Metabolites News and Research

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Theobromine in Dark Chocolate may Slow Biological Aging

A chemical found in dark chocolate could slow the rate of biological aging.

11 Dec 2025

Nearly 1/3 of Pesticides and Industrial Chemicals Harm Gut Bacteria

A study reveals that common pesticides and industrial chemicals inhibit gut bacteria, highlighting risks to health and the need for revised safety assessments.

5 Dec 2025

Engineered Gut Bacteria With MiRNA Nanoparticles To Reverse IBD

Biomimetic nanoparticles delivering microRNA to gut bacteria enhance protective metabolites, repair intestinal barriers, and alleviate colitis symptoms.

3 Dec 2025

Ambiguous Stop Codons Expand the Genetic Code in Archaea

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in a gene codes for a unique amino acid that's added to a chain of amino acids to make a protein.

2 Dec 2025

Bacteriophages Facilitate the Survival of Lactic Acid Bacteria in Kimchi Fermentation

The World Institute of Kimchi (President: Hae Choon Chang), a government-funded research institute under the Ministry of Science and ICT, has confirmed in a new study that bacteriophages, which were previously considered a 'nuisance' during the process of food fermentation, actually play the role of key helpers that facilitate the survival of lactic acid bacteria (LAB).

21 Nov 2025

Transcription Factor SmMYB53 Drives Enhanced Tanshinone Synthesis in Salvia miltiorrhiza

Salvia miltiorrhiza has long been used in traditional medicine, with tanshinones being its main active compounds.

19 Nov 2025

Scientists Reveal Nonenzymatic Role of NUDT5 in Purine Pathway Regulation

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.

7 Nov 2025

How Gut Bacteria Influence Mammalian Cell Physiology

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital functions.

30 Oct 2025

Rhizosphere Metabolites Play Key Role in Regulating the Distribution of Antibiotic Resistance Genes

Their study reveals that rhizosphere metabolites-substances secreted by plant roots-play a crucial role in regulating the distribution of manure-derived ARGs in both the soil and plant tissues.

27 Oct 2025

First Chromosome-Scale Genome Assembly of Blackcurrant Reveals Drought Adaptation Strategies

Drought stress disrupts plant growth, metabolism, and reproduction, with devastating effects on crop productivity worldwide.

27 Oct 2025

Synthetic Biology Unlocks New Ways to Engineer Plant–Microbe Interactions

By integrating engineering principles with plant biology, this review highlights how redesigned genetic pathways and plant-based biosensors can deepen understanding of plant responses to both harmful and beneficial microbes.

17 Oct 2025

Acidic Tumor Environment Found to Rewire Cancer Cell Metabolism

Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

10 Oct 2025

Studies Uncover PAR2 Receptor’s Role in Gut Inflammation and Pain

Abdominal pain is common in a variety of digestive diseases, including inflammatory bowel disease and irritable bowel syndrome.

8 Oct 2025

New Genetic Map of Human Metabolism Reveals How Genes Influence Health and Disease

A recent study published in Nature Genetics developed the largest genetic map of human metabolism, giving new insights into the role of metabolites in health and disease and providing a framework for future research.

6 Oct 2025

Koala Retrovirus Load Stays Stable And Signals Higher Risk Of Chlamydia Infection

Findings show high koala retrovirus loads correlate with Chlamydia pecorum infection, emphasizing the need for further research on viral-host interactions.

1 Oct 2025

Deciphering the Genetic Logic of Terpene Diversity in Plants

Angiosperms, representing nearly 90% of all plant species, dominate terrestrial ecosystems thanks in part to their sophisticated chemical communication systems.

22 Sep 2025

Metabolic Signals Shape the Rhythm of Embryonic Segmentation

Pregnant women rely on a balanced diet and supplements to deliver proper nutrients to their babies, to ensure they grow healthfully.

22 Sep 2025

Carbon Starvation Drives Metabolic and Epigenetic Reprogramming in Grapevine Cells

Plants rely on sugars not only as energy sources but also as regulators of cellular activities. Carbon starvation disrupts central metabolism, impairs growth, and forces cells to recycle stored resources.

18 Sep 2025

Microbial Molecule Controls Cancer Progression and Boosts Chemotherapy

An international team of scientists led by researchers from the MRC Laboratory of Medical Sciences (LMS), Imperial College London, and the University of Cologne discovered that microbes associated with tumors produce a molecule that can control cancer progression and improve chemotherapy efficacy.

15 Sep 2025

Built Oral Biofilm Models Reveal How Peri-Implantitis Develops

The study establishes in vitro biofilm models, revealing key insights into dysbiosis in peri-implantitis and paving the way for diagnostic advancements.

12 Sep 2025