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Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation.

1 Oct 2026

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

A protein that's essential to every cell's ability to turn off unnecessary genes is well known for its key function of compacting genes and its connection to cancer when it undergoes mutation. But until now, scientists weren't quite sure how the protein gets where it needs to go to keep genes bound up so they aren't activated.

1 Oct 2026

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within tissue.

30 Sep 2026

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

29 Sep 2026

Researchers Develop Metax Profiler for Accurate Microbial Taxonomic Identification

HZI team develops a computational tool for accurate identification and abundance estimation of microorganisms in complex samples.

29 Sep 2026

Genomic Datasets Provide Molecular Foundations for Bat Disease Tolerance

Laurel Yohe, Ph.D., assistant professor of bioinformatics at The University of North Carolina at Charlotte, is among the co-authors of a landmark study of bat genomes published this week in Nature.

28 Sep 2026

Viral Metagenomics Uncovers Distinct Replication Machinery in Plateau Wetland Soils

Wetlands are well known for filtering water, storing carbon, and supporting biodiversity. Yet much of their microbial genetic diversity remains unexplored, particularly in high-altitude ecosystems.

26 Sep 2026

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

Cysteine is one of the main building blocks that cells use to make proteins. But this amino acid is a double-edged sword–too much cysteine is toxic to the cell.

24 Sep 2026

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues have discovered that a type of rogue DNA found in aggressive cancers has a hidden structural weakness - and that blocking a single repair protein can cause it to fall apart, suggesting a new therapeutic opportunity.

24 Sep 2026

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

The Human Genome Project was launched in 1990, preceded by decades of breakthroughs in genetics. It eventually gave us a sequence of the human genome.

24 Sep 2026

Mitochondrial RNA May Explain How Tumors Become Resistant to Immunotherapy

Research highlights mitochondrial RNA's influence on interferon signaling, linking chronic exposure to tumor growth and offering new avenues for immunotherapy.

22 Sep 2026

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Cysteine is one of the main building blocks that cells use to make proteins.

22 Sep 2026

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

A team of researchers led by Professor Haruhisa Inoue (Center for iPS Cell Research and Application, Kyoto University) and Professor Yuishin Izumi (Tokushima University) demonstrated that adenine base editing can correct a disease-causing genetic mutation and alleviate neurodegeneration in hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P), providing proof of concept for a precision gene therapy for inherited motor neuron diseases.

21 Sep 2026

Study Links Maternal Infections to Fetal Brain Development

Research shows maternal infections affect fetal brain development, with immune responses linked to autism spectrum disorder and other neurodevelopmental issues.

18 Sep 2026

Integrated DNA Technologies and Aldevron Launch New Cas9 mRNA Solutions to Accelerate Path From Gene Editing Research to Development

Danaher companies Integrated DNA Technologies (IDT), a global leader in genomics, and Aldevron, a premier manufacturing partner for DNA, RNA, and protein, today announced the launch of research grade S.p. Cas9 mRNA in wild type and SpyFi™ high-fidelity formats.

From Integrated DNA Technologies 18 Sep 2026

Single-Cell Multiomics Model Decodes Enhancer Networks in Rare Cell Populations

Understanding gene regulation may be the key to interpreting human disease genetics. Genes are regulated in part by stretches of DNA called enhancers, which define when, where, and how strongly each gene is turned on.

17 Sep 2026

Engineered Prime Editing Strategy Integrates Gene-Sized Payloads Into Living Human Genomes

Genomic editing holds great potential yet continues to have its limitations. Most current methods either rely on untargeted gene delivery or short DNA edits that need to be individualized to each patient.

17 Sep 2026

Nabsys 2.0 Platform Detects Key Structural Variants and Copy Number Changes in Leukemia

Nabsys 2.0, LLC ("Nabsys"), a pioneer in Electronic Genome Mapping (EGM), today announced results from a proof-of-principle study led by researchers at Augusta University evaluating the Nabsys OhmX™ Platform for cytogenomic analysis of hematologic malignancies.

17 Sep 2026

Research Team Uncovers Physical Genome Interactions Governing Regenerative Gene Expression Programs

After an injury, DNA not only alters its activity but also the way it is organized spatially within the cell nucleus.

17 Sep 2026

New Surveillance Tool Uses Mosquito Waste to Track Emerging Pathogens

When public health researchers want to know whether diseases such as COVID-19 or polio are circulating in a community, they can look for genetic evidence in wastewater.

16 Sep 2026

Genome News and Research

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Single-Molecule Optical Tweezers Visualize Real-Time Dynamic Protein and DNA Interactions

Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Targeted Y Chromosome Deletions Disrupt Key Cellular Immune Response Pathways

Researchers Develop Metax Profiler for Accurate Microbial Taxonomic Identification

Genomic Datasets Provide Molecular Foundations for Bat Disease Tolerance

Viral Metagenomics Uncovers Distinct Replication Machinery in Plateau Wetland Soils

Scientists Discover Why High Levels of the Amino Acid Cysteine Are Toxic to Cells

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers Simulate Microgravity to Isolate Gravity's Impact on Human Chromatin

Mitochondrial RNA May Explain How Tumors Become Resistant to Immunotherapy

Blocking Mitochondrial Iron Transport Protects Cells Against Elevated Cysteine Toxicity

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

Study Links Maternal Infections to Fetal Brain Development

Integrated DNA Technologies and Aldevron Launch New Cas9 mRNA Solutions to Accelerate Path From Gene Editing Research to Development

Single-Cell Multiomics Model Decodes Enhancer Networks in Rare Cell Populations

Engineered Prime Editing Strategy Integrates Gene-Sized Payloads Into Living Human Genomes

Nabsys 2.0 Platform Detects Key Structural Variants and Copy Number Changes in Leukemia

Research Team Uncovers Physical Genome Interactions Governing Regenerative Gene Expression Programs

New Surveillance Tool Uses Mosquito Waste to Track Emerging Pathogens

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