Neurodegenerative Diseases News and Research

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Open-Chip Design Separates Fluid Resistance From Wall Confinement to Trace Cell Behavior

Most cancer studies focus on chemical signals or stiff tumor surroundings, but the stickiness of the fluid itself has received little attention. For glioblastoma, the invasion front is about eight times more viscous than the necrotic core, creating a rising resistance that migrating cells must overcome.

21 May 2026

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve responses to immunotherapy.

20 May 2026

New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

28bio today announced CNS-3D Inflammatory Organoids, designed to evaluate efficacy of anti-inflammatory drugs by quantifying their ability to reduce inflammatory injury, preserve tissue health, and restore neuronal network activity.

20 May 2026

Advanced Genomic Techniques Map Cellular Changes During Brain Aging

While much is mysterious about the aging process, change over time remains its cornerstone. The biological shifts that accompany aging seemingly occur in many cells in the body.

18 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

A Possible Brain Fluid Recycling System In Humans

A study shows cerebrospinal fluid circulates in the brain, enhancing waste clearance and offering insights into aging and neurodegenerative disease mechanisms.

14 May 2026

New CRISPR System Destroys Diseased Cells With High Precision

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched.

8 May 2026

Understanding the Origin of Early Life and Mystery of Protein Folding

How did the earliest life on Earth build complex biological machinery with so few tools? A new study explores how the simplest building blocks of proteins - once limited to just half of today's amino acids - could still form the sophisticated structures life depends on.

30 Apr 2026

Brain Immune Cells Play Key Role in Glioblastoma Tumor Infiltration

Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond the main tumor.

22 Apr 2026

Neuronal Lipid Metabolism Plays a Key Role in Preventing Metabolic Disorders

The brain is the body's command centre, and neurons are the workhorses that carry out its commands. They transmit signals that regulate many bodily functions, including key metabolic processes such as appetite, body weight and energy expenditure.

17 Apr 2026

Scientists Uncover How "Sorting Hubs" Clear Damaged Proteins From Cells

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled. When this system fails, damaged proteins accumulate in clumps associated with diseases such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia.

16 Apr 2026

Janelia Scientists Develop New Method To Study Blood-Brain Barrier Proteins

Think it was hard to get into Studio 54? Try getting through the blood-brain barrier.

10 Apr 2026

RNA Barcoding Technique Reveals Neural Connections at Synapse Level

By tagging neurons with molecular "barcodes," researchers mapped connections among thousands of neurons in the mouse brain with unprecedented speed and resolution.

8 Apr 2026

Pearling Mechanism Regulates Precise Spacing of Mitochondrial DNA

Mitochondria are often described as the cell's power plants, because they generate energy. To help them achieve this, mitochondria carry their own small genome called mitochondrial DNA (mtDNA).

3 Apr 2026

Study Reveals How STING Protein Migrates to Trigger Immune Responses

UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of interferon genes (STING) migrates from one cellular organelle to another, a necessary step in its activation.

27 Mar 2026

NAC Complex Triggers Protein Folding at Earliest Stage of Synthesis

In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps towards folding proteins into their correct three-dimensional structures.

24 Mar 2026

New PanNDA Atlas Maps Protein Networks in Neurodegenerative Diseases

Neurodegenerative diseases form a tangled biological web with overlapping molecular signatures and symptoms. To decode this complexity, a multi-institute collaboration led by St. Jude Children's Research Hospital scientists developed the pan-neurodegeneration atlas (PanNDA).

24 Mar 2026