Immunotherapy News and Research

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Immunotherapy is the concept of using the immune system to treat disease, for example, developing a vaccine against cancer. Immunotherapy may also refer to the therapy of diseases caused by the immune system, allergies for example.

Wireless Electric Fields Guide Immune Cells But Disorient Cancer Cells

Traditional electrotaxis assays place electrodes directly into the cell culture medium, which inevitably drives current through the sample.

27 May 2026

Macrophage Placement Determines if Tumors Thrive or Regress

Cancer tumors are surrounded by immune cells, but not all of those cells help the body fight back. Some support anti-cancer immunity, while others can unexpectedly help tumors survive.

27 May 2026

Aggressive Breast Cancer Cells Lose Spatial Persistence When Exposed to Wireless Electric Fields

Traditional electrotaxis assays place electrodes directly into the cell culture medium, which inevitably drives current through the sample.

26 May 2026

Genomewide CRISPR Screen Reveals Unexpected Structural Protein Link Behind Chronic Colon Inflammation

Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor formation, potentially leading to colorectal cancer, by secreting a toxin that damages the lining of the colon. But until now, the exact mechanism the toxin uses to latch onto those cells remained a mystery.

25 May 2026

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

Scientists at the Garvan Institute of Medical Research have captured, for the first time, 'housekeeping' immune cells actively attacking and engulfing live melanoma cells – a discovery that could change the way we approach treatment for one of Australia's most common and deadly cancers.

22 May 2026

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

Researchers with the James P. Allison Institute™ at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.

21 May 2026

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve responses to immunotherapy.

20 May 2026

Scientists Design Decoy Peptides to Prevent Chronic Overactivation of Immune Cells

Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important cellular messengers.

19 May 2026

Low-Oxygen Environments Enhance Engraftment and Function of Transplanted Stem Cells

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have found that human hematopoietic stem cells are highly sensitive to oxygen, which can dictate how the cells grow and function.

19 May 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

MD Anderson Researchers Map DNA Replication Stress at Single-Cell Resolution

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution.

28 Apr 2026

New Method Predicts Cancer Patient Outcomes at Single-Cell Resolution

Oregon Health & Science University researchers have developed a first-of-its-kind method to predict cancer patient survival using advanced molecular data from individual cells.

22 Apr 2026

Scientists Map Human Genes That Control HIV Infection Dynamics

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body.

21 Apr 2026

New Data Demonstrates the Unique Scalability of Evaxion’s AI-Immunology™ Platform in Glioblastoma

Evaxion A/S (“Evaxion”), a clinical-stage TechBio company developing novel vaccines with its pioneering AI-Immunology™ platform, announces new data demonstrating the platform’s ability to also potentially develop vaccines for glioblastoma (brain cancer).

From Evaxion A/S 21 Apr 2026

Scientists Uncover the Molecular Fingerprints of mRNA Vaccine-Induced T Cells

The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the Nobel-prize–winning technology is being adapted to fight cancer, with mRNA vaccines in clinical trials for melanoma, small cell lung cancer and bladder cancer, among others, opening the door to new ways of preventing and treating the disease.

17 Apr 2026

CIPHER-seq Reveals RNA and Protein Activity in Immune Cells

A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic intent but real-time activity.

9 Apr 2026

Tumors Disable Dendritic Cells by Decreasing Mitochondrial Fitness

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring their energy production can improve immunotherapy.

3 Apr 2026

Defining Tumor Microbiota for Improved Cancer Diagnosis and Treatment

Recent research shows that tumors in different organs host microbial communities capable of influencing cancer biology, immune responses, and the effectiveness of therapies, highlighting the need to standardize methods for studying intratumoral microbes.

3 Apr 2026

Cysteine Pathways Shape T Cell Expansion and Cancer Defense

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health have discovered how the immune system's CD8+ T cells use the nutrient cysteine to control two essential functions that compete for this resource - the immune cell's ability to multiply and its ability to kill cancer cells.

1 Apr 2026

Immunotherapy News and Research

Wireless Electric Fields Guide Immune Cells But Disorient Cancer Cells

Macrophage Placement Determines if Tumors Thrive or Regress

Aggressive Breast Cancer Cells Lose Spatial Persistence When Exposed to Wireless Electric Fields

Genomewide CRISPR Screen Reveals Unexpected Structural Protein Link Behind Chronic Colon Inflammation

Scientists Capture Live-Action Footage of Housekeeping Immune Cells Engulfing Melanoma

Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Scientists Design Decoy Peptides to Prevent Chronic Overactivation of Immune Cells

Low-Oxygen Environments Enhance Engraftment and Function of Transplanted Stem Cells

How the Microbiome Shapes Cancer Immunity and Therapy Response

MD Anderson Researchers Map DNA Replication Stress at Single-Cell Resolution

New Method Predicts Cancer Patient Outcomes at Single-Cell Resolution

Scientists Map Human Genes That Control HIV Infection Dynamics

New Data Demonstrates the Unique Scalability of Evaxion’s AI-Immunology™ Platform in Glioblastoma

Scientists Uncover the Molecular Fingerprints of mRNA Vaccine-Induced T Cells

CIPHER-seq Reveals RNA and Protein Activity in Immune Cells

Tumors Disable Dendritic Cells by Decreasing Mitochondrial Fitness

Defining Tumor Microbiota for Improved Cancer Diagnosis and Treatment

Cysteine Pathways Shape T Cell Expansion and Cancer Defense

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