Populations

Understanding gene regulation may be the key to interpreting human disease genetics. Genes are regulated in part by stretches of DNA called enhancers, which define when, where, and how strongly each gene is turned on.

17 Sep 2026

Engineered Prime Editing Strategy Integrates Gene-Sized Payloads Into Living Human Genomes

Genomic editing holds great potential yet continues to have its limitations. Most current methods either rely on untargeted gene delivery or short DNA edits that need to be individualized to each patient.

17 Sep 2026

Nabsys 2.0 Platform Detects Key Structural Variants and Copy Number Changes in Leukemia

Nabsys 2.0, LLC ("Nabsys"), a pioneer in Electronic Genome Mapping (EGM), today announced results from a proof-of-principle study led by researchers at Augusta University evaluating the Nabsys OhmX™ Platform for cytogenomic analysis of hematologic malignancies.

17 Sep 2026

Research Team Uncovers Physical Genome Interactions Governing Regenerative Gene Expression Programs

After an injury, DNA not only alters its activity but also the way it is organized spatially within the cell nucleus.

17 Sep 2026

New Surveillance Tool Uses Mosquito Waste to Track Emerging Pathogens

When public health researchers want to know whether diseases such as COVID-19 or polio are circulating in a community, they can look for genetic evidence in wastewater.

16 Sep 2026

Research Exposes Molecular Mechanisms Dampening CD8+ T Cell Functional Efficacy

A research team led by Prof. ZHOU Xuyu from the Institute of Microbiology of the Chinese Academy of Sciences (CAS), in collaboration with researchers from Beijing Ditan Hospital and Capital Medical University, has identified ANKRD11 as a key regulator that reduces the activity of CD8+ T cells during chronic hepatitis B virus (HBV) infection and cancer.

15 Sep 2026

Hidden DNA Sequences Outside Human Genes Contain Signatures of Complex Schizophrenia

Researchers at the University of Oslo have mapped which parts of our DNA carry the inherited differences behind complex traits and disorders.

15 Sep 2026

Researchers Identify Genetic Factors Enabling Deadly E. coli Strains to Infect

Researchers from Tokyo Metropolitan University have identified how certain dangerous bacteria are spread.

12 Sep 2026

Unlocking the Genetic History of Grasses for Future Food Security Solutions

An international team of scientists, including Donald Danforth Plant Science Center Member Emerita Elizabeth "Toby" Kellogg, PhD, has produced a chromosome-level genome assembly that offers a new view of the earliest evolution of grasses, the plant family that includes many of the world's most important food crops.

11 Sep 2026

Multi-Omic Integration Reveals Novel Gene-Disease Links in Undiagnosed Rare Conditions

Researchers from Queen Mary University of London, the Berlin Institute of Health at Charité (BIH) and Genomics England have shown that measuring proteins in the blood can provide important additional clues about the effects of genetic variants, helping to identify diagnoses and potential new disease-causing genes that genome sequencing alone has been unable to resolve.

10 Sep 2026

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

A study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found that new cutting-edge techniques can accurately edit genes in human embryos-giving scientists indispensable tools for understanding normal human development-but has also uncovered important risks that currently preclude the use of the techniques in the clinic.

10 Sep 2026

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

Although DNA repair is one of the fundamental processes required for normal human embryonic development, little has been known about how it operates during the earliest stages of development.

10 Sep 2026

Genome News and Research

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

Mitochondrial RNA May Explain How Tumors Become Resistant to Immunotherapy

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

Study Links Maternal Infections to Fetal Brain Development

Integrated DNA Technologies and Aldevron Launch New Cas9 mRNA Solutions to Accelerate Path From Gene Editing Research to Development

Single-Cell Multiomics Model Decodes Enhancer Networks in Rare Cell Populations

Engineered Prime Editing Strategy Integrates Gene-Sized Payloads Into Living Human Genomes

Nabsys 2.0 Platform Detects Key Structural Variants and Copy Number Changes in Leukemia

Research Team Uncovers Physical Genome Interactions Governing Regenerative Gene Expression Programs

New Surveillance Tool Uses Mosquito Waste to Track Emerging Pathogens

Research Exposes Molecular Mechanisms Dampening CD8+ T Cell Functional Efficacy

Hidden DNA Sequences Outside Human Genes Contain Signatures of Complex Schizophrenia

Researchers Identify Genetic Factors Enabling Deadly E. coli Strains to Infect

Unlocking the Genetic History of Grasses for Future Food Security Solutions

Multi-Omic Integration Reveals Novel Gene-Disease Links in Undiagnosed Rare Conditions

Advanced Gene Editing Provides Essential Tool for Studying Early Human Embryonic Development

Human Embryos Repair Single-Strand DNA Damage Reliably but Fail at Double-Strand Breaks

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