Immune Response News and Research

RSS

AI Predicts Viral Mutations to Design Future-Proof Vaccines

The wave-shaped chart Ratul Chowdhury pulls up on a computer monitor in his office captures the evolutionary cat-and-mouse game his research lab is up against.

13 Apr 2026

Nanodisc Platform Shows How Antibodies Really Target Viruses

Viruses are masters at entering human cells, thanks to specialized proteins that coat their surfaces.

13 Apr 2026

UTMB Researchers Develop AI Pipeline to Accelerate Pan-Alphavirus Vaccine Development

A team of scientists at The University of Texas Medical Branch (UTMB), led by Nikos Vasilakis, PhD, and Peter McCaffrey, MD, has developed a new computational pipeline that could dramatically accelerate the development of vaccines against a group of mosquito-borne viruses known as alphavirus.

11 Apr 2026

Novel ENDOtollins Block Harmful Inflammation While Preserving Infection Response

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

7 Apr 2026

Tumors Disable Dendritic Cells by Decreasing Mitochondrial Fitness

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy.

3 Apr 2026

Discovery Challenges the Theory That Proteins Move Mainly by Diffusion

Scientists at Oregon Health & Science University have uncovered a previously unknown system of internal "trade winds" that help cells rapidly move essential proteins to the front of the cell, reshaping how researchers understand cell migration, cancer spread and wound healing.

31 Mar 2026

Novel Immunotherapy Disrupts the Protective Tumor Microenvironment Ecosystem

Chimeric antigen receptor T-cell therapy - CAR T for short - has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two main reasons: tumor cells often don't share one consistent surface target, and many solid tumors are protected by a dense network of scar tissue and immune-suppressive cells that blocks T cells.

31 Mar 2026

New Technology Enables Whole-Body Analysis of Gene Expression

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of tissue.

30 Mar 2026

Study Reveals How STING Protein Migrates to Trigger Immune Responses

UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of interferon genes (STING) migrates from one cellular organelle to another, a necessary step in its activation.

27 Mar 2026

Researchers Identify the Nuclear Root of Cellular Aging

Some aging indications in human cells arise in the cell nucleus, where the packaged form of DNA changes with age.

27 Mar 2026

Mice Study Reveals Cholecystokinin as Key Driver of Obesity-Related Pancreatic Cancer

Obesity increases the body's need for insulin, forcing cells in the pancreas known as beta cells to ramp up insulin production to maintain blood sugar levels.

22 Mar 2026

Psoriasis-Like Inflammation Limits Skin Cancer Growth

A study shows that psoriasis-like immune responses may limit skin cancer growth, challenging the view of chronic inflammation as solely tumor-promoting.

19 Mar 2026

New Ring Structure Guides Precise Cell Death and Immunity

Researchers at the University of Michigan have revealed that cells use a previously unknown feat of molecular craftsmanship to help protect their larger host organisms.

16 Mar 2026

Study Reveals How Altering Cancer’s Protein Machinery Stimulates Antitumor Immunity

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly disrupting the way tumors produce their proteins can trigger a potent antitumor immune response.

12 Mar 2026

Study Uncovers Regulated Nuclear DNA Extraction in Dying Cells

Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is separated from the cytoplasm by a robust nuclear envelope.

26 Feb 2026

New Gene-Editing Strategy to Eliminate Aggressive Cancer Cells

The initiation and severity of cancer are associated with the atypical behavior of specific genes, referred to as oncogenes. The most recognized of these changes is mutation; however, it is not the sole alteration.

9 Feb 2026

DNA Origami Vaccine Scaffolds Sharpen Immune Targeting Against HIV

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus.

6 Feb 2026

Chemistry Breakthrough Improves Gene Delivery, Reduces Side Effects

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

5 Feb 2026

How DNA Leakage into the Cytoplasm Drives Ruijs-Aalfs Syndrome

Although DNA is tightly packed and safeguarded within the cell nucleus, it remains continually at risk of damage from normal metabolic activity and external stressors such as radiation and chemical agents.

2 Feb 2026

Gut Microbial Metabolite Hippuric Acid Amplifies Immune Responses

Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from berries, tea, and other plant-based foods.

31 Jan 2026