Inflammation News and Research

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Inflammatory Cytokines Trigger Higher Protein Levels as a Natural Defense Mechanism Against Disease

A new study from researchers at the University of Chicago provides important insight into how the pancreas protects itself during inflammation, pointing to promising new directions for treating pancreatitis.

23 May 2026

Study Explains Why Persistent Gut Damage Continues Despite HIV Treatments

For many people living with HIV, today's treatments can suppress the virus and dramatically improve health. But even when HIV is controlled, damage to the gut caused by the disease can persist, fueling chronic inflammation linked to serious health problems. A new Tulane University study published in JCI Insight helps explains why.

23 May 2026

Scientists Find Key Genetic Boundary That Dictates Immune System Failure

Not all broken genes fail in the same way: some simply stop working, while others interfere with what still works.

22 May 2026

Researchers Discover That Lesion Cells Fail to Recruit Surrounding Tissue Into Tumor Growth Helpers

In an unexpected finding, a new study flips on its head researchers' understanding of how precancerous pancreas lesions evolve into pancreatic cancer. The paradigm-changing discovery has tremendous implications for identifying people at higher risk of cancer or even, potentially stopping malignant transformation.

21 May 2026

Polymer Platforms Help Focus Immune Attack on Cancerous Tumors

Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less than 30% of patients.

21 May 2026

New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

28bio today announced CNS-3D Inflammatory Organoids, designed to evaluate efficacy of anti-inflammatory drugs by quantifying their ability to reduce inflammatory injury, preserve tissue health, and restore neuronal network activity.

20 May 2026

New 3D Human Liver Model Mimics Chronic Disease For 30 Days

Researchers developed a 3D liver model that functions for a month, replicating inflammation and fibrosis, crucial for studying liver diseases and therapies.

19 May 2026

Advanced Genomic Techniques Map Cellular Changes During Brain Aging

While much is mysterious about the aging process, change over time remains its cornerstone. The biological shifts that accompany aging seemingly occur in many cells in the body.

18 May 2026

Selective Elimination of Harmful Senescent Cells Supports Healthy Aging

A new review was published in Volume 18 of Aging-US on May 4, 2026, titled "Cellular senescence: from pathogenic mechanisms to precision anti-aging interventions."

15 May 2026

Study Reveals New Biological Pathway for TNF-Resistant Crohn’s Disease

Mayo Clinic researchers have identified an immune-regulating molecule that may help explain why some patients with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, do not respond to commonly used therapies.

14 May 2026

Cryo-EM Study Explains Why Coffee Tastes Bitter to Humans

Have you ever wondered why freshly brewed coffee smells so delicious, but tastes bitter?

12 May 2026

Mechano-Chemo-Biological Coupling May Explain Complex Tissue Behaviors

Modern biology can now image forces, structures, and signals with remarkable precision, yet explaining how they work together remains difficult.

11 May 2026

Why Women Face a Much Higher Risk of Autoimmune Disease

A recent study has identified biological abnormalities that make the female immune system more likely to mistakenly attack the body's own healthy tissues, providing insight into why women are significantly more likely than men to experience autoimmune diseases.

8 May 2026

Cell Swelling Found to Trigger Inflammatory Immune Responses

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune system.

8 May 2026

AI Designs New Antibiotics That Reduce MRSA Infections In Mice

SyntheMol-RL integrates reinforcement learning for antibiotic design, producing synthesizable candidates that show efficacy against MRSA in preclinical models.

5 May 2026

Stage-Dependent Gene Expression Changes Reveal Cellular Aging Dynamics

A new research paper was published in Volume 18 of Aging-US on April 10, 2026, titled "Stage-dependent transcriptomic changes in human dermal fibroblast senescence model."

30 Apr 2026

How the Microbiome Shapes Cancer Immunity and Therapy Response

This review examines how the human microbiome regulates anti-tumor immunity through DNA damage, inflammation, immune-cell activity, microbial metabolites, and tumor microenvironment remodeling. It highlights emerging microbiome-based strategies, including FMT, probiotics, prebiotics, engineered bacteria, and live biotherapeutics, while stressing the need for rigorous validation and clinical trials.

29 Apr 2026

MD Anderson Researchers Map DNA Replication Stress at Single-Cell Resolution

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with single-cell resolution.

28 Apr 2026

Obesity Leaves Persistent Epigenetic Marks on Immune Cells

People who live with obesity are 'tagging' a memory of being overweight on a key part of the immune system - leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10 year-long study published in EMBO Reports.

28 Apr 2026

Influenza D Virus Shows Potential to Infect Human Cells

The influenza D virus that researchers say has been flying under the radar since its detection in animals in 2011 can vigorously make copies of itself in human cells and lung tissue samples, a new study shows.

27 Apr 2026