Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Long-Read Nanopore Sequencing Resolves Unexplained Tumor Mutations

Michigan's Oncology Sequencing Program, or MiOncoSeq, was the first of its kind in the nation to sequence patient tumors.

24 Oct 2026

Evaxion Announces 89% Vaccine Target Precision and Sustained T-Cell and Clinical Responses at Three-Year Follow-Up in Phase 2 Trial with Personalized Cancer Vaccine EVX-01

Evaxion A/S, a clinical-stage TechBio company developing novel immunotherapies with its pioneering AI-Immunology™ platform, announces new three-year immune and clinical outcome data for personalized cancer vaccine EVX-01 in patients with advanced melanoma.

From Evaxion A/S 24 Oct 2026

Carrier-Free Jet Vaccine Method Protects Against COVID-19 and Flu in Animal Studies

A needle-free vaccination method protected mice against the viruses that cause COVID-19 and flu, offering a possible new way to deliver mRNA vaccines while limiting unwanted inflammation.

24 Oct 2026

BioUK Awards 2026 Celebrate Outstanding Achievement and Breakthrough Innovations from Across the Life Sciences

BioUK, the not-for-profit membership organization focused on catalyzing success in UK life sciences, today announced the winners of the 18th annual BioUK Awards following a ceremony hosted at the Royal Lancaster Hotel, London.

From BioUK 23 Oct 2026

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Immune checkpoint inhibitors (ICIs) have transformed cancer care, yet only a subset of patients benefit. A major barrier is tumor microenvironment (TME) heterogeneity: "hot" tumors are enriched with cytotoxic T lymphocytes (CTLs) and respond better, while "cold" tumors lack T-cell infiltration or are shielded by immunosuppressive barriers.

20 Oct 2026

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Mitochondrial serine catabolic pathway (MSCP), also called serine, glycine, and one-carbon metabolism, is essential for cancer cells to produce amino acids, one-carbon units, and reducing equivalents.

20 Oct 2026

Comprehensive Analysis of Emerging Strategies for Targeting Cyclin-Dependent Kinases in Cancer

More than 30 years after the direct connection was established between the molecular machinery controlling cell division and cancer, a new paper traces the evolution of cyclin-dependent kinase research and outlines the next generation of CDK-targeted therapies.

15 Oct 2026

New AI Model Decodes the Language of Immune Cell Movement

Researchers at The University of Texas MD Anderson Cancer Center and collaborating institutions in Texas developed an artificial intelligence (AI) model that helps explain how immune cells find their way to specific locations in the body and why they avoid others.

14 Oct 2026

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood. St. Jude Children's Research Hospital scientists and their collaborators built one of the most comprehensive datasets of neuroblastoma cells to date, using it to define the tumor's cell types and identify a gene signature marking a malignant cell population tied to poor prognosis.

10 Oct 2026

Single-Cell RNA Sequencing Reveals Cellular Heterogeneity Across Distinct Anatomical Prostate Zones

Researchers at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center have identified a distinct type of prostate cell that may help solve the long-standing mystery of why benign prostatic hyperplasia (BPH) - a noncancerous enlargement of the prostate that commonly affects men as they age - develops almost exclusively in one region of the prostate.

7 Oct 2026

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of the Division of Medical Oncology/Hematology at Kobe University Hospital, together with Associate Professor Goh Ohji of the Division of Infectious Disease Therapeutics and Takaji Matsutani of Anymics Inc., has developed the pGen-SHM plot.

5 Oct 2026

Dr. GPCR and Eurofins Discovery Join Forces to Advance GPCR Drug Discovery

Dr. GPCR, the global knowledge hub for G protein-coupled receptor (GPCR) research and education, today announced a strategic partnership with Eurofins Discovery, the drug discovery services side of the same group behind the Eurofins DiscoverX products many in the community already know.

From Dr. GPCR 5 Oct 2026

USP15 Protein May Help Ovarian Cancer Resist Chemotherapy

Blocking USP15 in ovarian cancer cells disrupts growth and enhances chemotherapy sensitivity, revealing a potential target for overcoming treatment resistance.

1 Oct 2026

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Immune cells can reach head and neck tumors, but once there, many stop functioning. This helps explain why immunotherapy with immune checkpoint inhibitors - which have transformed treatment for some cancers - benefit only 17%–23% of patients with head and neck squamous cell carcinoma. These are cancers that arise from cells lining the mouth, throat and voicebox.

1 Oct 2026

Personalized Support Boosts Genetic Testing Uptake Among At-Risk Family Members

Among cancer patients who received personalized support and navigation services from experts throughout the genetic testing process, their first-degree relatives – parents, siblings and children – were significantly more likely to receive genetic testing, as well. Nearly half of those relatives carried a BRCA1 or BRCA2 mutation, which are associated with a higher risk of cancer, according to a new study by researchers at The University of Texas MD Anderson Cancer Center.

30 Sep 2026

Cancer-Associated Fibroblasts Construct Physical Barriers Limiting Antitumor T Cell Infiltration

Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown pathway that prostate tumors leverage to suppress the immune system by reshaping the tumor microenvironment to resist treatment.

25 Sep 2026

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers at Memorial Sloan Kettering Cancer Center (MSK) and their colleagues have discovered that a type of rogue DNA found in aggressive cancers has a hidden structural weakness - and that blocking a single repair protein can cause it to fall apart, suggesting a new therapeutic opportunity.

24 Sep 2026

Oncology News and Research

Long-Read Nanopore Sequencing Resolves Unexplained Tumor Mutations

Evaxion Announces 89% Vaccine Target Precision and Sustained T-Cell and Clinical Responses at Three-Year Follow-Up in Phase 2 Trial with Personalized Cancer Vaccine EVX-01

Carrier-Free Jet Vaccine Method Protects Against COVID-19 and Flu in Animal Studies

BioUK Awards 2026 Celebrate Outstanding Achievement and Breakthrough Innovations from Across the Life Sciences

Dendritic Cell STING Activation Licenses Cytotoxic T Lymphocyte Priming

Stable Isotope Carbon Tracing Proves Uncoupling Inhibits De Novo Purine Synthesis

Comprehensive Analysis of Emerging Strategies for Targeting Cyclin-Dependent Kinases in Cancer

New AI Model Decodes the Language of Immune Cell Movement

Single-Cell RNA Sequencing Maps Neuroblastoma Intratumoral Heterogeneity

Single-Cell RNA Sequencing Reveals Cellular Heterogeneity Across Distinct Anatomical Prostate Zones

Novel Two-Dimensional Mapping Combines Generation Probability with Somatic Hypermutation

Dr. GPCR and Eurofins Discovery Join Forces to Advance GPCR Drug Discovery

USP15 Protein May Help Ovarian Cancer Resist Chemotherapy

Single-Cell Metabolic Profiling Identifies Key Bioenergetic Targets in Human Tumor Tissue

Personalized Support Boosts Genetic Testing Uptake Among At-Risk Family Members

Cancer-Associated Fibroblasts Construct Physical Barriers Limiting Antitumor T Cell Infiltration

Study Uncovers Two-Protein Repair Mechanism Preserving Circular ecDNA Stability

Researchers Reveal How p53 Tumor-Suppressor Protein Hide From T Cells

Researchers Analyze Somatic DNA Integrity across Complex Longevity Pathways

Activating TRPC1 Protein Channels With Magnetic Fields Triggers Cancer Phagocytosis

The Future of Vision Restoration With ReVision Implant

How a Single List Is Changing Visibility for Women in Science

How Avatar Medical's 3D Technology Is Transforming How We Visualize the Human Body

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