Neurodegenerative Disease News and Research

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Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

Blood Immune Cells Cross Protective Barriers to Transform Aging Brains

The brain's immune system has long been thought to exist independently from the rest of the body, complete with its own specialized immune cells and a blood-brain barrier that limits what can travel into the brain.

6 Aug 2026

Shuttling Gene Activating Proteins Through Packed Histones Treats Neurodegenerative Disease

Cells can switch off genes by tightly packaging DNA around proteins called histones.

6 Aug 2026

New Molecular Discoveries Explain How Protein Mutations Regulate Neurological Illnesses

Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases.

3 Aug 2026

Study Reveals How Genome Regulation Changes During Brain Aging

Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in midlife that may help explain why aging is the greatest risk factor for neurodegenerative diseases such as Alzheimer's.

24 Jul 2026

UC San Diego and Innovative Genomics Institute Partner to Develop Cutting-Edge Genomic Tools

The University of California San Diego and the Innovative Genomics Institute (IGI), founded by Nobel laureate and CRISPR gene editing co-discoverer Jennifer Doudna, announced a new partnership today to jointly develop cutting-edge genomic tools for addressing large-scale challenges in health and the environment.

21 Jul 2026

Lipid Accumulation in Senescent Brain Cells Drives Aging and Alzheimer’s Disease

A new research paper was published in Volume 18 of Aging on July 1, 2026, titled "Senescent cells accumulate lipid droplets."

17 Jul 2026

Researchers Discover Surprising Protective Microglia Roles in Dementia

Researchers at Trinity College Dublin have discovered that microglia – the main immune cells of the brain – play a critical role in maintaining the stability of neuronal networks in Alzheimer's disease.

16 Jul 2026

New Karyoptosis Mechanism Linked to Alzheimer's and Frontotemporal Dementia

Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer's disease and frontotemporal dementia (FTD).

26 Jun 2026

Penn Study Uses AI to Discover Prion-Based Antibiotics

New antibiotic candidates for drug-resistant bacteria may reside inside prions, mis-folded protein in the brain best known for rare and fatal degenerative brain diseases.

22 Jun 2026

Collaborative Research Discovers New Treatments for Alzheimer' Disease

A new multimillion-dollar project will bring together researchers from the Indiana University School of Medicine and the IU Luddy School of Informatics, Computing, and Engineering as they work to solve one of medical science's greatest needs: Identifying new treatments for Alzheimer's disease and related dementias.

16 Jun 2026

Genetically Engineered Gene Deletions Reveal Unexpected Links Between Ghrelin and Blood Glucose Stability

Hormones influence how we feel - happy, sad or hungry - and profoundly shape how our bodies function and respond to disease.

25 May 2026

A Possible Brain Fluid Recycling System In Humans

A study shows cerebrospinal fluid circulates in the brain, enhancing waste clearance and offering insights into aging and neurodegenerative disease mechanisms.

14 May 2026

Mechano-Chemo-Biological Coupling May Explain Complex Tissue Behaviors

Modern biology can now image forces, structures, and signals with remarkable precision, yet explaining how they work together remains difficult.

11 May 2026

New PanNDA Atlas Maps Protein Networks in Neurodegenerative Diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

24 Mar 2026