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Cornell Researchers Develop Safer CRISPR Technique Using DNA Nicks

Researchers at Cornell University have developed a safer and more precise way to study how genes function in living tissues by refining a recently developed CRISPR-based genetic technique in fruit flies, enabling researchers to better study how genes contribute to development and disease.

28 May 2026

Cells Sense Abnormal RNA Patterns to Silence Jumping Genes

Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell survival if left unchecked. Cells control these "jumping genes" by silencing them, but little was known about how cells recognize and defend themselves from invading transposons.

27 May 2026

Researchers Link Brain Extracellular Matrix Deterioration to Postmenopausal Memory Loss

A largely overlooked space between cells in women's brains may hold the key to understanding memory loss tied to estrogen decline after menopause, reports a new preclinical Northwestern Medicine study.

26 May 2026

Dividing Cells Replicate Chromosomal Errors to Trigger Advanced Tumor Progression and Growth

Megan Sweet slices tumors.

26 May 2026

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that protect and repair DNA in cells.

22 May 2026

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying people at higher risk of cancer or even, potentially stopping malignant transformation.

21 May 2026

New Epigenetic Study Discovers Inheritance Patterns That Defy Mendel's Laws

Scientists have long known that the DNA code in genes is not the only way to pass genetic traits from parents to offspring.

21 May 2026

Protein Plays Dual Role by Silencing Thousands of Genes While Keeping Vital Ones Active

The causes of male infertility can be hard to diagnose, with many tests failing to detect genetic defects. Sometimes, infertility doesn't even involve the genes themselves. It can arise from improper folding of the father's DNA in the sperm. If a couple conceives, this mispackaged DNA can damage the lifelong health of the child.

21 May 2026

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

Researchers at the Icahn School of Medicine at Mount Sinai, Bristol Myers Squibb, and the University of Oxford have discovered a way to give worn-out immune cells a second wind in the fight against multiple myeloma.

20 May 2026

Cell Study Challenges Long-Standing View That Individual Human Genomes Evolve Independently

Scientists at Children's Medical Center Research Institute at UT Southwestern (CRI) have discovered that large pieces of DNA can transfer directly between human cells, and the DNA can persist and change how the recipient cell functions.

20 May 2026

Novel Formicitoxins Found in Carpenter Ant Venom Offer Drug Discovery Impetus

The venom of forest ants and horse ants contains numerous substances that protect the insects from pathogens. Researchers at Martin Luther University Halle-Wittenberg (MLU) and Freie Universität Berlin have succeeded for the first time in identifying and characterizing these novel antimicrobial substances in the insects' venom.

19 May 2026

Novel Breast Cancer DNA Signatures Reveal Link Between Genomes and Tumor Immunity

A study led by Dr Jason Pitt, Principal Investigator at the Cancer Science Institute of Singapore (CSI Singapore), has identified eight new "signatures" of DNA patterns (gains and/or losses) in breast cancer.

19 May 2026

DNA-Guided CRISPR Technology Enhances Precision and Reduces Off-Target Effects

A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise and more affordable, while opening the door to entirely new ways of controlling disease.

15 May 2026

Epigenetic Engineering Boosts Stable Production of Safe Monascus Pigments

This study was led by Professor Yi Wang and Professor Weiming Zhu from the School of Medicine and Pharmacy, Ocean University of China.

15 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

Novel RNA Analysis Method Supports Antiviral Drug Discovery

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called 'sm-PORE-cupine', to study individual RNA molecules and reveal how their structures influence gene regulation, a fundamental process that affects how cells function in health and disease.

15 May 2026

Most Australian ‘Wild Dogs’ are Predominantly Dingoes

A new genetic test has revealed that most of the free-roaming canines in Australia, often labelled ‘wild dogs’, carry a significant amount of dingo ancestry.

15 May 2026

Scientists Discover How DNA Damage Modulates the Tumor Microenvironment for Therapy

Researchers have identified a pathway that triggers an immune response in cells with defective DNA repair.

14 May 2026

Prime Assembly Enables Precise Insertion of Large DNA Segments Into the Genome

Researchers at UMass Chan Medical School have developed a gene editing technology that allows for the precise and efficient insertion of very large DNA segments into the human genome.

13 May 2026

Inherited Genetic Pathways Shape Individual Cancer Risk and Outcomes

Why do two people with the same cancer diagnosis-the same stage, the same cell type, and the same clinical profile-often have completely different outcomes? For decades, scientists have studied acquired mutations in cancer to find answers, but mutations alone explain only part of the story.

12 May 2026

Genome News and Research

Cornell Researchers Develop Safer CRISPR Technique Using DNA Nicks

Cells Sense Abnormal RNA Patterns to Silence Jumping Genes

Researchers Link Brain Extracellular Matrix Deterioration to Postmenopausal Memory Loss

Dividing Cells Replicate Chromosomal Errors to Trigger Advanced Tumor Progression and Growth

High Protein Levels Bypass Functional BRCA Defenses to Generate Toxic Double-Strand Genomic Breaks

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

New Epigenetic Study Discovers Inheritance Patterns That Defy Mendel's Laws

Protein Plays Dual Role by Silencing Thousands of Genes While Keeping Vital Ones Active

Researchers Reverse Immune Cell Dysfunction by Degrading Key Gene Regulatory Proteins

Cell Study Challenges Long-Standing View That Individual Human Genomes Evolve Independently

Novel Formicitoxins Found in Carpenter Ant Venom Offer Drug Discovery Impetus

Novel Breast Cancer DNA Signatures Reveal Link Between Genomes and Tumor Immunity

DNA-Guided CRISPR Technology Enhances Precision and Reduces Off-Target Effects

Epigenetic Engineering Boosts Stable Production of Safe Monascus Pigments

Animals Adapt Rapidly Through Protein Networks, Not Genes

Novel RNA Analysis Method Supports Antiviral Drug Discovery

Most Australian ‘Wild Dogs’ are Predominantly Dingoes

Scientists Discover How DNA Damage Modulates the Tumor Microenvironment for Therapy

Prime Assembly Enables Precise Insertion of Large DNA Segments Into the Genome

Inherited Genetic Pathways Shape Individual Cancer Risk and Outcomes

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