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AlphaSync Brings Continuous Updates to Global Protein Structure Predictions

The shape, or structure, of proteins determines how they work, making it essential for researchers to have access to high-quality structural models.

12 Nov 2025

CellWhisperer Enables Natural Language Exploration of Single-Cell Biology

Using sophisticated RNA sequencing technology, biomedical researchers can measure the activity of our genes across millions of single cells, creating detailed maps of tissues, organs, and diseases.

12 Nov 2025

Scientists Build a Genetic Map to Predict Bacterial Resistance Mechanisms

The bacteria Acinetobacter baumannii (A. baumannii) is a haunting presence in many hospitals in the United States, where more than one in 100 patients are treated for A. baumannii infections.

10 Nov 2025

Human Pangenome Research Opens a New Chapter in Precision Medicine

In May 2023, the Human Pangenome Reference Consortium (HPRC) released the first draft of the human pangenome reference sequence, which integrated genomic data from 47 individuals representing genetic diversity and added 119 million base pairs of euchromatic polymorphic sequences.

10 Nov 2025

Researchers Find "Hidden" Mutations by Tracing Protein Isoforms

Approximately 25 million individuals in the United States are affected by a rare genetic disorder, and a significant number of them face challenges not only due to the absence of effective treatments but also because of insufficient information regarding their condition.

10 Nov 2025

St. Jude Scientists Discover Hidden Binding Pocket in Nuclear Receptors

A study from St. Jude Children's Research Hospital uncovered an alternative binding pocket within nuclear receptors, revealing a much-needed new therapy route for this important class of drug targets.

7 Nov 2025

Comprehensive Kinase Atlas Redefines Regulation of Gene Transcription Machinery

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

New Tool Merges Ex-Vivo and In-Vivo Brain Data for White Matter Research

BraDiPho is an innovative tool for the study of white matter connections in the human brain. A realistic map developed by a group of researchers from the University of Trento, the Provincial Healthcare Service of Trento, Fondazione Bruno Kessler and the Universities of Bordeaux and Sherbrooke.

7 Nov 2025

Hidden Role of Biliverdin Reductase A in Fighting Oxidative Damage

According to a new study from Johns Hopkins Medicine, the enzyme biliverdin reductase A (BVRA) protects neurons directly from oxidative stress, regardless of whether it produces the yellow pigment bilirubin.

5 Nov 2025

Enzyme BVRA Found to Shield Neurons from Oxidative Stress

New research from Johns Hopkins Medicine shows that the enzyme biliverdin reductase A (BVRA) plays a direct protective role against oxidative stress in neurons, independent of its role producing the yellow pigment bilirubin.

4 Nov 2025

New Genomic Method Unlocks Diagnoses for Rare Conditions

A new genomic method has enabled multiple people with rare conditions to receive diagnoses that were previously unattainable by identifying complex structural genetic changes that are often missed by standard tests.

4 Nov 2025

Reactivating a Naturally Occurring Gene Promotes Heart Repair and Regeneration

A naturally occurring gene called Cyclin A2 (CCNA2), which turns off after birth in humans, can actually make new, functioning heart cells and help the heart repair itself from injury including a heart attack or heart failure when the gene is turned back on.

4 Nov 2025