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Innovative OpenFISH Technique Enables Integrated Spatial Molecular Imaging in Tissues

Spatial transcriptomics (ST) shows which genes are being expressed and where within a tissue. Spatial metabolomics (SM), on the other hand, maps the location of metabolites—small molecules produced or used by cells—within tissue.

30 Sep 2026

Study Establishes Immune Cell Trafficking as Viable Alzheimer's Target

There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.

29 Sep 2026

Scientists Pinpoint the Brain Circuit That Regulates Metabolism

As the body’s temperature decreases, it compensates by utilizing additional energy to produce heat and stimulating the desire to eat to replenish the energy expended for warmth.

28 Sep 2026

Individual Neurons Display Trial-to-Trial Firing Rate Variability Under Identical Visual Stimulation

Our brains internally represent the outside world through the coordinated activity of billions of neurons.

25 Sep 2026

How Feedback Mechanisms Control Neural Chaos for Stable Visual Processing

What we see appears stable, even though neuronal activity is full of irregular fluctuations. A team led by Dr Mehdi Borjkhani from ICTER has shown, using a minimal model of the primary visual cortex, that two natural feedback mechanisms can constrain chaos and reduce variability in neural activity by up to 93 percent.

23 Sep 2026

KAIST Researchers Develop NUDGE to Steer Cell States Without Permanent Alteration

Which genes need to be controlled to guide a stem cell toward a desired cell type, or to modulate an immune cell's inflammatory response? A Korean research team has developed a general-purpose computational framework that identifies the key targets needed to steer a cell toward a desired state with a single temporary intervention, without permanently altering its genes.

23 Sep 2026

What Drives Pregnancy Cravings? Researchers Find a Clue in the Brain

What causes intense food cravings during pregnancy? Scientists at LSU’s Pennington Biomedical Research Center, working alongside collaborators, have pinpointed a neural mechanism that may explain how pregnancy influences the desire to pursue certain highly appealing foods.

22 Sep 2026

Breakthrough Study Explains Developmental Origins of the Human Brain

For centuries, scientists have thought of the brain as a single, unified organ. But new research led by Stanford Medicine reveals that what we call the brain is two distinct organs that evolved independently over hundreds of millions of years.

21 Sep 2026

Novel Base-Editing Approach Shows Promise for Inherited Motor Neuron Disorders

A team of researchers led by Professor Haruhisa Inoue (Center for iPS Cell Research and Application, Kyoto University) and Professor Yuishin Izumi (Tokushima University) demonstrated that adenine base editing can correct a disease-causing genetic mutation and alleviate neurodegeneration in hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P), providing proof of concept for a precision gene therapy for inherited motor neuron diseases.

21 Sep 2026

Study Maps Precise Anatomical Circuits Within the Brainstem Locus Coeruleus

Deep in the brainstem sits a small but important cluster of neurons known as the locus coeruleus (LC), Latin for "blue place."

21 Sep 2026

Scientists Grow Human Brain Organoids in Cortex-Depleted Mice

Stanford Medicine scientists have chalked up a major advance in growing human brain cells outside of the human brain - and outside of laboratory glassware.

17 Sep 2026

Researchers Propose Roadmap for Brain-Wide Lifetime Electrophysiology in Mammalian Models

Understanding the brain requires tools that can follow neural activity across many scales: from millisecond electrical spikes in individual neurons to brain-wide circuit dynamics that change over months, years, and even a lifetime.

10 Sep 2026

Genetic Toolkit Helps Researchers Map Single Neurons in Fruit Flies

Our brains constantly integrate information about both our internal state and our surroundings to determine how we behave.

28 Aug 2026

Colorectal Cancer and Nerve Damage: A Hidden Link Uncovered in Mice and Primates

Colorectal tumors trigger inflammatory nerve damage, suggesting cancer itself may be a risk factor for neuropathy in survivors, independent of treatments.

27 Aug 2026

Reengineering Glial Cell Signaling Pathways to Slow Down ALS Symptoms

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that, according to the CDC, currently impacts around 35,000 Americans-with 5,000 more diagnosed each year.

21 Aug 2026

High-Speed Microscope Captures Millisecond-Scale Brain Signaling Activity

Within the brain, neurons compute by generating electrical impulses. These signals travel throughout neurons, which are in turn connected in vast networks that control brain functions such as sensory perception, memory formation, and control of movement.

17 Aug 2026

Researchers Map Immune Molecule Behavior in Affected Motor Neurons

Immune-related molecules change in motor neurons affected by amyotrophic lateral sclerosis (ALS), but they do not appear to be major drivers of disease progression.

17 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Researchers Identify Neurons Responsible for Regulating Motivated Behavior

What enables us to sustain effort toward goals, even when the task becomes increasingly difficult? A recent study by researchers at Nagoya University in Japan revealed the underlying brain mechanism, showing that orexin neurons play a crucial role in driving and regulating motivated behavior.

3 Aug 2026

FlatMux Imaging Platform Captures Live Brain Circuit Activity

The brain is a vast, densely interconnected network of neurons computing in parallel. Watching these computations unfold in real time could reveal how the brain processes sensation and guides behavior.

24 Jul 2026