Molecule News and Research

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Electro-bioprinting as a Tool to Study Early Human Embryonic Development

Bioprinted epiblast-like structures mimic early human embryonic development, offering a scalable, ethical platform to study gastrulation and tissue formation.

11 Jun 2025

Cryo-EM Structures Reveal How IVD Mutations Cause Isovaleric Acidemia

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

10 Jun 2025

New Study Reveals Itaconate’s Crucial Functions in Plants

Zhang, T., et al. (2025) The metabolite itaconate is a transcriptional and posttranslational modulator of plant metabolism, development, and stress response. Science Advances. doi.org/10.1126/sciadv.adt7463.

9 Jun 2025

Novel Peptide Shows Promise in Fighting Deadly, Drug-Resistant Bacteria

A study identifies a new antimicrobial peptide that effectively targets gram-negative bacteria, highlighting its potential in combating antibiotic resistance.

5 Jun 2025

New Technique Harnesses Light to Control Bacteria Without Genetic Modification

A groundbreaking technique developed by Politecnico di Milano researchers is enabling scientists to control specific bacterial functions using light-sensitive materials.

4 Jun 2025

New Insights into the Molecular Fight or Flight Reset

Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allows the body to react swiftly to stress or starvation.

30 May 2025

New Research Reveals Yeast-Based Production of Human DNase1 Protein

Research on yeast-based production of human DNase1 offers a cost-effective alternative to mammalian cells, enhancing treatment options for cystic fibrosis.

29 May 2025

Exploring the Flexible Structure of Sulfite Reductase Enzyme

Visualization of sulfite reductase's structure offers insights into sulfur chemistry, aiding in drug development and understanding bacterial energy sources.

28 May 2025

Peptide Metabolites: A New Frontier in Antiviral Therapies

Interest in antiviral treatments has grown significantly since the COVID-19 pandemic. Effective peptide treatments made from natural substances are in high demand right now due to the increased attention being paid to peptide-based drugs like Wegovy.

27 May 2025

Universal Rules to Guide the Design of Optimal Enzymes

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists from the Max Planck Institute for Dynamics and Self-Organization (MPI-DS) now derived universal rules to enable the de novo design of optimal enzymes.

26 May 2025

Study Shows How Age-Related Metabolic Decline Impairs the Efficacy of CAR-T Cell Therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

26 May 2025

Study Reveals How Genetic Differences in TRIO Affect Neurodevelopment

Researchers have identified how variations in a gene called TRIO can influence brain functions and result in distinct neurodevelopmental diseases.

24 May 2025

New LLNL Method Accelerates Protein Screening for Drug Discovery

Machine learning and supercomputing have brought about a revolution in computational drug discovery.

24 May 2025

Waters Acquires Halo Labs, Expanding Biological Analysis Portfolio

Waters Corporation today announced that it has acquired Halo Labs™, an innovator of specialized imaging technologies to detect, identify, and count interfering materials (particles) in therapeutic products, such as cell, protein, and gene therapies.

23 May 2025

Scientists Develop Method to Overcome Key Limitations of Cryo-EM

Sample loss has been a persistent problem in cryo-EM, a high-tech method for creating 3D models of molecules that reveals their inner structures.

22 May 2025

New CRISPR Technology for Precise RNA Delivery in Neurons

Proteins produced by RNA segments can aid in the repair of damaged neurons in human bodies.

22 May 2025

New Discovery Explains Increased Infection Risk in Patients with Mitochondrial Diseases

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological problems and heart conditions.

21 May 2025

Autophagy: A Double-Edged Sword in Cancer and Protein Conformational Disorders

A new FEBS Letters review explores the dual role of autophagy in cancer and protein misfolding diseases—highlighting its potential as a therapeutic target and the challenges of tipping the balance between protection and harm.

20 May 2025

Novel Bacterial Immune Weapon that Starves Viral Invaders

The discovery of Cat1 reveals how CARF effectors use complex structures to inhibit viral replication, advancing our understanding of bacterial immune responses.

19 May 2025

New Mechanism for Selective Host-Microbe Communication in the Gut

The study reveals how APOL9 selectively binds to gut bacteria, enhancing immune responses and maintaining intestinal health through microbial communication.

15 May 2025