Metabolites News and Research

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Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025

Built Oral Biofilm Models Reveal How Peri-Implantitis Develops

The study establishes in vitro biofilm models, revealing key insights into dysbiosis in peri-implantitis and paving the way for diagnostic advancements.

12 Sep 2025

Stress Reshapes Brain Cells and Alters Activity in Mice

Canadian researchers show that stress modifies the morphology of brain cells in mice, directly influencing the rodents' level of physical activity.

5 Sep 2025

Targeting the Oral Metagenome to Boost Healthy Bacteria

Professor Zhang, a chemical and biomolecular engineering professor at UC Berkeley, is working to distinguish between the healthy and unhealthy bacteria in the human mouth. Her goal is to promote a probiotic oral microbiome by increasing the population of beneficial bacteria.

5 Sep 2025

How Defined Microbes Decide Chocolate Flavor

This study links microbial activity and fermentation conditions to cocoa flavor profiles, advancing techniques for producing premium chocolate consistently.

27 Aug 2025

Breakthrough Technique Enables Large-Scale Study of Polar and Ionic Metabolites

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Computational Modeling Creates a Database for Improved Detection of Designer Drugs

How do you identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade law enforcement.

21 Aug 2025

New Molecules from the McMaster Greenhouse Target Drug-Resistant Fungi

A research team at McMaster University has discovered a new drug class that could someday lead to breakthrough treatments for dangerous fungal infections.

13 Aug 2025

Multi-Omics Approaches Reveal New Insights into Colorectal Cancer Liver Metastasis

Colorectal cancer is among the most prevalent and lethal malignancies worldwide, with liver metastases occurring in nearly one-third of patients and accounting for a major share of cancer-related deaths.

29 Jul 2025

New Metabolic Map Reveals How Blood Stem Cells Age and Become Diseased

Researchers from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and ETH Zürich have created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize, or turn cancerous.

16 Jul 2025

Exercise Boosts Immune Response in Cancer Through Bacterial Metabolites

A new study from the University of Pittsburgh shows for the first time how exercise improves cancer outcomes and enhances response to immunotherapy in mice by reshaping the gut microbiome.

10 Jul 2025

Mediterranean Bacteria Offer New Weapon Against Mosquito-Borne Diseases

Mosquito-borne diseases kill more than 700,000 people every year, according to the World Health Organization, and the mosquitos that spread the disease are difficult to control.

8 Jul 2025

New AI Tool Illuminates Bacterial Impact on Body Chemistry

Gut bacteria are well-known for playing an important role in a variety of health issues. However, their quantity and variety are immense, as are the ways in which they interact with the body’s chemistry and with one another.

7 Jul 2025

New Study Maps How Pesticides Alter Human Gut Bacteria

While emerging evidence suggests pesticides can be toxic to the mix of microorganisms in the digestive system, a new study is the first to map changes to specific gut bacteria based on interactions between human microbes and insect-killing chemicals observed in the lab and an animal model.

30 Jun 2025