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Hidden Neuronal Lattice May Shield the Brain From Alzheimer’s

Brain cells are constantly swallowing material from the fluid that surrounds them - signaling molecules, nutrients, even pieces of their own surfaces - in a process known as endocytosis that is essential for learning, memory and basic neural upkeep.

12 Feb 2026

Bone-building hormone eases chronic low back pain by restoring vertebral microarchitecture

Parathyroid hormone shows promise in treating low back pain by remodeling degenerating vertebral endplates and limiting pathological sensory innervation.

12 Feb 2026

Reprogrammed Engrams Reverse Cognitive Decline in Mice

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible.

11 Feb 2026

Brain's Aging Waste System Linked to Synapse Loss and Cognitive Decline

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why.

3 Feb 2026

Using a Powerful Technology to Track Body's Most Elusive Proteins

What can a single molecule in just one of the body's cells reveal about a person's health? Quite a lot if you can find it. Cedars-Sinai investigators are doing just that.

28 Jan 2026

Neuronal Activity Maps Challenge Traditional Anatomical Divisions of Prefrontal Cortex

For more than a century, maps of the brain have been based on how brain tissue looks under the microscope.

21 Jan 2026

Computational Brain Model Predicts Errors, Uncovers Previously Unseen Neurons

A new computational model of the brain based closely on its biology and physiology not only learned a simple visual category learning task exactly as well as lab animals, but even enabled the discovery of counterintuitive activity by a group of neurons that researchers working with animals to perform the same task had not noticed in their data before, said a team of scientists at Dartmouth College, MIT, and the State University of New York at Stony Brook.

30 Dec 2025

Study Reveals Glucose-Driven Mitochondrial Migration in Beta Cells

Unlike our organs, cell organelles such as mitochondria are not fixed in place, but when, where, how, and why organelles move remain unclear.

19 Dec 2025

Neuron Anatomy Shapes How the Brain Processes Odor Information

Closely related subtypes of dopamine-releasing neurons may play entirely separate roles in processing sensory information, depending on their physical structure.

17 Dec 2025

Changes in the Activity of KCC2 Protein Influence Reward Learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

11 Dec 2025

MiniVolt Microscope Captures Neuron Voltage Signals in Freely Moving Animals

Researchers have built a tiny, lightweight microscope that captures neuron activity with unprecedented speed that can be used in freely moving animals.

8 Dec 2025

Single-Cell RNA Imaging Uncovers Four Distinct Neuron Bands in the Hippocampus

Researchers at the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have identified a previously unknown pattern of organization in one of the brain's most important areas for learning and memory.

4 Dec 2025

Scientists Uncover Inner Workings of Biomolecular Condensates Linked to ALS

Inside the cell reside many tiny assembly factories and warehouses that gather together all of the proteins and RNAs-which carry out instructions from our DNA-that a living being needs.

27 Nov 2025

New Technique Reveals Synaptic Vesicle Dynamics in Living Brain Tissue

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Researchers Reveal How the Brain Forms Hidden-State Inferences

Animals survive in changing and unpredictable environments by not merely responding to new circumstances, but also, like humans, by forming inferences about their surroundings-for instance, squirrels understand that certain bird noises don't signal the presence of a predator, so won't seek shelter when they later hear these same sounds.

18 Nov 2025

Rare Stress-Sensitive Neurons Hold the Key to Healthy Brain Blood Flow

While the exact causes of neurodegenerative brain diseases like Alzheimer's and dementia are still largely unknown, researchers have been able to identify a key characteristic in affected brains: reduced blood flow.

12 Nov 2025

Scientists Uncover How "P Bodies" Guide Stem Cells to Their Destinies

How do stem cells know what to become? Nearly three decades after scientists isolated the first human embryonic stem cells, researchers are still working hard to understand precisely how a single, undifferentiated cell can become any one of the roughly 200 cell types that make up the human body.

4 Nov 2025

Study Reveals Shared Genetic Roots Between ALS and Hereditary Spastic Paraplegia

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct.

3 Nov 2025

Frazzled Protein Found to Shape Fast Neural Connections in Fruit Flies

Florida Atlantic University neuroscientists have uncovered a surprising role for a protein named "Frazzled" (known as DCC in mammals) in the nervous system of fruit flies, showing how it helps neurons connect and communicate with lightning speed.

3 Nov 2025

Research Sheds New Light On How Neurons Transmit Strains and Stresses

How do embryos develop? Why does the cortex of the mammalian brain fold? How do we feel touch at our fingertips? These and other fundamental biological questions remain unsolved. Yet, scientists know they all rely on a common principle: the conversion of a physical stimulus into a biochemical signal.

30 Oct 2025