Inflammation News and Research

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New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

28bio today announced CNS-3D Inflammatory Organoids, designed to evaluate efficacy of anti-inflammatory drugs by quantifying their ability to reduce inflammatory injury, preserve tissue health, and restore neuronal network activity.

20 May 2026

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Researchers developed a 3D liver model that functions for a month, replicating inflammation and fibrosis, crucial for studying liver diseases and therapies.

19 May 2026

Advanced Genomic Techniques Map Cellular Changes During Brain Aging

While much is mysterious about the aging process, change over time remains its cornerstone. The biological shifts that accompany aging seemingly occur in many cells in the body.

18 May 2026

Selective Elimination of Harmful Senescent Cells Supports Healthy Aging

A new review was published in Volume 18 of Aging-US on May 4, 2026, titled "Cellular senescence: from pathogenic mechanisms to precision anti-aging interventions."

15 May 2026

Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly used therapies.

14 May 2026

Cryo-EM Study Explains Why Coffee Tastes Bitter to Humans

Have you ever wondered why freshly brewed coffee smells so delicious, but tastes bitter?

12 May 2026

Mechano-Chemo-Biological Coupling May Explain Complex Tissue Behaviors

Modern biology can now image forces, structures, and signals with remarkable precision, yet explaining how they work together remains difficult.

11 May 2026

Why Women Face a Much Higher Risk of Autoimmune Disease

A recent study has identified biological abnormalities that make the female immune system more likely to mistakenly attack the body's own healthy tissues, providing insight into why women are significantly more likely than men to experience autoimmune diseases.

8 May 2026

Cell Swelling Found to Trigger Inflammatory Immune Responses

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune system.

8 May 2026

AI Designs New Antibiotics That Reduce MRSA Infections In Mice

SyntheMol-RL integrates reinforcement learning for antibiotic design, producing synthesizable candidates that show efficacy against MRSA in preclinical models.

5 May 2026

Stage-Dependent Gene Expression Changes Reveal Cellular Aging Dynamics

A new research paper was published in Volume 18 of Aging-US on April 10, 2026, titled "Stage-dependent transcriptomic changes in human dermal fibroblast senescence model."

30 Apr 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

MD Anderson Researchers Map DNA Replication Stress at Single-Cell Resolution

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution.

28 Apr 2026

Obesity Leaves Persistent Epigenetic Marks on Immune Cells

People who live with obesity are 'tagging' a memory of being overweight on a key part of the immune system - leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10 year-long study published in EMBO Reports.

28 Apr 2026

Influenza D Virus Shows Potential to Infect Human Cells

The influenza D virus that researchers say has been flying under the radar since its detection in animals in 2011 can vigorously make copies of itself in human cells and lung tissue samples, a new study shows.

27 Apr 2026

Discovery of Heme Transport Pathway Solves Longstanding Red Blood Cell Enigma

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry oxygen to tissues, even after shedding the vital structures they need to produce it.

25 Apr 2026

New Genetic Pathways Linked to Cardiometabolic Disease Identified

A study published today in PLOS Medicine has identified two new genetic pathways that contribute to cardiometabolic disease, which includes heart disease, obesity and diabetes.

24 Apr 2026

New Study Uncovers Previously Undetected Form of DNA Damage

In everyday life, our genetic material is constantly under attack from many factors. Environmental influences such as light, along with internal processes like inflammation, can generate oxidative stress that damages DNA and its downstream partner, RNA, which can lead to faster aging and diseases such as cancer.

24 Apr 2026

Genetic Study Reveals Biological Drivers of Frailty in Aging

Researchers at McMaster University have identified, for the first time, a novel region of DNA and two associated genes connected to frailty, offering neurological and immune-related insights that might help explain why some older adults are more likely to be frail than others.

22 Apr 2026

Molecular Keyhole Discovery Unlocks New Target for Pain Therapies

Researchers at VIB, VUB, and KU Leuven have identified a tiny binding site, a molecular 'keyhole', in the TRPM3 ion channel, a crucial sensor in pain signaling.

22 Apr 2026