Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Cells Deploy Specialized Quality Control Factors When Protein Synthesis Fails

Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on Aging Research have demonstrated in a biomedical study that ribosomes, the protein factories of our cells, face an unusually tough challenge when building large, membrane‑embedded proteins.

13 Aug 2026

New Roadmap Fixes Cellular Waste Accumulation to Halt Brain Degeneration

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

13 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

New Molecular Discoveries Explain How Protein Mutations Regulate Neurological Illnesses

Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases.

3 Aug 2026

Dysfunctional Mitochondria Control Epigenetic Switches to Turn On Inflammatory Genes

Researchers have uncovered a previously unknown mechanism that helps aging cells drive the chronic inflammation linked to many age-related diseases.

31 Jul 2026

Elevated Levels of Acid Ceramidase Make Zombie Cells Susceptible to Ferroptosis

Our population is aging. The United Nations reports that by 2050, the number of people over the age of 85 on our planet is set to triple.

24 Jul 2026

Lipid Accumulation in Senescent Brain Cells Drives Aging and Alzheimer’s Disease

A new research paper was published in Volume 18 of Aging on July 1, 2026, titled "Senescent cells accumulate lipid droplets."

17 Jul 2026

Researchers Identify Crucial Cell Death in Down Syndrome

Researchers at the Alzheimer's Center at Temple have identified evidence of a new form of cell death known as necroptosis in the brains of individuals with Down Syndrome, with the corresponding biomarkers providing new clues to potential treatment also for Alzheimer's and other neurodegenerative diseases.

1 Jul 2026

Salk Institute Decodes Molecular Timeline of Age-Related Neurodegeneration

Neurodegenerative diseases affect tens of millions of people worldwide.

26 Jun 2026

New Karyoptosis Mechanism Linked to Alzheimer's and Frontotemporal Dementia

Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer's disease and frontotemporal dementia (FTD).

26 Jun 2026

Penn Study Uses AI to Discover Prion-Based Antibiotics

New antibiotic candidates for drug-resistant bacteria may reside inside prions, mis-folded protein in the brain best known for rare and fatal degenerative brain diseases.

22 Jun 2026

Scientists Identify Microglia Immune State Changes for Novel Alzheimer’s Therapies

Researchers from VIB, KU Leuven, the UK-DRI and Muna Therapeutics, funded by, among others, ERC, have uncovered a critical biological transition that may determine whether Alzheimer's disease pathology leads to dementia.

5 Jun 2026

Novel Cyclic Peptides Cross Cell Membranes to Fight Disease

Many diseases are driven by proteins interacting with each other inside cells. But blocking these interactions with drugs is difficult because our typic "small-molecule" drugs often prove to be too small to grip the broad, flat surfaces involved in protein-protein interactions.

1 Jun 2026