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Advanced Molecular Blueprints Guide Development Of Next-Generation Malaria Drugs

Researchers from the Universities of Bath and Leeds (UK) have made a significant advance in the fight against malaria by uncovering a promising new potential target for drug discovery.

7 May 2026

AI Designs New Antibiotics That Reduce MRSA Infections In Mice

SyntheMol-RL integrates reinforcement learning for antibiotic design, producing synthesizable candidates that show efficacy against MRSA in preclinical models.

5 May 2026

Discovery Shows How Plants Prevent Excess Immune Responses

Salicylic acid, the active molecule in aspirin and some acne medications, is a hormone in plants that is essential for immunity, but it's a double-edged sword: Too much can cause autoimmunity and stunt growth.

5 May 2026

New Model Explains How Genetic Information Maintains Cellular Order

A Moffitt Cancer Center researcher has introduced a new model that addresses one of biology's most fundamental questions: How does genetic information keep living systems organized and therefore alive?

5 May 2026

Accelerating Enzyme Discovery With the SMART Single-Molecule Screening System

Enzymes are proteins that catalyze chemical reactions in living organisms. They are widely applied in industries such as food production, detergents, pharmaceuticals, and chemicals.

30 Apr 2026

AI Reveals Dynamic DNA Accessibility Within Nucleosome Structures

Every cell in the human body squeezes over six feet of DNA into a miniscule speck invisible to the naked eye-like compressing a whole house into a single sugar cube.

30 Apr 2026

New Pistoia Alliance Poll Finds Regulatory Teams Benefit Most from AI, But Just 1 % See Value in the Wet Lab

The Pistoia Alliance, a global, not-for-profit that advocates for greater collaboration in life sciences R&D, has released new poll data from its annual European conference, revealing that while AI use is becoming widespread across life sciences organizations, its measurable impact on drug R&D remains limited.

From The Pistoia Alliance 29 Apr 2026

Proxygen Expands Platform Beyond Degradation to Build Next-Generation Induced Proximity Therapeutics

Proxygen, a biotechnology company pioneering the discovery of molecular glue degraders and next-generation proximity-based therapeutics, today publicly announced the expansion of its platform beyond targeted protein degradation to access a broader range of induced proximity therapeutics, while advancing two lead molecular glue degrader programs toward clinical development.

From Proxygen 29 Apr 2026

Uncovering a Second Pathway for On-Demand Glycogen Regulation

Researchers at WEHI have uncovered a never-before-seen mechanism that human bodies utilize to control sugar. These discoveries redefine basic biological principles and pave the way for new scientific discoveries.

24 Apr 2026

New Methods Increase Understanding of How Bacteria Manage DNA

New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our understanding of how bacteria manage DNA.

23 Apr 2026

Molecular Keyhole Discovery Unlocks New Target for Pain Therapies

Researchers at VIB, VUB, and KU Leuven have identified a tiny binding site, a molecular 'keyhole', in the TRPM3 ion channel, a crucial sensor in pain signaling.

22 Apr 2026

Stem Cell Model Reveals Mechanics of Early Human Embryo Development

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic manipulation.

21 Apr 2026

MIT Chemists Discover How Membrane Lipids Drive Uncontrolled Cancer Cell Growth

Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment. However, evidence has recently emerged suggesting that these membranes do more than simply provide protection - they also influence the behavior of the protein receptors embedded in them.

17 Apr 2026

Scientists Uncover How "Sorting Hubs" Clear Damaged Proteins From Cells

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled. When this system fails, damaged proteins accumulate in clumps associated with diseases such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia.

16 Apr 2026

How Single-Cell Proteomics Could Unlock the Rules That Govern Cells

This review shows how single-cell proteomics by mass spectrometry has advanced from an uncertain idea to a rapidly improving toolkit that can now quantify thousands of protein groups from individual cells. It argues that direct protein measurements, combined with better sample preparation, instrumentation, and multiplexing, could help researchers build more mechanistic models of cell biology while pushing throughput far higher.

13 Apr 2026