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Reengineering Glial Cell Signaling Pathways to Slow Down ALS Symptoms

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that, according to the CDC, currently impacts around 35,000 Americans-with 5,000 more diagnosed each year.

21 Aug 2026

Study Uncovers Cellular Accumulators Tracking Brain Electronic Sleep Pressure

Why does staying awake inevitably make us sleepy? Researchers at the University of Basel, Switzerland, have identified neuronal populations in the brain of mice that become activated during prolonged wakefulness and are crucial for sleep drive.

20 Aug 2026

Innovative LATeNT Platform Controls Neural Paths to Treat Brain Disorders

DGIST (President Kunwoo Lee) announced that a research team led by Professor Ji Won Um of the Center for Synapse Diversity and Specificity, Department of Brain Sciences, in collaboration with a research team led by Professor Alice Ting at Stanford University, has developed LATeNT, a novel optical control platform that uses light to block signal transmission between neurons and subsequently restore normal signaling.

19 Aug 2026

New Potential Target for Triple-Negative Breast Cancer

The study uncovers how macrophages recruit nerves in triple-negative breast cancer, suggesting BDNF signaling as a critical factor in tumor progression.

18 Aug 2026

Modular Brain Structures Reuse Neural Networks to Simplify Complex Actions

As we move through everyday life, our brains engage in a huge variety of cognitive tasks. For example, during a grocery run, we might have to recall the items for a recipe, remember where the clerk said the flour was located, and count out money to pay.

18 Aug 2026

Breakthrough Discovery Pinpoints How Brain Immune Cells Respond to Toxic Cellular Waste

Researchers at the University of California, San Diego, and their colleagues have discovered a critical cellular mechanism that causes brain degeneration in both a rare childhood condition and the far more prevalent Alzheimer’s disease.

17 Aug 2026

High-Speed Microscope Captures Millisecond-Scale Brain Signaling Activity

Within the brain, neurons compute by generating electrical impulses. These signals travel throughout neurons, which are in turn connected in vast networks that control brain functions such as sensory perception, memory formation, and control of movement.

17 Aug 2026

Researchers Map Immune Molecule Behavior in Affected Motor Neurons

Immune-related molecules change in motor neurons affected by amyotrophic lateral sclerosis (ALS), but they do not appear to be major drivers of disease progression.

17 Aug 2026

New Study Links TIMP2 Loss to Microglial Immune Dysfunction

Researchers at The Icahn School of Medicine at Mount Sinai have identified a role for the youth-associated protein TIMP2 in supporting the healthy function of microglia, the brain's resident immune cells.

17 Aug 2026

New Mouse Study Challenges Traditional Theories of Long-Term Memory Storage

Memories can survive even after the brain temporarily loses more than half of its synaptic connections, according to a new mouse study, which challenges the long-held view that long-term memories depend on stable individual synapses.

14 Aug 2026

New Roadmap Fixes Cellular Waste Accumulation to Halt Brain Degeneration

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

13 Aug 2026

New Single-Cell Database Reveals Hidden Inner Workings of Spinal Cord Circuits

Scientists at St. Jude Children's Research Hospital created a single-cell atlas of a key class of spinal neurons involved in motor coordination. From that resource, they identified a small subgroup of interneurons associated with the speed of rhythmic movements such as walking. The findings, which have implications for understanding spinal cord function and recovery from injury, were published today in Nature Communications.

11 Aug 2026

Brain Executive Control Centers Block Creative Problem Solving in Mice

The prefrontal cortex, a brain region long associated with learning more flexible behaviors, can sometimes block the ability to think outside the box, a new study in mice shows. Science Advances published the finding by biologists at Emory University.

8 Aug 2026

Research Reevaluates Crucial Microtubule Stabilizing Protein in Dementia Progression

A protein named tau, which has been highly implicated in the world's No. 1 cause of dementia - Alzheimer's disease - and several other neurodegenerative disorders, may spur these diseases in a way that differs greatly from the pathological pathway usually ascribed to it.

7 Aug 2026

Emerging m6A RNA Biology Explains Brain Vulnerability to Environmental Hazards

A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease.

7 Aug 2026

Researchers Identify Neurons Responsible for Regulating Motivated Behavior

What enables us to sustain effort toward goals, even when the task becomes increasingly difficult? A recent study by researchers at Nagoya University in Japan revealed the underlying brain mechanism, showing that orexin neurons play a crucial role in driving and regulating motivated behavior.

3 Aug 2026