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Clinician-Led Approach Could Give Doctors a Control Dial for Cell Therapies

A clinician-led research team has developed a gene-editing platform that could give doctors more control over cell therapies, making them more practical for patients with complex immune conditions.

20 Oct 2026

Regular Hot Baths Could Alleviate Common Circulatory Disease

A regular soak in a hot bath could help to improve a common painful circulatory disease, with this strategy being studied by researchers at Manchester Metropolitan University, thanks to funding from the British Heart Foundation.

20 Oct 2026

Millions of Older Australians Exposed to Overlapping Medication Risks

An estimated 2.3 million older Australians are being dispensed multiple medicines associated with falls and fractures, while more than 1.2 million are receiving combinations linked to kidney-related side effects, according to new research from Adelaide University.

20 Oct 2026

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Immune checkpoint inhibitors (ICIs) have transformed cancer care, yet only a subset of patients benefit. A major barrier is tumor microenvironment (TME) heterogeneity: "hot" tumors are enriched with cytotoxic T lymphocytes (CTLs) and respond better, while "cold" tumors lack T-cell infiltration or are shielded by immunosuppressive barriers.

20 Oct 2026

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

20 Oct 2026

Food Allergy Risk Changes as Children Grow

Sensitization to food allergens can change considerably during the first five years of a child’s life. A large Canadian birth-cohort study shows that sensitization to peanut often develops early and persists, while sensitization to several tree nuts tends to appear later.

16 Oct 2026

Scientists Discover Molecular Chain Reaction Behind Sound Wave Healing

Researchers from Capital Medical University, Beijing, China, have identified a CaN/NFATC3/Id3/E2A/Bmp4 signaling pathway that helps explain how low-intensity pulsed ultrasound (LIPUS) promotes bone regeneration.

16 Oct 2026

Lipid Nanoparticles Reprogram NK Cells Internally to Eliminate Cancerous T Cells

MIT engineers have developed a new way to program natural killer (NK) immune cells to target cancerous T cells or T cells that have become autoreactive, leading to diseases such as lymphoma and autoimmune hepatitis.

14 Oct 2026

Study Creates Global Single-Cell Map of Human Immune System Aging

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health.

10 Oct 2026

Epigenetic DNA Methylation Clocks Track Gradual Cellular Rejuvenation Across Fifty Days

Researchers from the University Hospital of Bonn and the University of Bonn have succeeded in dramatically rejuvenating human cells in a test tube. To do so, they directly reprogrammed red blood cell precursors into stem cells from which neurons can be derived. During this process, the molecular clocks that indicate a cell's age were reset.

10 Oct 2026

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood. St. Jude Children's Research Hospital scientists and their collaborators built one of the most comprehensive datasets of neuroblastoma cells to date, using it to define the tumor's cell types and identify a gene signature marking a malignant cell population tied to poor prognosis.

10 Oct 2026

Proteomic Profiling Uncovers Twenty-Four Plasma Proteins Tied to Gut Mucosal Inflammation

Coeliac disease is an autoimmune condition in which the immune system reacts adversely to gluten. Eating gluten causes inflammation in the gut, which can damage the intestine and impair its ability to absorb nutrients.

10 Oct 2026

Females with Autoimmune Diseases ‘Less Likely to be Believed’ Than Males and Face Longer Diagnostic Delays

Females with autoimmune diseases are significantly more likely than males to have their autoimmune disease misdiagnosed as a psychiatric or psychosomatic condition, according to a study of more than 6,600 patients.

9 Oct 2026

Studies Redefine Lactation Biology Through Computational Multi-Omics and Mammary Metabolic Modeling

A study led by researchers at NYU Grossman School of Medicine identified shared molecular patterns in human milk that link maternal nutrition, mammary gland biology, and infant growth.

9 Oct 2026

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease.

8 Oct 2026

Targeting Host Cellular Repair Mechanisms Enhances Tissue Resistance to Infection

Epithelial cells form the body's frontline barriers, helping keep microbes, toxins, and other harmful substances out. Yet these protective cells are constantly exposed to threats, including microbial infections.

6 Oct 2026

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of the Division of Medical Oncology/Hematology at Kobe University Hospital, together with Associate Professor Goh Ohji of the Division of Infectious Disease Therapeutics and Takaji Matsutani of Anymics Inc., has developed the pGen-SHM plot.

5 Oct 2026

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it. These are the key findings from a joint German-Austrian study led by the University of Bonn, details of which have now been published in the journal "Nature Metabolism."

1 Oct 2026

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Mount Sinai researchers have identified how APOE4, the strongest genetic risk factor for Alzheimer's disease, damages the brain's blood vessels and promotes the buildup of abnormal proteins linked to neurodegenerative disease.

26 Sep 2026

Chronic Inflammation Linked to Heart Changes and Risks

Chronic inflammation, indicated by GlycA levels, has been linked to heart changes and increased cardiovascular risk, highlighting genetic and environmental interactions.

25 Sep 2026

Hospital News and Research

Clinician-Led Approach Could Give Doctors a Control Dial for Cell Therapies

Regular Hot Baths Could Alleviate Common Circulatory Disease

Millions of Older Australians Exposed to Overlapping Medication Risks

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Food Allergy Risk Changes as Children Grow

Scientists Discover Molecular Chain Reaction Behind Sound Wave Healing

Lipid Nanoparticles Reprogram NK Cells Internally to Eliminate Cancerous T Cells

Study Creates Global Single-Cell Map of Human Immune System Aging

Epigenetic DNA Methylation Clocks Track Gradual Cellular Rejuvenation Across Fifty Days

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Proteomic Profiling Uncovers Twenty-Four Plasma Proteins Tied to Gut Mucosal Inflammation

Females with Autoimmune Diseases ‘Less Likely to be Believed’ Than Males and Face Longer Diagnostic Delays

Studies Redefine Lactation Biology Through Computational Multi-Omics and Mammary Metabolic Modeling

Stem Cell Models Demonstrate Precise Cellular Nibbling of Pathological Fibrils

Targeting Host Cellular Repair Mechanisms Enhances Tissue Resistance to Infection

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

Kupffer Cells Increase Apolipoprotein Secretion in Response to Indigestible Plastics

Engineered 3D miBrains Model Human Neurovascular Units and Pathology

Chronic Inflammation Linked to Heart Changes and Risks

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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