Neurodegenerative Diseases News and Research

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Salk Institute Decodes Molecular Timeline of Age-Related Neurodegeneration

Neurodegenerative diseases affect tens of millions of people worldwide.

26 Jun 2026

New Karyoptosis Mechanism Linked to Alzheimer's and Frontotemporal Dementia

Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer's disease and frontotemporal dementia (FTD).

26 Jun 2026

Penn Study Uses AI to Discover Prion-Based Antibiotics

New antibiotic candidates for drug-resistant bacteria may reside inside prions, mis-folded protein in the brain best known for rare and fatal degenerative brain diseases.

22 Jun 2026

Migrating Neurons Break and Repair Their Own DNA During Brain Cortex Formation

Newborn nerve cells must squeeze through crowded, narrow spaces-through dense tissue, past other cells, between fibers-to reach the areas where they form neural circuits in the brain cortex.

18 Jun 2026

Study Shows Protein Fragment Reduces Neuronal Degeneration in Mice

Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have discovered a new strategy that may protect neurons and other brain cells involved in Parkinson's disease in the future.

13 Jun 2026

Scientists Discover a Metabolic Switch That Regulates Ferroptosis

The loss of an enzyme can reprogram cellular metabolism in a way that protects cells from a specific form of cell death. Paradoxically, the presumed blockade of this enzyme has the opposite effect.

1 Jun 2026

Open-Chip Design Separates Fluid Resistance From Wall Confinement to Trace Cell Behavior

Most cancer studies focus on chemical signals or stiff tumor surroundings, but the stickiness of the fluid itself has received little attention. For glioblastoma, the invasion front is about eight times more viscous than the necrotic core, creating a rising resistance that migrating cells must overcome.

21 May 2026

Sensory Nerve Signals Block the Immune System's Response to Lung Cancer

Researchers at the Francis Crick Institute have revealed that sensory nerve signals interfere with the immune system's response to lung cancer. This previously unrecognized neuroimmune connection could be targeted to improve responses to immunotherapy.

20 May 2026

New 3D Cortical Tissue Models Incorporate Microglia to Bridge Preclinical Translation Gaps

28bio today announced CNS-3D Inflammatory Organoids, designed to evaluate efficacy of anti-inflammatory drugs by quantifying their ability to reduce inflammatory injury, preserve tissue health, and restore neuronal network activity.

20 May 2026

Advanced Genomic Techniques Map Cellular Changes During Brain Aging

While much is mysterious about the aging process, change over time remains its cornerstone. The biological shifts that accompany aging seemingly occur in many cells in the body.

18 May 2026

Animals Adapt Rapidly Through Protein Networks, Not Genes

UT Southwestern Medical Center researchers have discovered a key molecular mechanism that allows animals to adapt to changing environmental conditions without altering their genes – an ability known as phenotypic plasticity.

15 May 2026

A Possible Brain Fluid Recycling System In Humans

A study shows cerebrospinal fluid circulates in the brain, enhancing waste clearance and offering insights into aging and neurodegenerative disease mechanisms.

14 May 2026

New CRISPR System Destroys Diseased Cells With High Precision

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched.

8 May 2026

Understanding the Origin of Early Life and Mystery of Protein Folding

How did the earliest life on Earth build complex biological machinery with so few tools? A new study explores how the simplest building blocks of proteins - once limited to just half of today's amino acids - could still form the sophisticated structures life depends on.

30 Apr 2026

Brain Immune Cells Play Key Role in Glioblastoma Tumor Infiltration

Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it can infiltrate surrounding brain tissue and spread far beyond the main tumor.

22 Apr 2026

Neuronal Lipid Metabolism Plays a Key Role in Preventing Metabolic Disorders

The brain is the body's command centre, and neurons are the workhorses that carry out its commands. They transmit signals that regulate many bodily functions, including key metabolic processes such as appetite, body weight and energy expenditure.

17 Apr 2026

Scientists Uncover How "Sorting Hubs" Clear Damaged Proteins From Cells

Inside every cell, a cleanup operation runs around the clock. Proteins are constantly damaged by wear and tear. Some can be repaired, while others must be dismantled and recycled. When this system fails, damaged proteins accumulate in clumps associated with diseases such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia.

16 Apr 2026