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Genetic Diversity in Wild Rice Offers Clues for Crop Improvement

A new study, seen in Nature Genetics and led by researchers at King Abdullah University of Science and Technology (KAUST; Saudi Arabia) and Wageningen University & Research (the Netherlands), provides new insights on rice evolution, showing how the DNA of this valuable crop has changed across species.

29 Apr 2025

New Pangenome Analysis Uncovers Genetic Key to Larger Peanut Yields

Researchers from Australia and China have identified crucial structural variations that determine seed size and weight in peanuts, paving the way for the development of higher-yielding crop varieties.

29 Apr 2025

Transitioning Pancreatic Cells Retain Cancer Linked Epigenetic Marks

Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a temporary "memory" of those cancer-linked marks.

25 Apr 2025

Researchers Create DNA Editing Technique to Improve Lactobacillus Strains

A Kobe University team was able to edit the DNA of Lactobacillus strains directly without a template from other organisms.

24 Apr 2025

AI-Powered Protein Engineering for Precise and Scalable Gene Therapy

Genome editing has progressed rapidly, showing promising outcomes for the treatment of genetic disorders, yet there remains potential for enhancement.

23 Apr 2025

Study Reveals Shared Genetic Basis for Autism Spectrum Disorder and DM1

Researchers from the University of Las Vegas Nevada (UNLV) and The Hospital for Sick Children (SickKids) have discovered a genetic connection between autism spectrum disorder (ASD) and myotonic dystrophy type 1 (DM1), a rare genetic disorder.

23 Apr 2025

Guinea Pig Modeling To Study Human Preimplantation and Embryogenesis

Research on guinea pig embryos uncovers similarities to human embryogenesis, advancing understanding of preimplantation stages and reproductive techniques.

23 Apr 2025

DNA Organization Offers Clues for Advancing Stem Cell Therapy

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power. The researchers demonstrate in a paper published in the journal Genes & Development that these cells rely on a group of helper proteins called histone chaperones — organizers or guides known to help package our two-meter-long genome when cells need to divide or switch on specific genes.

22 Apr 2025

Cyber Vulnerabilities in Next-Gen DNA Sequencing

Next-generation DNA sequencing (NGS), a technology driving personalized medicine, cancer diagnosis, infectious disease tracking, and genetic research, is increasingly vulnerable to cyberattacks.

17 Apr 2025

Giant Virus Isolation Underscores the Understudied World of Microbes

Researchers at the Nanoscience Center of the University of Jyväskylä have achieved a first in Finland by isolating a giant virus, which they have named Jyvaskylavirus.

17 Apr 2025

Researchers Develop Quantum-AI Platform to Predict Antimicrobial Resistance in Salmonella

SARPLLM leverages large language modeling and quantum algorithms to predict Salmonella AMR, offering robust analysis and user-friendly data visualization tools.

17 Apr 2025

Tumor Recurrence Prediction from Multi-Omics Information by Deep Learning

MULGONET combines deep learning and multi-omics analysis to predict tumor recurrence, addressing interpretability and enhancing cancer prognosis understanding.

16 Apr 2025

How P. syringae Outsmarts Amoeba with Chemical Surveillance and Strikes

Pseudomonas syringae's chemical sensing system allows it to kill amoeba predators, showcasing its evolutionary strategies for survival and plant infection.

14 Apr 2025

Complete Reference Genomes Unlocked for Six Ape Species

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee.

12 Apr 2025

Researchers Develop STITCHR to Insert Whole Genes Without Unwanted Mutations

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations.

12 Apr 2025

New Genetic Insights From Long Read Sequencing in a Teen With Complex Psychiatric Conditions

In a manuscript published today in the American Journal of Psychiatry titled Long-Read Genome Sequencing in Clinical Psychiatry: RFX3 Haploinsufficiency in a Hospitalized Adolescent With Autism, Intellectual Disability, and Behavioral Decompensation, authors describe how they leveraged long-read genomic sequencing (LRS) to make a genetic diagnosis in a17-year-old male with autism spectrum disorder, intellectual disability, and acute behavioral decompensation that would not have been possible by standard methods.

12 Apr 2025

Genetic Sequencing Leads to Major Discovery in Neurodevelopmental Disorders

A seminal study from researchers at the Icahn School of Medicine at Mount Sinai and their collaborators in the United Kingdom, Belgium, Spain, the Netherlands, and Iceland has uncovered a new genetic cause of neurodevelopmental disorders (NDDs).

11 Apr 2025

Genetic Variants Offer Clues to Targeted Asthma Treatments

Genome wide association studies (GWAS) have identified hundreds of genome regions containing thousands of genetic variants associated with asthma, but it's still not clear which variants have an actual causal link to the disease.

11 Apr 2025

Japanese Researchers Develop New Assay to Detect Epigenetic Toxicity

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard.

11 Apr 2025

Breakthrough Delivery System Advances CRISPR-Based Treatments

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before.

10 Apr 2025