Neurodegenerative Diseases News and Research

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Novel Fluorescent Reporter Technology Enables Real-Time Visualization of Apoptosis Inside Cells

Cells in our body are programmed to die after a certain period of time-a natural process known as apoptosis or "cell suicide."

4 Sep 2025

Microglia Replacement Therapy Offers Hope for Genetic Disorders Affecting the Brain

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

7 Aug 2025

Case Western Researchers Use Stem Cells to “Shut Off” Nerve Cell Strain

Amyotrophic lateral sclerosis (ALS), sometimes known as Lou Gehrig’s disease, is an incurable neurological disease that affects motor neurons, which are nerve cells in the brain and spinal cord that regulate voluntary muscle movement and breathing.

6 Aug 2025

Bacterial Battle Strategies Involve Durable Amyloid Armor

Amyloids are perhaps best known as a key driver of Alzheimer's disease.

30 Jul 2025

Proteins as a Natural Weapon Against Predatory Bacteria

Amyloids are perhaps best recognized as a major cause of Alzheimer’s disease.

30 Jul 2025

Researchers Uncover Complex Substrate Profile for Enzyme Action

Research on γ-secretase reveals its unique substrate recognition mechanism, offering potential for developing precise therapeutic agents for various diseases.

14 Jul 2025

Rutgers Scientists Uncover Protein Key to Learning and Memory

Scientists have discovered how a key protein helps maintain strong connections between brain cells that are crucial for learning and memory.

14 Jul 2025

New Tool Reveals RNA Locations Inside Cells With Nanoscale Precision

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells – providing valuable clues to where different RNA species are distributed spatially in response to various cellular cues.

30 Jun 2025

Chromosome Imbalance Disrupts Mitochondria Through Protein Aggregates

It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells. Researchers at RPTU have now investigated the detailed effects of such imbalances.

30 Jun 2025

New Technique Enhances Three Dimensional Immunolabeling in Thick Tissues

Three dimensional immunohistochemistry (3D-IHC) has transformed our ability to visualize the spatial arrangement of cells and molecules in intact tissues.

20 Jun 2025

Novel Tool moPepGen Uncovers Hidden Genetic Variants at the Protein Level

Scientists at UCLA and the University of Toronto have developed an advanced computational tool, called moPepGen, that helps identify previously invisible genetic mutations in proteins, unlocking new possibilities in cancer research and beyond.

17 Jun 2025

New Platform Technology Promises to Generate Hard-to-Get Human Cells

This study presents a fast method for generating human microglia from iPSCs, paving the way for breakthroughs in neurodegenerative disease research.

11 Jun 2025

New Study Links Gut Health to Cognitive Loss in Parkinson’s

Investigating gut bacteria's impact on Parkinson's, this study highlights potential dietary and hygiene interventions to support brain health.

10 Jun 2025

UC Davis Study Links Specific microRNAs to Mental and Neurological Disorders

A study in Nature Aging from researchers at the UC Davis School of Medicine has identified specific microRNAs - non-coding RNAs that regulate gene expression within cells - that likely contribute to bipolar disorder, depression, schizophrenia, post-traumatic stress disorder (PTSD) and Parkinson's disease.

5 Jun 2025