Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Bio‑Techne and Refeyn Close Critical Gap in Bispecific Antibody and Biosimilar Characterization

Bio‑Techne Corporation, a global provider of life science tools, reagents and diagnostic products, and Refeyn, the pioneer in mass photometry technology, today announced a first‑of‑its‑kind integrated workflow for the characterization of charge and size variants in bispecific antibodies and biosimilars.

From Bio-Techne 4 Jun 2026

Study Shows How AI and Single Cell Science are Changing Modern Medicine

Recent technological advances have pushed the boundaries of cellular biology far beyond what was conceivable even decades ago

4 Jun 2026

How Tiny Molecular Tethers Prevent Plant Cells From Crumpling

Water deficit resistance in plants has long been a topic of interest for cultivating reliable crops.

3 Jun 2026

Introducing Evosep Proteomics to Standardize and Scale Proteomics for Research and Drug Development

Evosep announces the launch of Evosep Proteomics, an ecosystem designed to standardize and scale LC-MS-based proteomics for research and pharmaceutical drug development.

From Evosep 2 Jun 2026

New TriPcide Antibiotics Kill Dormant MRSA Without Resistance

The study on TriPcides reveals their ability to combat MRSA and dormant bacteria, offering a new strategy to address antimicrobial resistance in public health.

27 May 2026

Ovarian Cancer Fluid Helps Tumors Evade Cell Death

Ascites in ovarian cancer rewires tumor metabolism, protecting cells from ferroptosis and promoting metastasis, revealing potential therapeutic targets.

27 May 2026

Synthetic Biology and Artificial Intelligence Transform the Discovery of Mysterious Orphan Receptors

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping

23 May 2026

Can Everyday Supplements Lead to Failed Anti-Doping Tests?

Researchers developed a high-throughput LC-MS/MS platform that screened 331 pharmacologically active compounds and quantitatively validated 214 analytes across representative food matrices. Applied to 78 commercial foods and supplements, the framework showed that some products could produce modeled urinary concentrations exceeding WADA reporting thresholds under realistic intake scenarios.

19 May 2026

Epigenetic Engineering Boosts Stable Production of Safe Monascus Pigments

This study was led by Professor Yi Wang and Professor Weiming Zhu from the School of Medicine and Pharmacy, Ocean University of China.

15 May 2026

Web-Based Platform Facilitates Chemical Structure Queries in Metabolomics

An international team led by researchers at University of California San Diego and University of California, Riverside has developed a free, web‑based platform designed to make public metabolomics data more accessible.

15 May 2026

New Single-Cell Technique Reveals Why Bacteria Survive Antibiotics

SinBactM's innovative approach to single-bacterium metabolomics reveals distinct metabolic states, enhancing understanding of antibiotic resistance in bacteria.

6 May 2026

High Resolution Images Reveal DNA Repair Process in Key Protein

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers.

28 Apr 2026

Advances in Proteomics Accelerate Precision Oncology and Biomarker Discovery

A recent review shows that proteomics-driven multi-omics integration reveals tumor heterogeneity and functional regulatory networks beyond genomic information, facilitating the discovery of clinically relevant biomarkers and therapeutic targets.

28 Apr 2026

New Study Uncovers Previously Undetected Form of DNA Damage

In everyday life, our genetic material is constantly under attack from many factors. Environmental influences such as light, along with internal processes like inflammation, can generate oxidative stress that damages DNA and its downstream partner, RNA, which can lead to faster aging and diseases such as cancer.

24 Apr 2026

Uncovering a Second Pathway for On-Demand Glycogen Regulation

Researchers at WEHI have uncovered a never-before-seen mechanism that human bodies utilize to control sugar. These discoveries redefine basic biological principles and pave the way for new scientific discoveries.

24 Apr 2026

Protein Shape Changes Come Into Focus With LiP-MS and 3D Proteomics

This review explains how LiP-MS detects protein structural changes across whole proteomes, adding functional insight that standard abundance-based proteomics often misses. It also surveys method variants and shows how LiP-MS supports drug-target discovery, disease biomarker research, and the broader framework of “3D proteomics.”

20 Apr 2026

Next-Generation Mass Spectrometry Reveals How DIA Deepens Proteome Coverage

A multivendor comparison in a neonatal mouse model of bronchopulmonary dysplasia found that DIA, especially on next-generation platforms such as Orbitrap Astral and timsTOF Ultra, greatly expanded peptide and protein detection while preserving broad biological concordance. The deeper coverage improved subcellular and pathway annotation, increased differential protein detection, and reduced estimated sample-size needs, although platform-specific technical differences still complicated direct comparisons.

19 Apr 2026

How Single-Cell Proteomics Could Unlock the Rules That Govern Cells

This review shows how single-cell proteomics by mass spectrometry has advanced from an uncertain idea to a rapidly improving toolkit that can now quantify thousands of protein groups from individual cells. It argues that direct protein measurements, combined with better sample preparation, instrumentation, and multiplexing, could help researchers build more mechanistic models of cell biology while pushing throughput far higher.

13 Apr 2026